microtubule plus-end Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The growing (plus) end of a microtubule. In vitro, microtubules polymerize more quickly at the plus end than at the minus end. In vivo, microtubule growth occurs only at the plus end, and the plus end switches between periods of growth and shortening, a behavior known as dynamic instability. (Gene Ontology, GO_0035371)
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Genes

126 proteins co-occuring with the microtubule plus-end cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CLIP1 CAP-GLY domain containing linker protein 1 2.66032
DCTN1 dynactin 1 1.78583
CLASP2 cytoplasmic linker associated protein 2 1.65693
CLASP1 cytoplasmic linker associated protein 1 1.39851
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 1.28143
MTUS2 microtubule associated tumor suppressor candidate 2 1.23296
MAPRE1 microtubule-associated protein, RP/EB family, member 1 1.23296
FYCO1 FYVE and coiled-coil domain containing 1 1.19108
CENPE centromere protein E, 312kDa 1.14085
CKAP5 cytoskeleton associated protein 5 1.10256
SLAIN2 SLAIN motif family, member 2 1.08019
APC adenomatous polyposis coli 1.02729
SLAIN1 SLAIN motif family, member 1 0.989759
MAPRE3 microtubule-associated protein, RP/EB family, member 3 0.922791
PDE4DIP phosphodiesterase 4D interacting protein 0.897646
MAPRE2 microtubule-associated protein, RP/EB family, member 2 0.865826
KIF1B kinesin family member 1B 0.844696
KIF7 kinesin family member 7 0.819452
KIFAP3 kinesin-associated protein 3 0.813028
DCTN2 dynactin 2 (p50) 0.801104
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 0.798353
CLUH clustered mitochondria (cluA/CLU1) homolog 0.787359
KIF2A kinesin heavy chain member 2A 0.776384
KIF1A kinesin family member 1A 0.770907
KIF11 kinesin family member 11 0.769995
NAV1 neuron navigator 1 0.76726
KIF20B kinesin family member 20B 0.746833
FMN1 formin 1 0.741867
TUBA1A tubulin, alpha 1a 0.739163
BICD2 bicaudal D homolog 2 (Drosophila) 0.725705
NAV3 neuron navigator 3 0.713682
KIF18A kinesin family member 18A 0.711908
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.707924
APOPT1 apoptogenic 1, mitochondrial 0.68639
MAP4 microtubule-associated protein 4 0.680719
SRCIN1 SRC kinase signaling inhibitor 1 0.675934
KIF4A kinesin family member 4A 0.671593
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 0.652159
DNAH12 dynein, axonemal, heavy chain 12 0.637578
DNAH14 dynein, axonemal, heavy chain 14 0.637578
KLHL2 kelch-like family member 2 0.630318
SPIRE2 spire-type actin nucleation factor 2 0.621804
DNAH5 dynein, axonemal, heavy chain 5 0.608241
AURKB aurora kinase B 0.604017
CSNK2A2 casein kinase 2, alpha prime polypeptide 0.603596
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.601487
STIM1 stromal interaction molecule 1 0.59896
KIF3A kinesin family member 3A 0.583431
FAT2 FAT atypical cadherin 2 0.563847
CENPH centromere protein H 0.54936
FIGN fidgetin 0.546885
GTSE1 G-2 and S-phase expressed 1 0.54606
DNAH9 dynein, axonemal, heavy chain 9 0.545236
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3 0.537416
CEP97 centrosomal protein 97kDa 0.534951
KIF3C kinesin family member 3C 0.529208
KIF2C kinesin family member 2C 0.52716
CENPQ centromere protein Q 0.520206
MACF1 microtubule-actin crosslinking factor 1 0.507977
KANK1 KN motif and ankyrin repeat domains 1 0.505944
KIF22 kinesin family member 22 0.503506
TACC3 transforming, acidic coiled-coil containing protein 3 0.503099
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 0.498231
NUMA1 nuclear mitotic apparatus protein 1 0.492966
EIF3K eukaryotic translation initiation factor 3, subunit K 0.484886
IQGAP1 IQ motif containing GTPase activating protein 1 0.484886
ITGB1BP1 integrin beta 1 binding protein 1 0.482064
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 0.479245
KIF1C kinesin family member 1C 0.461599
MLPH melanophilin 0.451233
PRC1 protein regulator of cytokinesis 1 0.448054
MAPT microtubule-associated protein tau 0.438542
USP15 ubiquitin specific peptidase 15 0.428678
KIF13B kinesin family member 13B 0.425531
SGOL2 shugoshin-like 2 (S. pombe) 0.424353
CNTROB centrobin, centrosomal BRCA2 interacting protein 0.41221
KRIT1 KRIT1, ankyrin repeat containing 0.409089
KIF3B kinesin family member 3B 0.400139
MYO5A myosin VA (heavy chain 12, myoxin) 0.397423
PLK1 polo-like kinase 1 0.390455
RAB27A RAB27A, member RAS oncogene family 0.390455
MAP2 microtubule-associated protein 2 0.383124
MCRS1 microspherule protein 1 0.376202
BCAS2 breast carcinoma amplified sequence 2 0.374283
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.369301
AKAP9 A kinase (PRKA) anchor protein 9 0.368536
DIAPH2 diaphanous-related formin 2 0.363185
SPAG5 sperm associated antigen 5 0.362804
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 0.361277
KIF5B kinesin family member 5B 0.360515
TUBA1C tubulin, alpha 1c 0.357847
SUFU suppressor of fused homolog (Drosophila) 0.341151
EML1 echinoderm microtubule associated protein like 1 0.340773
MAP1B microtubule-associated protein 1B 0.338128
CDK5RAP2 CDK5 regulatory subunit associated protein 2 0.326829
FMN2 formin 2 0.318205
PARD6A par-6 family cell polarity regulator alpha 0.317082
PRKCA protein kinase C, alpha 0.313718
BLOC1S2 biogenesis of lysosomal organelles complex-1, subunit 2 0.303655
GAS2 growth arrest-specific 2 0.299197
ZYX zyxin 0.275936
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.25438
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.252564
SYTL4 synaptotagmin-like 4 0.251476
NUF2 NUF2, NDC80 kinetochore complex component 0.240636
NMS neuromedin S 0.234891
TPPP tubulin polymerization promoting protein 0.233817
BICD1 bicaudal D homolog 1 (Drosophila) 0.229176
KTN1 kinectin 1 (kinesin receptor) 0.229176
CNTLN centlein, centrosomal protein 0.224204
NDEL1 nudE neurodevelopment protein 1-like 1 0.208137
AMPD2 adenosine monophosphate deaminase 2 0.204718
SIAH1 siah E3 ubiquitin protein ligase 1 0.199993
TTL tubulin tyrosine ligase 0.199659
BRWD1 bromodomain and WD repeat domain containing 1 0.19601
ATXN1 ataxin 1 0.195025
PDZK1 PDZ domain containing 1 0.18796
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 0.183935
MYO10 myosin X 0.182422
SCN4A sodium channel, voltage gated, type IV alpha subunit 0.179459
CDC42 cell division cycle 42 0.175745
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 0.174635
IGF2R insulin-like growth factor 2 receptor 0.172201
CASC5 cancer susceptibility candidate 5 0.170371
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 0.160863
NDC80 NDC80 kinetochore complex component 0.159462