| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the midecamycin-2026 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GNT | alpha-1,4-N-acetylglucosaminyltransferase |
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| AGTPBP1 | ATP/GTP binding protein 1 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| AQP8 | aquaporin 8 |
| ARL4D | ADP-ribosylation factor-like 4D |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 |
| BMP15 | bone morphogenetic protein 15 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C2 | complement component 2 |
| CACYBP | calcyclin binding protein |
| CARTPT | CART prepropeptide |
| CCS | copper chaperone for superoxide dismutase |
| CD58 | CD58 molecule |
| CDK13 | cyclin-dependent kinase 13 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma |
| CES2 | carboxylesterase 2 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 |
| CLTA | clathrin, light chain A |
| COMT | catechol-O-methyltransferase |
| CPNE7 | copine VII |
| CREBZF | CREB/ATF bZIP transcription factor |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| EDEM2 | ER degradation enhancer, mannosidase alpha-like 2 |
| EHD1 | EH-domain containing 1 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| FANCA | Fanconi anemia, complementation group A |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FCHO1 | FCH domain only 1 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GCAT | glycine C-acetyltransferase |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GPX2 | glutathione peroxidase 2 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit |
| HDAC5 | histone deacetylase 5 |
| HTT | huntingtin |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KIAA1109 | KIAA1109 |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LBP | lipopolysaccharide binding protein |
| LMCD1 | LIM and cysteine-rich domains 1 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MCC | mutated in colorectal cancers |
| MEPCE | methylphosphate capping enzyme |
| MOSPD2 | motile sperm domain containing 2 |
| MPHOSPH9 | M-phase phosphoprotein 9 |
| MPZL1 | myelin protein zero-like 1 |
| MZF1 | myeloid zinc finger 1 |
| N4BP1 | NEDD4 binding protein 1 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase |
| OR2C1 | olfactory receptor, family 2, subfamily C, member 1 |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor |
| PDCL | phosducin-like |
| PDE8A | phosphodiesterase 8A |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 |
| PDZD7 | PDZ domain containing 7 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRAMEF11 | PRAME family member 11 |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) |
| PTPRT | protein tyrosine phosphatase, receptor type, T |
| RPGR | retinitis pigmentosa GTPase regulator |
| SENP3 | SUMO1/sentrin/SMT3 specific peptidase 3 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SOCS2 | suppressor of cytokine signaling 2 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPECC1L | sperm antigen with calponin homology and coiled-coil domains 1-like |
| SRSF10 | serine/arginine-rich splicing factor 10 |
| TBC1D4 | TBC1 domain family, member 4 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| TMEM57 | transmembrane protein 57 |
| TMEM63A | transmembrane protein 63A |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TP53BP2 | tumor protein p53 binding protein 2 |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TRABD | TraB domain containing |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TTC3 | tetratricopeptide repeat domain 3 |
| TUBA4A | tubulin, alpha 4a |
| UBE2A | ubiquitin-conjugating enzyme E2A |
| UBE3A | ubiquitin protein ligase E3A |
| ULK1 | unc-51 like autophagy activating kinase 1 |
| WDR19 | WD repeat domain 19 |
| WDR61 | WD repeat domain 61 |
| WFS1 | Wolfram syndrome 1 (wolframin) |
| YIPF2 | Yip1 domain family, member 2 |
| ZFHX4 | zinc finger homeobox 4 |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF444 | zinc finger protein 444 |
| ZNF696 | zinc finger protein 696 |
| Symbol | Name |
|---|---|
| AIFM1 | apoptosis-inducing factor, mitochondrion-associated, 1 |
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 |
| APIP | APAF1 interacting protein |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa |
| ATP5I | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A |
| C14ORF166 | chromosome 14 open reading frame 166 |
| C1ORF27 | chromosome 1 open reading frame 27 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) |
| CBX3 | chromobox homolog 3 |
| CCDC59 | coiled-coil domain containing 59 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CDC45 | cell division cycle 45 |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 |
| CEPT1 | choline/ethanolamine phosphotransferase 1 |
| CNOT7 | CCR4-NOT transcription complex, subunit 7 |
| COMMD3 | COMM domain containing 3 |
| COMMD8 | COMM domain containing 8 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| CTR9 | CTR9, Paf1/RNA polymerase II complex component |
| DCTPP1 | dCTP pyrophosphatase 1 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
| ECHDC1 | ethylmalonyl-CoA decarboxylase 1 |
| EMP3 | epithelial membrane protein 3 |
| FAF1 | Fas (TNFRSF6) associated factor 1 |
| FAM111A | family with sequence similarity 111, member A |
| FAM46A | family with sequence similarity 46, member A |
| FAR2 | fatty acyl CoA reductase 2 |
| FRG1 | FSHD region gene 1 |
| FTH1P5 | ferritin, heavy polypeptide 1 pseudogene 5 |
| GABARAP | GABA(A) receptor-associated protein |
| GDE1 | glycerophosphodiester phosphodiesterase 1 |
| GMIP | GEM interacting protein |
| GPI | glucose-6-phosphate isomerase |
| GPN3 | GPN-loop GTPase 3 |
| GTF3C3 | general transcription factor IIIC, polypeptide 3, 102kDa |
| HIRA | histone cell cycle regulator |
| HMGB2 | high mobility group box 2 |
| HMGN3 | high mobility group nucleosomal binding domain 3 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B |
| HPS5 | Hermansky-Pudlak syndrome 5 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial |
| LASP1 | LIM and SH3 protein 1 |
| LBR | lamin B receptor |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MED17 | mediator complex subunit 17 |
| MFSD1 | major facilitator superfamily domain containing 1 |
| MRPL40 | mitochondrial ribosomal protein L40 |
| MTIF2 | mitochondrial translational initiation factor 2 |
| MTMR6 | myotubularin related protein 6 |
| MYL12B | myosin, light chain 12B, regulatory |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NACAP1 | nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 |
| NAE1 | NEDD8 activating enzyme E1 subunit 1 |
| NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa |
| NMI | N-myc (and STAT) interactor |
| NT5C2 | 5'-nucleotidase, cytosolic II |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 |
| PABPC3 | poly(A) binding protein, cytoplasmic 3 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 |
| PARK7 | parkinson protein 7 |
| PDCD6IP | programmed cell death 6 interacting protein |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POLR2G | polymerase (RNA) II (DNA directed) polypeptide G |
| POMP | proteasome maturation protein |
| PRMT1 | protein arginine methyltransferase 1 |
| PRPS2 | phosphoribosyl pyrophosphate synthetase 2 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 |
| RANBP6 | RAN binding protein 6 |
| RBMX | RNA binding motif protein, X-linked |
| RPL26 | ribosomal protein L26 |
| RPL30 | ribosomal protein L30 |
| RPL34 | ribosomal protein L34 |
| RPL36 | ribosomal protein L36 |
| RSL24D1 | ribosomal L24 domain containing 1 |
| SACS | sacsin molecular chaperone |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 |
| SLC38A2 | solute carrier family 38, member 2 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SNRPB2 | small nuclear ribonucleoprotein polypeptide B |
| SNX5 | sorting nexin 5 |
| SRP9 | signal recognition particle 9kDa |
| SUMO4 | small ubiquitin-like modifier 4 |
| TBK1 | TANK-binding kinase 1 |
| TBPL1 | TBP-like 1 |
| TM2D3 | TM2 domain containing 3 |
| TMBIM4 | transmembrane BAX inhibitor motif containing 4 |
| TMEM43 | transmembrane protein 43 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 |
| UTP11L | UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) |
| VDAC2 | voltage-dependent anion channel 2 |
| XPO1 | exportin 1 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) |
| ZCCHC8 | zinc finger, CCHC domain containing 8 |
| ZDHHC7 | zinc finger, DHHC-type containing 7 |
| ZWINT | ZW10 interacting kinetochore protein |
