| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the midodrine-2250 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| AHNAK | AHNAK nucleoprotein |
| AIRE | autoimmune regulator |
| ARC | activity-regulated cytoskeleton-associated protein |
| ATG10 | autophagy related 10 |
| BLNK | B-cell linker |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| C1QB | complement component 1, q subcomponent, B chain |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CABIN1 | calcineurin binding protein 1 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CARD9 | caspase recruitment domain family, member 9 |
| CCNK | cyclin K |
| CD6 | CD6 molecule |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| COMT | catechol-O-methyltransferase |
| CPQ | carboxypeptidase Q |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DTNA | dystrobrevin, alpha |
| DUSP6 | dual specificity phosphatase 6 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| EVA1B | eva-1 homolog B (C. elegans) |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FH | fumarate hydratase |
| FHL1 | four and a half LIM domains 1 |
| FRMD4A | FERM domain containing 4A |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| GFAP | glial fibrillary acidic protein |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GRM7 | glutamate receptor, metabotropic 7 |
| H2AFX | H2A histone family, member X |
| HBEGF | heparin-binding EGF-like growth factor |
| HFE | hemochromatosis |
| HIST1H4E | histone cluster 1, H4e |
| HOXD1 | homeobox D1 |
| ITGA8 | integrin, alpha 8 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KIAA0125 | KIAA0125 |
| KIF25 | kinesin family member 25 |
| LAMC2 | laminin, gamma 2 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| MAP4 | microtubule-associated protein 4 |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MINK1 | misshapen-like kinase 1 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MLXIP | MLX interacting protein |
| MMP25 | matrix metallopeptidase 25 |
| MOBP | myelin-associated oligodendrocyte basic protein |
| MTCP1 | mature T-cell proliferation 1 |
| NEK1 | NIMA-related kinase 1 |
| NF2 | neurofibromin 2 (merlin) |
| NUP188 | nucleoporin 188kDa |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| OCLM | oculomedin |
| ONECUT2 | one cut homeobox 2 |
| PARD6B | par-6 family cell polarity regulator beta |
| PCDH9 | protocadherin 9 |
| PDCD2 | programmed cell death 2 |
| PHF1 | PHD finger protein 1 |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLXNB3 | plexin B3 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PRM1 | protamine 1 |
| PRX | periaxin |
| PXN | paxillin |
| RAP1GAP | RAP1 GTPase activating protein |
| RASAL2 | RAS protein activator like 2 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RND1 | Rho family GTPase 1 |
| RORC | RAR-related orphan receptor C |
| RUNX1 | runt-related transcription factor 1 |
| SEC24A | SEC24 family member A |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SFRP4 | secreted frizzled-related protein 4 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TOR4A | torsin family 4, member A |
| TP63 | tumor protein p63 |
| TPSG1 | tryptase gamma 1 |
| TRIM29 | tripartite motif containing 29 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| ZFHX2 | zinc finger homeobox 2 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZMAT4 | zinc finger, matrin-type 4 |
| ZNF235 | zinc finger protein 235 |
| ZNF480 | zinc finger protein 480 |
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| AHNAK2 | AHNAK nucleoprotein 2 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| AMPD1 | adenosine monophosphate deaminase 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APOLD1 | apolipoprotein L domain containing 1 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BCL9 | B-cell CLL/lymphoma 9 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CBX8 | chromobox homolog 8 |
| CCDC134 | coiled-coil domain containing 134 |
| CCDC25 | coiled-coil domain containing 25 |
| CCNJL | cyclin J-like |
| CD34 | CD34 molecule |
| CD83 | CD83 molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CEL | carboxyl ester lipase |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLDN1 | claudin 1 |
| CLSPN | claspin |
| CPNE7 | copine VII |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| DOK5 | docking protein 5 |
| EFNA3 | ephrin-A3 |
| FAM155A | family with sequence similarity 155, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FFAR2 | free fatty acid receptor 2 |
| FLCN | folliculin |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GATA4 | GATA binding protein 4 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GSTA4 | glutathione S-transferase alpha 4 |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H3E | histone cluster 1, H3e |
| HIST1H4A | histone cluster 1, H4a |
| HPX | hemopexin |
| IGSF1 | immunoglobulin superfamily, member 1 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| KLHL36 | kelch-like family member 36 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MAGOH2P | mago-nashi homolog 2, pseudogene |
| MYOZ1 | myozenin 1 |
| NOL12 | nucleolar protein 12 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NPTX1 | neuronal pentraxin I |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| OVOL1 | ovo-like zinc finger 1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCDHA6 | protocadherin alpha 6 |
| PITX2 | paired-like homeodomain 2 |
| PLA2G10 | phospholipase A2, group X |
| PODNL1 | podocan-like 1 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PP14571 | uncharacterized LOC100130449 |
| PQLC2 | PQ loop repeat containing 2 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB3A | RAB3A, member RAS oncogene family |
| RAB40C | RAB40C, member RAS oncogene family |
| RFPL1S | RFPL1 antisense RNA 1 |
| RNF2 | ring finger protein 2 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SEC14L5 | SEC14-like 5 (S. cerevisiae) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SIPA1 | signal-induced proliferation-associated 1 |
| SIRT2 | sirtuin 2 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| STAB2 | stabilin 2 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| TCTN1 | tectonic family member 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TSPAN2 | tetraspanin 2 |
| TTC30A | tetratricopeptide repeat domain 30A |
| UPK3B | uroplakin 3B |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VEGFC | vascular endothelial growth factor C |
| WDR33 | WD repeat domain 33 |
| WDR76 | WD repeat domain 76 |
| WFDC2 | WAP four-disulfide core domain 2 |
| XDH | xanthine dehydrogenase |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZIM2 | zinc finger, imprinted 2 |