midecamycin-1526 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the midecamycin-1526 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGER advanced glycosylation end product-specific receptor
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARHGAP26 Rho GTPase activating protein 26
ASAP1-IT1 ASAP1 intronic transcript 1
ASIC1 acid sensing (proton gated) ion channel 1
AUTS2 autism susceptibility candidate 2
BCAM basal cell adhesion molecule (Lutheran blood group)
C1ORF54 chromosome 1 open reading frame 54
C21ORF2 chromosome 21 open reading frame 2
C2ORF54 chromosome 2 open reading frame 54
C3AR1 complement component 3a receptor 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCR4 chemokine (C-C motif) receptor 4
CD8A CD8a molecule
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEP164 centrosomal protein 164kDa
CEP290 centrosomal protein 290kDa
CERS4 ceramide synthase 4
CFLAR CASP8 and FADD-like apoptosis regulator
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DPF3 D4, zinc and double PHD fingers, family 3
DUSP4 dual specificity phosphatase 4
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EPS8L1 EPS8-like 1
ERC1 ELKS/RAB6-interacting/CAST family member 1
EXOSC2 exosome component 2
FAM169A family with sequence similarity 169, member A
FASTKD2 FAST kinase domains 2
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FGF17 fibroblast growth factor 17
FOXG1 forkhead box G1
GPR143 G protein-coupled receptor 143
GPR153 G protein-coupled receptor 153
GUSBP3 glucuronidase, beta pseudogene 3
IL20RA interleukin 20 receptor, alpha
IL6ST interleukin 6 signal transducer
ISG20 interferon stimulated exonuclease gene 20kDa
JUN jun proto-oncogene
KIAA1456 KIAA1456
LPXN leupaxin
MARK4 MAP/microtubule affinity-regulating kinase 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFAP3L microfibrillar-associated protein 3-like
MSL3 male-specific lethal 3 homolog (Drosophila)
MTA1 metastasis associated 1
N4BP1 NEDD4 binding protein 1
N4BP3 NEDD4 binding protein 3
NEK1 NIMA-related kinase 1
NEK9 NIMA-related kinase 9
NF1 neurofibromin 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NOVA2 neuro-oncological ventral antigen 2
NPC1 Niemann-Pick disease, type C1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NXPH4 neurexophilin 4
OR10J1 olfactory receptor, family 10, subfamily J, member 1
PADI1 peptidyl arginine deiminase, type I
PCDH1 protocadherin 1
PLAA phospholipase A2-activating protein
PLK3 polo-like kinase 3
POU2F3 POU class 2 homeobox 3
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PTN pleiotrophin
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBM34 RNA binding motif protein 34
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
REM1 RAS (RAD and GEM)-like GTP-binding 1
RIMS2 regulating synaptic membrane exocytosis 2
RTN2 reticulon 2
SCAI suppressor of cancer cell invasion
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SEC14L2 SEC14-like 2 (S. cerevisiae)
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC46A3 solute carrier family 46, member 3
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SND1-IT1 SND1 intronic transcript 1
SOCS6 suppressor of cytokine signaling 6
SOX9 SRY (sex determining region Y)-box 9
SRRT serrate, RNA effector molecule
SRSF7 serine/arginine-rich splicing factor 7
SYNJ2 synaptojanin 2
TBRG4 transforming growth factor beta regulator 4
TBX6 T-box 6
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
VAC14 Vac14 homolog (S. cerevisiae)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
WIPF1 WAS/WASL interacting protein family, member 1
WSB1 WD repeat and SOCS box containing 1
ZNF226 zinc finger protein 226

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ACAD10 acyl-CoA dehydrogenase family, member 10
ADM adrenomedullin
AFF4 AF4/FMR2 family, member 4
ALPK1 alpha-kinase 1
ALS2CL ALS2 C-terminal like
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARC activity-regulated cytoskeleton-associated protein
ARL15 ADP-ribosylation factor-like 15
ART1 ADP-ribosyltransferase 1
ASB9 ankyrin repeat and SOCS box containing 9
ASPHD1 aspartate beta-hydroxylase domain containing 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BBS10 Bardet-Biedl syndrome 10
C17ORF80 chromosome 17 open reading frame 80
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC186 coiled-coil domain containing 186
CCDC9 coiled-coil domain containing 9
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CGA glycoprotein hormones, alpha polypeptide
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CRLF1 cytokine receptor-like factor 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTNNBIP1 catenin, beta interacting protein 1
CTSV cathepsin V
CUL9 cullin 9
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
FBRS fibrosin
FOSL1 FOS-like antigen 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GALE UDP-galactose-4-epimerase
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPALPP1 GPALPP motifs containing 1
GRB7 growth factor receptor-bound protein 7
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HDAC5 histone deacetylase 5
HIST1H2AJ histone cluster 1, H2aj
ICK intestinal cell (MAK-like) kinase
IPO8 importin 8
KLHL25 kelch-like family member 25
LIME1 Lck interacting transmembrane adaptor 1
LIN7A lin-7 homolog A (C. elegans)
LOC390998 ribosomal protein L10 pseudogene
LOC730101 uncharacterized LOC730101
LRRC61 leucine rich repeat containing 61
MBTD1 mbt domain containing 1
MEFV Mediterranean fever
METTL16 methyltransferase like 16
MVP major vault protein
NDE1 nudE neurodevelopment protein 1
NKX3-2 NK3 homeobox 2
NLRX1 NLR family member X1
NPIPB3 nuclear pore complex interacting protein family, member B3
NUP62CL nucleoporin 62kDa C-terminal like
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PDCD5 programmed cell death 5
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PROCR protein C receptor, endothelial
PRR14L proline rich 14-like
RIBC2 RIB43A domain with coiled-coils 2
RPAP2 RNA polymerase II associated protein 2
RPL13P5 ribosomal protein L13 pseudogene 5
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SAV1 salvador family WW domain containing protein 1
SDC3 syndecan 3
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SP1 Sp1 transcription factor
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STK25 serine/threonine kinase 25
STRA6 stimulated by retinoic acid 6
SULT4A1 sulfotransferase family 4A, member 1
SUN2 Sad1 and UNC84 domain containing 2
TBX19 T-box 19
TCTN2 tectonic family member 2
TFF2 trefoil factor 2
TMCC2 transmembrane and coiled-coil domain family 2
TNS2 tensin 2
UBQLN4 ubiquilin 4
VASH1 vasohibin 1
VGF VGF nerve growth factor inducible
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB33 zinc finger and BTB domain containing 33
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF134 zinc finger protein 134
ZNF23 zinc finger protein 23
ZNF34 zinc finger protein 34
ZNF350 zinc finger protein 350
ZNF484 zinc finger protein 484
ZNF665 zinc finger protein 665
ZNF76 zinc finger protein 76