mif Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description macrophage migration inhibitory factor (glycosylation-inhibiting factor)|This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4282)
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Genes

73 genes co-occuring with the biological term mif in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ADRBK1 adrenergic, beta, receptor kinase 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BNIPL BCL2/adenovirus E1B 19kD interacting protein like
BSG basigin (Ok blood group)
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
COPS5 COP9 signalosome subunit 5
CREB1 cAMP responsive element binding protein 1
CRP C-reactive protein, pentraxin-related
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DCT dopachrome tautomerase
DDT D-dopachrome tautomerase
EPAS1 endothelial PAS domain protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
GFER growth factor, augmenter of liver regeneration
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
GREM1 gremlin 1, DAN family BMP antagonist
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HBP1 HMG-box transcription factor 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HSF1 heat shock transcription factor 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IL17A interleukin 17A
IL17F interleukin 17F
IL1B interleukin 1, beta
IL6 interleukin 6
ITGAV integrin, alpha V
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JUN jun proto-oncogene
LEP leptin
MAPK14 mitogen-activated protein kinase 14
MBL2 mannose-binding lectin (protein C) 2, soluble
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR451A microRNA 451a
MMP1 matrix metallopeptidase 1
MMP9 matrix metallopeptidase 9
NAMPT nicotinamide phosphoribosyltransferase
NCOA3 nuclear receptor coactivator 3
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
PARK7 parkinson protein 7
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PTRF polymerase I and transcript release factor
RPS19 ribosomal protein S19
SOD2 superoxide dismutase 2, mitochondrial
SP1 Sp1 transcription factor
STK11 serine/threonine kinase 11
THBD thrombomodulin
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TP53 tumor protein p53
TP63 tumor protein p63
TXN thioredoxin
USO1 USO1 vesicle transport factor
VEGFA vascular endothelial growth factor A