| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the midodrine-7156 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| ARHGAP28 | Rho GTPase activating protein 28 |
| ATF5 | activating transcription factor 5 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
| AVL9 | AVL9 homolog (S. cerevisiase) |
| BAIAP2 | BAI1-associated protein 2 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| BSPRY | B-box and SPRY domain containing |
| BTN3A2 | butyrophilin, subfamily 3, member A2 |
| C16ORF58 | chromosome 16 open reading frame 58 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCPG1 | cell cycle progression 1 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| COL5A1 | collagen, type V, alpha 1 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DFNB31 | deafness, autosomal recessive 31 |
| DOHH | deoxyhypusine hydroxylase/monooxygenase |
| DRP2 | dystrophin related protein 2 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) |
| EPS8L1 | EPS8-like 1 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 |
| ERI3 | ERI1 exoribonuclease family member 3 |
| FAM13A | family with sequence similarity 13, member A |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GATA2 | GATA binding protein 2 |
| GK | glycerol kinase |
| GLI2 | GLI family zinc finger 2 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| H2AFX | H2A histone family, member X |
| HDAC9 | histone deacetylase 9 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HK2 | hexokinase 2 |
| HOXA6 | homeobox A6 |
| IL1RAP | interleukin 1 receptor accessory protein |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| IRAK3 | interleukin-1 receptor-associated kinase 3 |
| JAK2 | Janus kinase 2 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KRT34 | keratin 34, type I |
| LIMK1 | LIM domain kinase 1 |
| LMBR1L | limb development membrane protein 1-like |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MECP2 | methyl CpG binding protein 2 |
| MLH3 | mutL homolog 3 |
| MPI | mannose phosphate isomerase |
| MXRA8 | matrix-remodelling associated 8 |
| MYL10 | myosin, light chain 10, regulatory |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NLRX1 | NLR family member X1 |
| NUDCD3 | NudC domain containing 3 |
| OPRL1 | opiate receptor-like 1 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 |
| PDLIM5 | PDZ and LIM domain 5 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 |
| PLCD1 | phospholipase C, delta 1 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| RAB33B | RAB33B, member RAS oncogene family |
| RAD54B | RAD54 homolog B (S. cerevisiae) |
| RANBP3 | RAN binding protein 3 |
| SEC24D | SEC24 family member D |
| SEC63 | SEC63 homolog (S. cerevisiae) |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SSH3 | slingshot protein phosphatase 3 |
| TCF3 | transcription factor 3 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM212 | transmembrane protein 212 |
| TMF1 | TATA element modulatory factor 1 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| USP20 | ubiquitin specific peptidase 20 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF197 | zinc finger protein 197 |
| ZNF79 | zinc finger protein 79 |
| ZNF93 | zinc finger protein 93 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACTN4 | actinin, alpha 4 |
| ADCY7 | adenylate cyclase 7 |
| ADGRF1 | adhesion G protein-coupled receptor F1 |
| AEN | apoptosis enhancing nuclease |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C2ORF42 | chromosome 2 open reading frame 42 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCDC68 | coiled-coil domain containing 68 |
| CCDC69 | coiled-coil domain containing 69 |
| CCNJL | cyclin J-like |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLEC16A | C-type lectin domain family 16, member A |
| DCLRE1B | DNA cross-link repair 1B |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DGKD | diacylglycerol kinase, delta 130kDa |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| EAF2 | ELL associated factor 2 |
| ECI1 | enoyl-CoA delta isomerase 1 |
| EDC3 | enhancer of mRNA decapping 3 |
| EFNA4 | ephrin-A4 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EPPK1 | epiplakin 1 |
| ERCC2 | excision repair cross-complementation group 2 |
| ERF | Ets2 repressor factor |
| FAM155A | family with sequence similarity 155, member A |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| GAB2 | GRB2-associated binding protein 2 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GID4 | GID complex subunit 4 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPR4 | G protein-coupled receptor 4 |
| HIST1H1D | histone cluster 1, H1d |
| IFT54 | intraflagellar transport 54 |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KIAA0895 | KIAA0895 |
| LOC730101 | uncharacterized LOC730101 |
| MMP1 | matrix metallopeptidase 1 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| NCS1 | neuronal calcium sensor 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| OXR1 | oxidation resistance 1 |
| OXTR | oxytocin receptor |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 |
| POLM | polymerase (DNA directed), mu |
| PPCS | phosphopantothenoylcysteine synthetase |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PRMT7 | protein arginine methyltransferase 7 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PSPC1 | paraspeckle component 1 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| QTRTD1 | queuine tRNA-ribosyltransferase domain containing 1 |
| RAB3A | RAB3A, member RAS oncogene family |
| RBL1 | retinoblastoma-like 1 |
| RGS19 | regulator of G-protein signaling 19 |
| RPAP2 | RNA polymerase II associated protein 2 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCAI | suppressor of cancer cell invasion |
| SCAMP5 | secretory carrier membrane protein 5 |
| SDAD1 | SDA1 domain containing 1 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) |
| SETD6 | SET domain containing 6 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SNX10 | sorting nexin 10 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STK16 | serine/threonine kinase 16 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| THAP10 | THAP domain containing 10 |
| THBS3 | thrombospondin 3 |
| TMC5 | transmembrane channel-like 5 |
| TMEM38B | transmembrane protein 38B |
| TNS2 | tensin 2 |
| UBTD1 | ubiquitin domain containing 1 |
| UBXN2B | UBX domain protein 2B |
| USP39 | ubiquitin specific peptidase 39 |
| USP6NL | USP6 N-terminal like |
| VASH2 | vasohibin 2 |
| YOD1 | YOD1 deubiquitinase |
| ZBTB24 | zinc finger and BTB domain containing 24 |
| ZNF33B | zinc finger protein 33B |
| ZNF385D | zinc finger protein 385D |
| ZNF408 | zinc finger protein 408 |