| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the midecamycin-6745 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ACRV1 | acrosomal vesicle protein 1 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| AIRE | autoimmune regulator |
| ANGPTL2 | angiopoietin-like 2 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| BMPR1B | bone morphogenetic protein receptor, type IB |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CACYBP | calcyclin binding protein |
| CADM1 | cell adhesion molecule 1 |
| CCDC28B | coiled-coil domain containing 28B |
| CD93 | CD93 molecule |
| CHGA | chromogranin A |
| CHRNE | cholinergic receptor, nicotinic, epsilon (muscle) |
| COL10A1 | collagen, type X, alpha 1 |
| COL21A1 | collagen, type XXI, alpha 1 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| COMMD4 | COMM domain containing 4 |
| COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
| CYTH4 | cytohesin 4 |
| EDA | ectodysplasin A |
| EFNA5 | ephrin-A5 |
| EGR4 | early growth response 4 |
| FGG | fibrinogen gamma chain |
| FMOD | fibromodulin |
| FOXN2 | forkhead box N2 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| GAS7 | growth arrest-specific 7 |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GLRA2 | glycine receptor, alpha 2 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPATCH4 | G patch domain containing 4 |
| GPR21 | G protein-coupled receptor 21 |
| GUK1 | guanylate kinase 1 |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| IFFO1 | intermediate filament family orphan 1 |
| IL11 | interleukin 11 |
| KIF13A | kinesin family member 13A |
| KRAS | Kirsten rat sarcoma viral oncogene homolog |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LMOD1 | leiomodin 1 (smooth muscle) |
| LRRC17 | leucine rich repeat containing 17 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| LZTS1 | leucine zipper, putative tumor suppressor 1 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MST1L | macrophage stimulating 1-like |
| MT1M | metallothionein 1M |
| MVD | mevalonate (diphospho) decarboxylase |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic |
| NELL2 | NEL-like 2 (chicken) |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NRG1 | neuregulin 1 |
| OR7C1 | olfactory receptor, family 7, subfamily C, member 1 |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PCDHB3 | protocadherin beta 3 |
| PDLIM3 | PDZ and LIM domain 3 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) |
| PIGR | polymeric immunoglobulin receptor |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| POM121L9P | POM121 transmembrane nucleoporin-like 9, pseudogene |
| POU1F1 | POU class 1 homeobox 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRDM9 | PR domain containing 9 |
| PROM1 | prominin 1 |
| RAB30 | RAB30, member RAS oncogene family |
| RASSF4 | Ras association (RalGDS/AF-6) domain family member 4 |
| RBM12B | RNA binding motif protein 12B |
| RPS3A | ribosomal protein S3A |
| RQCD1 | RCD1 required for cell differentiation1 homolog (S. pombe) |
| RUNX1 | runt-related transcription factor 1 |
| SARDH | sarcosine dehydrogenase |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SP2 | Sp2 transcription factor |
| SRPK3 | SRSF protein kinase 3 |
| TBCD | tubulin folding cofactor D |
| THSD4 | thrombospondin, type I, domain containing 4 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TPM2 | tropomyosin 2 (beta) |
| TRD | T cell receptor delta locus |
| VDAC3 | voltage-dependent anion channel 3 |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZNF155 | zinc finger protein 155 |
| ZNF224 | zinc finger protein 224 |
| ZNF500 | zinc finger protein 500 |
| Symbol | Name |
|---|---|
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
| ADGRF1 | adhesion G protein-coupled receptor F1 |
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ARRB2 | arrestin, beta 2 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| AURKC | aurora kinase C |
| C11ORF63 | chromosome 11 open reading frame 63 |
| CASS4 | Cas scaffolding protein family member 4 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CHM | choroideremia (Rab escort protein 1) |
| CHMP6 | charged multivesicular body protein 6 |
| CLDN14 | claudin 14 |
| CNN1 | calponin 1, basic, smooth muscle |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DCSTAMP | dendrocyte expressed seven transmembrane protein |
| DMTN | dematin actin binding protein |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FAM188A | family with sequence similarity 188, member A |
| FAM50B | family with sequence similarity 50, member B |
| FOXA1 | forkhead box A1 |
| FRMD8 | FERM domain containing 8 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GOLGA8B | golgin A8 family, member B |
| HAMP | hepcidin antimicrobial peptide |
| HDAC11 | histone deacetylase 11 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXC4 | homeobox C4 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IPO8 | importin 8 |
| IQCG | IQ motif containing G |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KCTD3 | potassium channel tetramerization domain containing 3 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0319L | KIAA0319-like |
| KIAA0922 | KIAA0922 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| MANBA | mannosidase, beta A, lysosomal |
| MED15 | mediator complex subunit 15 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MICU1 | mitochondrial calcium uptake 1 |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MTSS1L | metastasis suppressor 1-like |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NEK11 | NIMA-related kinase 11 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PARPBP | PARP1 binding protein |
| PCYT1A | phosphate cytidylyltransferase 1, choline, alpha |
| PISD | phosphatidylserine decarboxylase |
| PLA2G15 | phospholipase A2, group XV |
| PLCD1 | phospholipase C, delta 1 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PRSS16 | protease, serine, 16 (thymus) |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTK6 | protein tyrosine kinase 6 |
| RAB5B | RAB5B, member RAS oncogene family |
| RHOB | ras homolog family member B |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SLC22A1 | solute carrier family 22 (organic cation transporter), member 1 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STX1A | syntaxin 1A (brain) |
| TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TGIF1 | TGFB-induced factor homeobox 1 |
| TLN1 | talin 1 |
| UBOX5 | U-box domain containing 5 |
| YOD1 | YOD1 deubiquitinase |
| YY2 | YY2 transcription factor |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF358 | zinc finger protein 358 |
| ZNF551 | zinc finger protein 551 |
| ZNF747 | zinc finger protein 747 |
| ZXDB | zinc finger, X-linked, duplicated B |