microtubule organizing center Gene Set

Dataset COMPARTMENTS Experimental Protein Localization Evidence Scores
Category proteomics
Type cellular component
Description An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides. (Gene Ontology, GO_0005815)
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Genes

290 proteins localized to the microtubule organizing center cellular component in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
PCNT pericentrin 1.9544
CDK5RAP2 CDK5 regulatory subunit associated protein 2 1.9544
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 1.02676
PCM1 pericentriolar material 1 1.02676
WDR37 WD repeat domain 37 1.02676
TACC3 transforming, acidic coiled-coil containing protein 3 1.02676
C11ORF80 chromosome 11 open reading frame 80 1.02676
C15ORF43 chromosome 15 open reading frame 43 1.02676
MKKS McKusick-Kaufman syndrome 1.02676
CEP170 centrosomal protein 170kDa 1.02676
PVRL3 poliovirus receptor-related 3 1.02676
TTI2 TELO2 interacting protein 2 1.02676
PCYT2 phosphate cytidylyltransferase 2, ethanolamine 1.02676
ZNF766 zinc finger protein 766 1.02676
AACS acetoacetyl-CoA synthetase 0.233497
NFE2L2 nuclear factor, erythroid 2-like 2 0.233497
MDH1 malate dehydrogenase 1, NAD (soluble) 0.233497
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.233497
MAP7D3 MAP7 domain containing 3 0.233497
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.233497
MYCBP MYC binding protein 0.233497
NDRG2 NDRG family member 2 0.233497
PEAR1 platelet endothelial aggregation receptor 1 0.233497
CROCC ciliary rootlet coiled-coil, rootletin 0.233497
AVEN apoptosis, caspase activation inhibitor 0.233497
APOA4 apolipoprotein A-IV 0.233497
CDC45 cell division cycle 45 0.233497
TTC39A tetratricopeptide repeat domain 39A 0.233497
WDR60 WD repeat domain 60 0.233497
MED20 mediator complex subunit 20 0.233497
MAPRE1 microtubule-associated protein, RP/EB family, member 1 0.233497
KEAP1 kelch-like ECH-associated protein 1 0.233497
WDR83 WD repeat domain 83 0.233497
ADCK2 aarF domain containing kinase 2 0.233497
COBL cordon-bleu WH2 repeat protein 0.233497
N4BP2 NEDD4 binding protein 2 0.233497
PRICKLE3 prickle homolog 3 (Drosophila) 0.233497
RENBP renin binding protein 0.233497
THAP6 THAP domain containing 6 0.233497
BCAR3 breast cancer anti-estrogen resistance 3 0.233497
RPAP3 RNA polymerase II associated protein 3 0.233497
ATP11B ATPase, class VI, type 11B 0.233497
MICALL1 MICAL-like 1 0.233497
FOPNL FGFR1OP N-terminal like 0.233497
RAB23 RAB23, member RAS oncogene family 0.233497
PKN2 protein kinase N2 0.233497
WDR90 WD repeat domain 90 0.233497
MDM1 Mdm1 nuclear protein homolog (mouse) 0.233497
PLK4 polo-like kinase 4 0.233497
LGI2 leucine-rich repeat LGI family, member 2 0.233497
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 0.233497
LONRF1 LON peptidase N-terminal domain and ring finger 1 0.233497
HIPK1 homeodomain interacting protein kinase 1 0.233497
ENGASE endo-beta-N-acetylglucosaminidase 0.233497
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) 0.233497
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 0.233497
SMAD4 SMAD family member 4 0.233497
ZFAND1 zinc finger, AN1-type domain 1 0.233497
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 0.233497
UXT ubiquitously-expressed, prefoldin-like chaperone 0.233497
CEP97 centrosomal protein 97kDa 0.233497
C12ORF73 chromosome 12 open reading frame 73 0.233497
CEP152 centrosomal protein 152kDa 0.233497
CLEC11A C-type lectin domain family 11, member A 0.233497
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.233497
MED12 mediator complex subunit 12 0.233497
SNAP29 synaptosomal-associated protein, 29kDa 0.233497
FLII flightless I homolog (Drosophila) 0.233497
FAM184A family with sequence similarity 184, member A 0.233497
CYLD cylindromatosis (turban tumor syndrome) 0.233497
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.233497
HAUS2 HAUS augmin-like complex, subunit 2 0.233497
HAUS7 HAUS augmin-like complex, subunit 7 0.233497
LIPT2 lipoyl(octanoyl) transferase 2 (putative) 0.233497
KATNA1 katanin p60 (ATPase containing) subunit A 1 0.233497
ATF4 activating transcription factor 4 0.233497
TDRKH tudor and KH domain containing 0.233497
TUB tubby bipartite transcription factor 0.233497
TMC3 transmembrane channel-like 3 0.233497
ZNF76 zinc finger protein 76 0.233497
AATF apoptosis antagonizing transcription factor 0.233497
CYB5D2 cytochrome b5 domain containing 2 0.233497
CSK c-src tyrosine kinase 0.233497
FRMD4B FERM domain containing 4B 0.233497
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.233497
CCDC66 coiled-coil domain containing 66 0.233497
KIFAP3 kinesin-associated protein 3 0.233497
MCM3 minichromosome maintenance complex component 3 0.233497
FAM63A family with sequence similarity 63, member A 0.233497
SLC35A5 solute carrier family 35, member A5 0.233497
BRMS1 breast cancer metastasis suppressor 1 0.233497
PNPLA7 patatin-like phospholipase domain containing 7 0.233497
GPR132 G protein-coupled receptor 132 0.233497
DNAL1 dynein, axonemal, light chain 1 0.233497
DNAL4 dynein, axonemal, light chain 4 0.233497
BUD31 BUD31 homolog (S. cerevisiae) 0.233497
KIF5B kinesin family member 5B 0.233497
ATG5 autophagy related 5 0.233497
MYO5A myosin VA (heavy chain 12, myoxin) 0.233497
NIN ninein (GSK3B interacting protein) 0.233497
HPS4 Hermansky-Pudlak syndrome 4 0.233497
TUBGCP5 tubulin, gamma complex associated protein 5 0.233497
TUBGCP4 tubulin, gamma complex associated protein 4 0.233497
AK5 adenylate kinase 5 0.233497
UNC5CL unc-5 homolog C (C. elegans)-like 0.233497
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.233497
CEP164 centrosomal protein 164kDa 0.233497
PAN3 PAN3 poly(A) specific ribonuclease subunit 0.233497
TSEN2 TSEN2 tRNA splicing endonuclease subunit 0.233497
C9ORF40 chromosome 9 open reading frame 40 0.233497
EDRF1 erythroid differentiation regulatory factor 1 0.233497
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 0.233497
TRIM38 tripartite motif containing 38 0.233497
SOCS6 suppressor of cytokine signaling 6 0.233497
GINS4 GINS complex subunit 4 (Sld5 homolog) 0.233497
WDR34 WD repeat domain 34 0.233497
TSSC1 tumor suppressing subtransferable candidate 1 0.233497
SYNJ1 synaptojanin 1 0.233497
TXLNA taxilin alpha 0.233497
SNORA25 small nucleolar RNA, H/ACA box 25 0.233497
NCAN neurocan 0.233497
ZRANB3 zinc finger, RAN-binding domain containing 3 0.233497
DPF2 D4, zinc and double PHD fingers family 2 0.233497
FRMD5 FERM domain containing 5 0.233497
SOGA3 SOGA family member 3 0.233497
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.233497
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 0.233497
AKAP9 A kinase (PRKA) anchor protein 9 0.233497
AKAP7 A kinase (PRKA) anchor protein 7 0.233497
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.233497
AUNIP aurora kinase A and ninein interacting protein 0.233497
CCDC15 coiled-coil domain containing 15 0.233497
ZNF280D zinc finger protein 280D 0.233497
MTMR11 myotubularin related protein 11 0.233497
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 0.233497
OSGEP O-sialoglycoprotein endopeptidase 0.233497
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.233497
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase 0.233497
CAPRIN2 caprin family member 2 0.233497
PODXL podocalyxin-like 0.233497
JAZF1 JAZF zinc finger 1 0.233497
KIAA1109 KIAA1109 0.233497
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 0.233497
STXBP1 syntaxin binding protein 1 0.233497
GAS6 growth arrest-specific 6 0.233497
RAB11FIP5 RAB11 family interacting protein 5 (class I) 0.233497
RAB11FIP3 RAB11 family interacting protein 3 (class II) 0.233497
RAB15 RAB15, member RAS oncogene family 0.233497
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.233497
ATG4A autophagy related 4A, cysteine peptidase 0.233497
DAPK1 death-associated protein kinase 1 0.233497
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.233497
DDHD2 DDHD domain containing 2 0.233497
SFR1 SWI5-dependent recombination repair 1 0.233497
P2RY11 purinergic receptor P2Y, G-protein coupled, 11 0.233497
HSCB HscB mitochondrial iron-sulfur cluster co-chaperone 0.233497
TYSND1 trypsin domain containing 1 0.233497
NIT2 nitrilase family, member 2 0.233497
KIAA0753 KIAA0753 0.233497
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 0.233497
TWSG1 twisted gastrulation BMP signaling modulator 1 0.233497
CEMIP cell migration inducing protein, hyaluronan binding 0.233497
OBSL1 obscurin-like 1 0.233497
ZFP90 ZFP90 zinc finger protein 0.233497
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.233497
ZNF274 zinc finger protein 274 0.233497
CLDND1 claudin domain containing 1 0.233497
RIC8B RIC8 guanine nucleotide exchange factor B 0.233497
CHMP1A charged multivesicular body protein 1A 0.233497
UBQLN4 ubiquilin 4 0.233497
COL21A1 collagen, type XXI, alpha 1 0.233497
PRSS8 protease, serine, 8 0.233497
HOOK3 hook microtubule-tethering protein 3 0.233497
OAZ1 ornithine decarboxylase antizyme 1 0.233497
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) 0.233497
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) 0.233497
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa 0.233497
KXD1 KxDL motif containing 1 0.233497
C16ORF74 chromosome 16 open reading frame 74 0.233497
CPA4 carboxypeptidase A4 0.233497
SLAIN2 SLAIN motif family, member 2 0.233497
MBP myelin basic protein 0.233497
CEP192 centrosomal protein 192kDa 0.233497
KIAA2018 KIAA2018 0.233497
DCTN2 dynactin 2 (p50) 0.233497
AAAS achalasia, adrenocortical insufficiency, alacrimia 0.233497
NUP107 nucleoporin 107kDa 0.233497
ARHGAP40 Rho GTPase activating protein 40 0.233497
RSRC2 arginine/serine-rich coiled-coil 2 0.233497
MPHOSPH9 M-phase phosphoprotein 9 0.233497
PGLS 6-phosphogluconolactonase 0.233497
NGLY1 N-glycanase 1 0.233497
CCP110 centriolar coiled coil protein 110kDa 0.233497
FKBP11 FK506 binding protein 11, 19 kDa 0.233497
SORBS1 sorbin and SH3 domain containing 1 0.233497
SNAP91 synaptosomal-associated protein, 91kDa 0.233497
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 0.233497
CCDC176 coiled-coil domain containing 176 0.233497
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.233497
GSDMC gasdermin C 0.233497
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.233497
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 0.233497
GPR142 G protein-coupled receptor 142 0.233497
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative) 0.233497
LRRC7 leucine rich repeat containing 7 0.233497
KIFC1 kinesin family member C1 0.233497
TSPYL2 TSPY-like 2 0.233497
ZNF519 zinc finger protein 519 0.233497
INPP1 inositol polyphosphate-1-phosphatase 0.233497
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 0.233497
CEP128 centrosomal protein 128kDa 0.233497
TRIM2 tripartite motif containing 2 0.233497
FAM45A family with sequence similarity 45, member A 0.233497
CHPF chondroitin polymerizing factor 0.233497
ANAPC7 anaphase promoting complex subunit 7 0.233497
CAPS2 calcyphosine 2 0.233497
IFT43 intraflagellar transport 43 0.233497
MEAF6 MYST/Esa1-associated factor 6 0.233497
C7ORF43 chromosome 7 open reading frame 43 0.233497
ZNF112 zinc finger protein 112 0.233497
C2ORF74 chromosome 2 open reading frame 74 0.233497
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.233497
LAS1L LAS1-like (S. cerevisiae) 0.233497
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.233497
DCAF13 DDB1 and CUL4 associated factor 13 0.233497
ZNF408 zinc finger protein 408 0.233497
GNB5 guanine nucleotide binding protein (G protein), beta 5 0.233497
RIOK3 RIO kinase 3 0.233497
MMP15 matrix metallopeptidase 15 (membrane-inserted) 0.233497
PXN paxillin 0.233497
KCTD4 potassium channel tetramerization domain containing 4 0.233497
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 0.233497
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae) 0.233497
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.233497
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 0.233497
ENKD1 enkurin domain containing 1 0.233497
PXK PX domain containing serine/threonine kinase 0.233497
PDE8B phosphodiesterase 8B 0.233497
TET1 tet methylcytosine dioxygenase 1 0.233497
VLDLR very low density lipoprotein receptor 0.233497
HARBI1 harbinger transposase derived 1 0.233497
UBASH3B ubiquitin associated and SH3 domain containing B 0.233497
TMEM132C transmembrane protein 132C 0.233497
RBM39 RNA binding motif protein 39 0.233497
ANKRD45 ankyrin repeat domain 45 0.233497
CENPU centromere protein U 0.233497
EXOC6 exocyst complex component 6 0.233497
TLN1 talin 1 0.233497
DHRS1 dehydrogenase/reductase (SDR family) member 1 0.233497
ELL2 elongation factor, RNA polymerase II, 2 0.233497
TRAF3 TNF receptor-associated factor 3 0.233497
EYA2 EYA transcriptional coactivator and phosphatase 2 0.233497
EYA4 EYA transcriptional coactivator and phosphatase 4 0.233497
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 0.233497
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.233497
SYTL4 synaptotagmin-like 4 0.233497
CCDC57 coiled-coil domain containing 57 0.233497
GP1BA glycoprotein Ib (platelet), alpha polypeptide 0.233497
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.233497
CNTROB centrobin, centrosomal BRCA2 interacting protein 0.233497
ALPK1 alpha-kinase 1 0.233497
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 0.233497
ARHGAP29 Rho GTPase activating protein 29 0.233497
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.233497
ADNP activity-dependent neuroprotector homeobox 0.233497
CUEDC1 CUE domain containing 1 0.233497
TCEA2 transcription elongation factor A (SII), 2 0.233497
SMAD7 SMAD family member 7 0.233497
ZNF701 zinc finger protein 701 0.233497
ANKAR ankyrin and armadillo repeat containing 0.233497
VANGL1 VANGL planar cell polarity protein 1 0.233497
AURKA aurora kinase A 0.233497
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.233497
CPE carboxypeptidase E 0.233497
PDGFA platelet-derived growth factor alpha polypeptide 0.233497
ARL6IP6 ADP-ribosylation factor-like 6 interacting protein 6 0.233497
CD82 CD82 molecule 0.233497
TRPM2 transient receptor potential cation channel, subfamily M, member 2 0.233497
NCAPG non-SMC condensin I complex, subunit G 0.233497
APOL6 apolipoprotein L, 6 0.233497
ZC3H8 zinc finger CCCH-type containing 8 0.233497
USP37 ubiquitin specific peptidase 37 0.233497
NAE1 NEDD8 activating enzyme E1 subunit 1 0.233497
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.233497
PACRGL PARK2 co-regulated-like 0.233497
RPIA ribose 5-phosphate isomerase A 0.233497
FNIP2 folliculin interacting protein 2 0.233497
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.233497
TRDMT1 tRNA aspartic acid methyltransferase 1 0.233497
CEP350 centrosomal protein 350kDa 0.233497