microtubule Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. (Gene Ontology, GO_0005874)
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Genes

340 genes co-occuring with the biological term microtubule in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADAP1 ArfGAP with dual PH domains 1
ADIPOQ adiponectin, C1Q and collagen domain containing
AGBL2 ATP/GTP binding protein-like 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKAP9 A kinase (PRKA) anchor protein 9
AMER2 APC membrane recruitment protein 2
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
APC adenomatous polyposis coli
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AQP5 aquaporin 5
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARL2 ADP-ribosylation factor-like 2
ARR3 arrestin 3, retinal (X-arrestin)
ARRB2 arrestin, beta 2
ATAT1 alpha tubulin acetyltransferase 1
ATL1 atlastin GTPase 1
AURKA aurora kinase A
AURKB aurora kinase B
AXIN1 axin 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BICD1 bicaudal D homolog 1 (Drosophila)
BIN1 bridging integrator 1
BIRC5 baculoviral IAP repeat containing 5
BRCA1 breast cancer 1, early onset
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALU calumenin
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCAR1 cell division cycle and apoptosis regulator 1
CCDC8 coiled-coil domain containing 8
CCNA2 cyclin A2
CCNB1 cyclin B1
CD28 CD28 molecule
CD46 CD46 molecule, complement regulatory protein
CDC14B cell division cycle 14B
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CENPE centromere protein E, 312kDa
CENPF centromere protein F, 350/400kDa
CENPJ centromere protein J
CENPU centromere protein U
CEP126 centrosomal protein 126kDa
CEP192 centrosomal protein 192kDa
CEP350 centrosomal protein 350kDa
CEP57 centrosomal protein 57kDa
CEP70 centrosomal protein 70kDa
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CHMP1B charged multivesicular body protein 1B
CIB1 calcium and integrin binding 1 (calmyrin)
CKAP2 cytoskeleton associated protein 2
CKAP5 cytoskeleton associated protein 5
CLASP1 cytoplasmic linker associated protein 1
CLASP2 cytoplasmic linker associated protein 2
CLIP1 CAP-GLY domain containing linker protein 1
CLN3 ceroid-lipofuscinosis, neuronal 3
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CNTROB centrobin, centrosomal BRCA2 interacting protein
COMT catechol-O-methyltransferase
CRYAB crystallin, alpha B
CSNK1D casein kinase 1, delta
CSNK2B casein kinase 2, beta polypeptide
CSPP1 centrosome and spindle pole associated protein 1
CTGF connective tissue growth factor
CUL7 cullin 7
CYLD cylindromatosis (turban tumor syndrome)
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DCTN1 dynactin 1
DCX doublecortin
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DIAPH1 diaphanous-related formin 1
DIAPH3 diaphanous-related formin 3
DISC1 disrupted in schizophrenia 1
DLG1 discs, large homolog 1 (Drosophila)
DNAH12 dynein, axonemal, heavy chain 12
DSN1 DSN1, MIS12 kinetochore complex component
DSP desmoplakin
DST dystonin
DUSP9 dual specificity phosphatase 9
DVL1 dishevelled segment polarity protein 1
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DYNLL1 dynein, light chain, LC8-type 1
DYNLT1 dynein, light chain, Tctex-type 1
EGR1 early growth response 1
ELMO2 engulfment and cell motility 2
EML4 echinoderm microtubule associated protein like 4
EPB41 erythrocyte membrane protein band 4.1
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
FAM110B family with sequence similarity 110, member B
FAM161A family with sequence similarity 161, member A
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGFR1OP FGFR1 oncogene partner
FRY furry homolog (Drosophila)
G6PD glucose-6-phosphate dehydrogenase
GADD45A growth arrest and DNA-damage-inducible, alpha
GAK cyclin G associated kinase
GAN gigaxonin
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GOLGA4 golgin A4
GPN1 GPN-loop GTPase 1
GPSM2 G-protein signaling modulator 2
GRK5 G protein-coupled receptor kinase 5
GSK3B glycogen synthase kinase 3 beta
GTSE1 G-2 and S-phase expressed 1
HAUS6 HAUS augmin-like complex, subunit 6
HAUS8 HAUS augmin-like complex, subunit 8
HDAC6 histone deacetylase 6
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HOOK1 hook microtubule-tethering protein 1
HOOK2 hook microtubule-tethering protein 2
HSPA1A heat shock 70kDa protein 1A
HSPB1 heat shock 27kDa protein 1
HTRA1 HtrA serine peptidase 1
HTT huntingtin
ICAM1 intercellular adhesion molecule 1
IFT54 intraflagellar transport 54
IGK immunoglobulin kappa locus
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL1B interleukin 1, beta
IL6 interleukin 6
ILK integrin-linked kinase
INF2 inverted formin, FH2 and WH2 domain containing
INO80 INO80 complex subunit
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JPH2 junctophilin 2
KAT2B K(lysine) acetyltransferase 2B
KATNA1 katanin p60 (ATPase containing) subunit A 1
KATNAL1 katanin p60 subunit A-like 1
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KIF11 kinesin family member 11
KIF13A kinesin family member 13A
KIF16B kinesin family member 16B
KIF18A kinesin family member 18A
KIF18B kinesin family member 18B
KIF1C kinesin family member 1C
KIF20A kinesin family member 20A
KIF23 kinesin family member 23
KIF2A kinesin heavy chain member 2A
KIF2B kinesin family member 2B
KIF2C kinesin family member 2C
KIF4A kinesin family member 4A
KIF5B kinesin family member 5B
KIFC1 kinesin family member C1
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLC4 kinesin light chain 4
KNSTRN kinetochore-localized astrin/SPAG5 binding protein
KTN1 kinectin 1 (kinesin receptor)
LAT linker for activation of T cells
LATS1 large tumor suppressor kinase 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LDLR low density lipoprotein receptor
LIMK1 LIM domain kinase 1
LMNB1 lamin B1
LMNB2 lamin B2
LRRK2 leucine-rich repeat kinase 2
LZTS2 leucine zipper, putative tumor suppressor 2
MACF1 microtubule-actin crosslinking factor 1
MAL mal, T-cell differentiation protein
MAP10 microtubule-associated protein 10
MAP1B microtubule-associated protein 1B
MAP1S microtubule-associated protein 1S
MAP2 microtubule-associated protein 2
MAP4 microtubule-associated protein 4
MAP6 microtubule-associated protein 6
MAP7D3 MAP7 domain containing 3
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MAPT microtubule-associated protein tau
MARK1 MAP/microtubule affinity-regulating kinase 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MCL1 myeloid cell leukemia 1
MCRS1 microspherule protein 1
MECP2 methyl CpG binding protein 2
MEFV Mediterranean fever
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MISP mitotic spindle positioning
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MSN moesin
MST1R macrophage stimulating 1 receptor
MTUS1 microtubule associated tumor suppressor 1
MTUS2 microtubule associated tumor suppressor candidate 2
MYH9 myosin, heavy chain 9, non-muscle
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MZT2A mitotic spindle organizing protein 2A
NDC80 NDC80 kinetochore complex component
NDEL1 nudE neurodevelopment protein 1-like 1
NDRG1 N-myc downstream regulated 1
NEDD1 neural precursor cell expressed, developmentally down-regulated 1
NEK1 NIMA-related kinase 1
NEK2 NIMA-related kinase 2
NEK4 NIMA-related kinase 4
NEK7 NIMA-related kinase 7
NF2 neurofibromin 2 (merlin)
NGF nerve growth factor (beta polypeptide)
NIN ninein (GSK3B interacting protein)
NME7 NME/NM23 family member 7
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NUDC nudC nuclear distribution protein
NUF2 NUF2, NDC80 kinetochore complex component
NUMA1 nuclear mitotic apparatus protein 1
NUP107 nucleoporin 107kDa
NUP160 nucleoporin 160kDa
NUSAP1 nucleolar and spindle associated protein 1
OBSL1 obscurin-like 1
ODF2 outer dense fiber of sperm tails 2
OFD1 oral-facial-digital syndrome 1
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7
PCM1 pericentriolar material 1
PCNT pericentrin
PEBP1 phosphatidylethanolamine binding protein 1
PGR progesterone receptor
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHLDB2 pleckstrin homology-like domain, family B, member 2
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIP prolactin-induced protein
PLEC plectin
PLK1 polo-like kinase 1
PLK3 polo-like kinase 3
PPP4C protein phosphatase 4, catalytic subunit
PRC1 protein regulator of cytokinesis 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCD protein kinase C, delta
PRKD1 protein kinase D1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRNP prion protein
PSRC1 proline/serine-rich coiled-coil 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PXN paxillin
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RACGAP1 Rac GTPase activating protein 1
RAN RAN, member RAS oncogene family
RANBP1 RAN binding protein 1
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
REEP1 receptor accessory protein 1
RHOA ras homolog family member A
RND1 Rho family GTPase 1
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPGR retinitis pigmentosa GTPase regulator
RPS3 ribosomal protein S3
RS1 retinoschisin 1
RUVBL1 RuvB-like AAA ATPase 1
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SEPT2 septin 2
SEPT6 septin 6
SEPT7 septin 7
SGK1 serum/glucocorticoid regulated kinase 1
SGOL1 shugoshin-like 1 (S. pombe)
SIRT2 sirtuin 2
SIRT3 sirtuin 3
SKA1 spindle and kinetochore associated complex subunit 1
SKA3 spindle and kinetochore associated complex subunit 3
SLAIN2 SLAIN motif family, member 2
SLK STE20-like kinase
SMAD7 SMAD family member 7
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNAPIN SNAP-associated protein
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOCS3 suppressor of cytokine signaling 3
SPAG5 sperm associated antigen 5
SPAST spastin
SPEF1 sperm flagellar 1
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPIN1 spindlin 1
SQSTM1 sequestosome 1
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SSRP1 structure specific recognition protein 1
STARD9 StAR-related lipid transfer (START) domain containing 9
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STIM1 stromal interaction molecule 1
STK11 serine/threonine kinase 11
STMN1 stathmin 1
STMN2 stathmin 2
STRN striatin, calmodulin binding protein
SYMPK symplekin
SYNE1 spectrin repeat containing, nuclear envelope 1
TACC3 transforming, acidic coiled-coil containing protein 3
TAOK1 TAO kinase 1
TBC1D3 TBC1 domain family, member 3
TBCB tubulin folding cofactor B
TBCC tubulin folding cofactor C
TBCD tubulin folding cofactor D
TBCE tubulin folding cofactor E
TCHP trichoplein, keratin filament binding
TGFBR1 transforming growth factor, beta receptor 1
TNF tumor necrosis factor
TOR1A torsin family 1, member A (torsin A)
TP53 tumor protein p53
TPPP tubulin polymerization promoting protein
TPX2 TPX2, microtubule-associated
TRIM21 tripartite motif containing 21
TRIP10 thyroid hormone receptor interactor 10
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSLP thymic stromal lymphopoietin
TTK TTK protein kinase
TUBA4A tubulin, alpha 4a
TUBB tubulin, beta class I
TUBB1 tubulin, beta 1 class VI
TUBB3 tubulin, beta 3 class III
TUBE1 tubulin, epsilon 1
TXLNA taxilin alpha
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
USO1 USO1 vesicle transport factor
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIM vimentin
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta