| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the midecamycin-1943 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ABCG4 | ATP-binding cassette, sub-family G (WHITE), member 4 |
| ACLY | ATP citrate lyase |
| ADAM8 | ADAM metallopeptidase domain 8 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BEX4 | brain expressed, X-linked 4 |
| BMP7 | bone morphogenetic protein 7 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| C17ORF62 | chromosome 17 open reading frame 62 |
| CA7 | carbonic anhydrase VII |
| CACYBP | calcyclin binding protein |
| CD58 | CD58 molecule |
| CHN2 | chimerin 2 |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| COL6A1 | collagen, type VI, alpha 1 |
| COPS2 | COP9 signalosome subunit 2 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DENND3 | DENN/MADD domain containing 3 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 |
| EIF4B | eukaryotic translation initiation factor 4B |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 |
| ETNK1 | ethanolamine kinase 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM63A | family with sequence similarity 63, member A |
| FBXO31 | F-box protein 31 |
| FHL3 | four and a half LIM domains 3 |
| FOSL2 | FOS-like antigen 2 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GFOD2 | glucose-fructose oxidoreductase domain containing 2 |
| GLP1R | glucagon-like peptide 1 receptor |
| GPR27 | G protein-coupled receptor 27 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HK2 | hexokinase 2 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| HYAL2 | hyaluronoglucosaminidase 2 |
| ICAM1 | intercellular adhesion molecule 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| INO80B | INO80 complex subunit B |
| KCNJ14 | potassium channel, inwardly rectifying subfamily J, member 14 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KLF11 | Kruppel-like factor 11 |
| KPNB1 | karyopherin (importin) beta 1 |
| KRT6A | keratin 6A, type II |
| KYNU | kynureninase |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LIMK1 | LIM domain kinase 1 |
| LPPR2 | lipid phosphate phosphatase-related protein type 2 |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MECP2 | methyl CpG binding protein 2 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MST1 | macrophage stimulating 1 |
| MYCBP | MYC binding protein |
| MYO9B | myosin IXB |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NKX3-1 | NK3 homeobox 1 |
| NOVA1 | neuro-oncological ventral antigen 1 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PEX10 | peroxisomal biogenesis factor 10 |
| PEX12 | peroxisomal biogenesis factor 12 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) |
| RAD50 | RAD50 homolog (S. cerevisiae) |
| RGS4 | regulator of G-protein signaling 4 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SFTPB | surfactant protein B |
| SIX2 | SIX homeobox 2 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SOD3 | superoxide dismutase 3, extracellular |
| SOX13 | SRY (sex determining region Y)-box 13 |
| SYN2 | synapsin II |
| TBC1D4 | TBC1 domain family, member 4 |
| TFG | TRK-fused gene |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TMEM97 | transmembrane protein 97 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 |
| ZBED4 | zinc finger, BED-type containing 4 |
| ZNF286A | zinc finger protein 286A |
| ZNF3 | zinc finger protein 3 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
| AHR | aryl hydrocarbon receptor |
| ANKRD40 | ankyrin repeat domain 40 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BCL7C | B-cell CLL/lymphoma 7C |
| BIN3 | bridging integrator 3 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 |
| CAPNS1 | calpain, small subunit 1 |
| CD151 | CD151 molecule (Raph blood group) |
| CENPM | centromere protein M |
| CEP170B | centrosomal protein 170B |
| CEP70 | centrosomal protein 70kDa |
| CEP85 | centrosomal protein 85kDa |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 |
| CLDND1 | claudin domain containing 1 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 |
| COX16 | COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| DCTN5 | dynactin 5 (p25) |
| DENND1B | DENN/MADD domain containing 1B |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DNAJC22 | DnaJ (Hsp40) homolog, subfamily C, member 22 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| ECD | ecdysoneless homolog (Drosophila) |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 |
| FAF1 | Fas (TNFRSF6) associated factor 1 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FKBPL | FK506 binding protein like |
| GBAS | glioblastoma amplified sequence |
| GRAMD4 | GRAM domain containing 4 |
| GRM6 | glutamate receptor, metabotropic 6 |
| HELLS | helicase, lymphoid-specific |
| HS1BP3 | HCLS1 binding protein 3 |
| ITGAV | integrin, alpha V |
| JAM3 | junctional adhesion molecule 3 |
| KDM3A | lysine (K)-specific demethylase 3A |
| KIN | Kin17 DNA and RNA binding protein |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LYRM2 | LYR motif containing 2 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MAP6D1 | MAP6 domain containing 1 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MEPCE | methylphosphate capping enzyme |
| METTL18 | methyltransferase like 18 |
| METTL8 | methyltransferase like 8 |
| MRPL12 | mitochondrial ribosomal protein L12 |
| MT1HL1 | metallothionein 1H-like 1 |
| MX1 | MX dynamin-like GTPase 1 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NAP1L4 | nucleosome assembly protein 1-like 4 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 |
| PAK1IP1 | PAK1 interacting protein 1 |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PCNA | proliferating cell nuclear antigen |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 |
| RBM41 | RNA binding motif protein 41 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RMI1 | RecQ mediated genome instability 1 |
| RNF220 | ring finger protein 220 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RRN3 | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) |
| S100A6 | S100 calcium binding protein A6 |
| S100PBP | S100P binding protein |
| SAP30L | SAP30-like |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SSFA2 | sperm specific antigen 2 |
| STBD1 | starch binding domain 1 |
| TBC1D12 | TBC1 domain family, member 12 |
| TBPL1 | TBP-like 1 |
| TCTN1 | tectonic family member 1 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TM9SF2 | transmembrane 9 superfamily member 2 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM62 | transmembrane protein 62 |
| TRAPPC6A | trafficking protein particle complex 6A |
| TSPYL1 | TSPY-like 1 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| ZNF430 | zinc finger protein 430 |
| ZNF580 | zinc finger protein 580 |
| ZNF91 | zinc finger protein 91 |