midecamycin-1943 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the midecamycin-1943 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ACLY ATP citrate lyase
ADAM8 ADAM metallopeptidase domain 8
ALDOB aldolase B, fructose-bisphosphate
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BEX4 brain expressed, X-linked 4
BMP7 bone morphogenetic protein 7
BPHL biphenyl hydrolase-like (serine hydrolase)
C17ORF62 chromosome 17 open reading frame 62
CA7 carbonic anhydrase VII
CACYBP calcyclin binding protein
CD58 CD58 molecule
CHN2 chimerin 2
CLIP2 CAP-GLY domain containing linker protein 2
COL6A1 collagen, type VI, alpha 1
COPS2 COP9 signalosome subunit 2
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DENND3 DENN/MADD domain containing 3
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
EIF4B eukaryotic translation initiation factor 4B
EPB41L2 erythrocyte membrane protein band 4.1-like 2
ETNK1 ethanolamine kinase 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM63A family with sequence similarity 63, member A
FBXO31 F-box protein 31
FHL3 four and a half LIM domains 3
FOSL2 FOS-like antigen 2
FSD1 fibronectin type III and SPRY domain containing 1
GFOD2 glucose-fructose oxidoreductase domain containing 2
GLP1R glucagon-like peptide 1 receptor
GPR27 G protein-coupled receptor 27
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HK2 hexokinase 2
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HYAL2 hyaluronoglucosaminidase 2
ICAM1 intercellular adhesion molecule 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INO80B INO80 complex subunit B
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KLF11 Kruppel-like factor 11
KPNB1 karyopherin (importin) beta 1
KRT6A keratin 6A, type II
KYNU kynureninase
LAMP1 lysosomal-associated membrane protein 1
LIMK1 LIM domain kinase 1
LPPR2 lipid phosphate phosphatase-related protein type 2
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
LRP5 low density lipoprotein receptor-related protein 5
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MECP2 methyl CpG binding protein 2
MFSD11 major facilitator superfamily domain containing 11
MST1 macrophage stimulating 1
MYCBP MYC binding protein
MYO9B myosin IXB
NCKIPSD NCK interacting protein with SH3 domain
NKX3-1 NK3 homeobox 1
NOVA1 neuro-oncological ventral antigen 1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PARM1 prostate androgen-regulated mucin-like protein 1
PEX10 peroxisomal biogenesis factor 10
PEX12 peroxisomal biogenesis factor 12
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPAP2B phosphatidic acid phosphatase type 2B
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RAD50 RAD50 homolog (S. cerevisiae)
RGS4 regulator of G-protein signaling 4
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
SBNO2 strawberry notch homolog 2 (Drosophila)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SFTPB surfactant protein B
SIX2 SIX homeobox 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOD3 superoxide dismutase 3, extracellular
SOX13 SRY (sex determining region Y)-box 13
SYN2 synapsin II
TBC1D4 TBC1 domain family, member 4
TFG TRK-fused gene
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM97 transmembrane protein 97
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
U2AF2 U2 small nuclear RNA auxiliary factor 2
ZBED4 zinc finger, BED-type containing 4
ZNF286A zinc finger protein 286A
ZNF3 zinc finger protein 3
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ADAT1 adenosine deaminase, tRNA-specific 1
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
AHR aryl hydrocarbon receptor
ANKRD40 ankyrin repeat domain 40
ANXA2P3 annexin A2 pseudogene 3
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCL7C B-cell CLL/lymphoma 7C
BIN3 bridging integrator 3
BPGM 2,3-bisphosphoglycerate mutase
C17ORF70 chromosome 17 open reading frame 70
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
CAPNS1 calpain, small subunit 1
CD151 CD151 molecule (Raph blood group)
CENPM centromere protein M
CEP170B centrosomal protein 170B
CEP70 centrosomal protein 70kDa
CEP85 centrosomal protein 85kDa
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CLDND1 claudin domain containing 1
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CNIH4 cornichon family AMPA receptor auxiliary protein 4
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
DCTN5 dynactin 5 (p25)
DENND1B DENN/MADD domain containing 1B
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
ECD ecdysoneless homolog (Drosophila)
ELP3 elongator acetyltransferase complex subunit 3
ERMP1 endoplasmic reticulum metallopeptidase 1
FAF1 Fas (TNFRSF6) associated factor 1
FGD6 FYVE, RhoGEF and PH domain containing 6
FKBPL FK506 binding protein like
GBAS glioblastoma amplified sequence
GRAMD4 GRAM domain containing 4
GRM6 glutamate receptor, metabotropic 6
HELLS helicase, lymphoid-specific
HS1BP3 HCLS1 binding protein 3
ITGAV integrin, alpha V
JAM3 junctional adhesion molecule 3
KDM3A lysine (K)-specific demethylase 3A
KIN Kin17 DNA and RNA binding protein
LARP6 La ribonucleoprotein domain family, member 6
LYRM2 LYR motif containing 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAP6D1 MAP6 domain containing 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MEPCE methylphosphate capping enzyme
METTL18 methyltransferase like 18
METTL8 methyltransferase like 8
MRPL12 mitochondrial ribosomal protein L12
MT1HL1 metallothionein 1H-like 1
MX1 MX dynamin-like GTPase 1
NAP1L2 nucleosome assembly protein 1-like 2
NAP1L4 nucleosome assembly protein 1-like 4
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
PAK1IP1 PAK1 interacting protein 1
PBX3 pre-B-cell leukemia homeobox 3
PCNA proliferating cell nuclear antigen
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PNRC1 proline-rich nuclear receptor coactivator 1
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
RBM41 RNA binding motif protein 41
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RMI1 RecQ mediated genome instability 1
RNF220 ring finger protein 220
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
S100A6 S100 calcium binding protein A6
S100PBP S100P binding protein
SAP30L SAP30-like
SCML1 sex comb on midleg-like 1 (Drosophila)
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SHOC2 soc-2 suppressor of clear homolog (C. elegans)
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SSFA2 sperm specific antigen 2
STBD1 starch binding domain 1
TBC1D12 TBC1 domain family, member 12
TBPL1 TBP-like 1
TCTN1 tectonic family member 1
TICAM1 toll-like receptor adaptor molecule 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TM9SF2 transmembrane 9 superfamily member 2
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM62 transmembrane protein 62
TRAPPC6A trafficking protein particle complex 6A
TSPYL1 TSPY-like 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZNF430 zinc finger protein 430
ZNF580 zinc finger protein 580
ZNF91 zinc finger protein 91