microglia Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description The small, non-neural, interstitial cells of mesodermal origin that form part of the supporting structure of the central nervous system. They are of various forms and may have slender branched processes. They are migratory and act as phagocytes to waste products of nerve tissue. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000078)
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Genes

119 genes co-occuring with the biological term microglia in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADGRE5 adhesion G protein-coupled receptor E5
ADORA2A adenosine A2a receptor
AGER advanced glycosylation end product-specific receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
APCS amyloid P component, serum
APP amyloid beta (A4) precursor protein
BECN1 beclin 1, autophagy related
BIRC3 baculoviral IAP repeat containing 3
C1QA complement component 1, q subcomponent, A chain
C3 complement component 3
CCL2 chemokine (C-C motif) ligand 2
CCL21 chemokine (C-C motif) ligand 21
CCL8 chemokine (C-C motif) ligand 8
CCNT1 cyclin T1
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD163 CD163 molecule
CD200 CD200 molecule
CD200R1 CD200 receptor 1
CD4 CD4 molecule
CD68 CD68 molecule
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CLIC1 chloride intracellular channel 1
CNR2 cannabinoid receptor 2 (macrophage)
CRYAB crystallin, alpha B
CX3CL1 chemokine (C-X3-C motif) ligand 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CYBB cytochrome b-245, beta polypeptide
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DISC1 disrupted in schizophrenia 1
DOCK2 dedicator of cytokinesis 2
EBAG9 estrogen receptor binding site associated, antigen, 9
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPO erythropoietin
ESR2 estrogen receptor 2 (ER beta)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAAH fatty acid amide hydrolase
FAS Fas cell surface death receptor
GPX1 glutathione peroxidase 1
GRB2 growth factor receptor-bound protein 2
GRN granulin
HMGB1 high mobility group box 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HTT huntingtin
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IL10 interleukin 10
IL16 interleukin 16
IL1B interleukin 1, beta
IL23A interleukin 23, alpha subunit p19
IL34 interleukin 34
IL4 interleukin 4
IL7 interleukin 7
IRF3 interferon regulatory factor 3
KCNK9 potassium channel, two pore domain subfamily K, member 9
KDM6B lysine (K)-specific demethylase 6B
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LCN2 lipocalin 2
LPAR1 lysophosphatidic acid receptor 1
LPAR2 lysophosphatidic acid receptor 2
LPAR3 lysophosphatidic acid receptor 3
MAPK14 mitogen-activated protein kinase 14
MARVELD2 MARVEL domain containing 2
MIR146A microRNA 146a
MMP12 matrix metallopeptidase 12
MOK MOK protein kinase
MPO myeloperoxidase
MST1 macrophage stimulating 1
NCOA3 nuclear receptor coactivator 3
NCR1 natural cytotoxicity triggering receptor 1
NF1 neurofibromin 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOS2 nitric oxide synthase 2, inducible
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLG plasminogen
PRNP prion protein
PSEN1 presenilin 1
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PTGES prostaglandin E synthase
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SIGLEC11 sialic acid binding Ig-like lectin 11
SIRT5 sirtuin 5
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TACR1 tachykinin receptor 1
TBCB tubulin folding cofactor B
TDO2 tryptophan 2,3-dioxygenase
TFAM transcription factor A, mitochondrial
TGFB1 transforming growth factor, beta 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TP53 tumor protein p53
TPSAB1 tryptase alpha/beta 1
TREM2 triggering receptor expressed on myeloid cells 2
TSPO translocator protein (18kDa)
WISP1 WNT1 inducible signaling pathway protein 1
WNT1 wingless-type MMTV integration site family, member 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YY1 YY1 transcription factor