mifepristone-1569 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the mifepristone-1569 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ACTC1 actin, alpha, cardiac muscle 1
ADGRA2 adhesion G protein-coupled receptor A2
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ANKMY1 ankyrin repeat and MYND domain containing 1
APP amyloid beta (A4) precursor protein
ATAD2B ATPase family, AAA domain containing 2B
ATG13 autophagy related 13
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
BICD1 bicaudal D homolog 1 (Drosophila)
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CCPG1 cell cycle progression 1
CENPF centromere protein F, 350/400kDa
CLIC4 chloride intracellular channel 4
CPOX coproporphyrinogen oxidase
CTH cystathionine gamma-lyase
CTSS cathepsin S
CTSZ cathepsin Z
DAPK1 death-associated protein kinase 1
DLX2 distal-less homeobox 2
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FAM153A family with sequence similarity 153, member A
FANCF Fanconi anemia, complementation group F
FASTK Fas-activated serine/threonine kinase
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GABPB1 GA binding protein transcription factor, beta subunit 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLS glutaminase
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GOLGA1 golgin A1
GOSR1 golgi SNAP receptor complex member 1
GRM6 glutamate receptor, metabotropic 6
GSAP gamma-secretase activating protein
GSK3A glycogen synthase kinase 3 alpha
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
JAG1 jagged 1
JRKL JRK-like
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KIFC1 kinesin family member C1
KIZ kizuna centrosomal protein
KLF10 Kruppel-like factor 10
KLF11 Kruppel-like factor 11
KPNB1 karyopherin (importin) beta 1
KRIT1 KRIT1, ankyrin repeat containing
LAD1 ladinin 1
LINC00339 long intergenic non-protein coding RNA 339
LRRC37A3 leucine rich repeat containing 37, member A3
LRRN2 leucine rich repeat neuronal 2
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAML3 mastermind-like 3 (Drosophila)
MBTD1 mbt domain containing 1
METTL5 methyltransferase like 5
MOCOS molybdenum cofactor sulfurase
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MPZL1 myelin protein zero-like 1
MT1E metallothionein 1E
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MX1 MX dynamin-like GTPase 1
N4BP2L2 NEDD4 binding protein 2-like 2
NCK1 NCK adaptor protein 1
NDRG2 NDRG family member 2
NPTXR neuronal pentraxin receptor
NRIP1 nuclear receptor interacting protein 1
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PBX2 pre-B-cell leukemia homeobox 2
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PKD1 polycystic kidney disease 1 (autosomal dominant)
PNOC prepronociceptin
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PRKCA protein kinase C, alpha
PRKX protein kinase, X-linked
PRPH peripherin
PTK2 protein tyrosine kinase 2
RP2 retinitis pigmentosa 2 (X-linked recessive)
SDC2 syndecan 2
SEC23B Sec23 homolog B (S. cerevisiae)
SH3BP2 SH3-domain binding protein 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SPATA5L1 spermatogenesis associated 5-like 1
SRR serine racemase
STK16 serine/threonine kinase 16
THADA thyroid adenoma associated
TMEM161A transmembrane protein 161A
TPI1 triosephosphate isomerase 1
TRAIP TRAF interacting protein
TRIM22 tripartite motif containing 22
UBOX5 U-box domain containing 5
UGDH UDP-glucose 6-dehydrogenase
USP20 ubiquitin specific peptidase 20
VEGFA vascular endothelial growth factor A
VILL villin-like
WIZ widely interspaced zinc finger motifs
ZBED1 zinc finger, BED-type containing 1
ZC3H7B zinc finger CCCH-type containing 7B
ZSCAN5A zinc finger and SCAN domain containing 5A

decreased expression

Symbol Name
AMT aminomethyltransferase
ARID5A AT rich interactive domain 5A (MRF1-like)
ASAP1-IT1 ASAP1 intronic transcript 1
ATG2A autophagy related 2A
BAK1 BCL2-antagonist/killer 1
BCL2L2 BCL2-like 2
BCL7B B-cell CLL/lymphoma 7B
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BIN2 bridging integrator 2
C1QTNF1 C1q and tumor necrosis factor related protein 1
C6ORF47 chromosome 6 open reading frame 47
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CCDC88C coiled-coil domain containing 88C
CCL2 chemokine (C-C motif) ligand 2
CD151 CD151 molecule (Raph blood group)
CD82 CD82 molecule
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
COG7 component of oligomeric golgi complex 7
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DBF4B DBF4 zinc finger B
DGKD diacylglycerol kinase, delta 130kDa
ELANE elastase, neutrophil expressed
EPX eosinophil peroxidase
ERCC2 excision repair cross-complementation group 2
FBRS fibrosin
FGL1 fibrinogen-like 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GALE UDP-galactose-4-epimerase
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GEMIN6 gem (nuclear organelle) associated protein 6
GPS1 G protein pathway suppressor 1
GPX4 glutathione peroxidase 4
GSDMD gasdermin D
HCAR3 hydroxycarboxylic acid receptor 3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMG20A high mobility group 20A
HRAS Harvey rat sarcoma viral oncogene homolog
IGBP1 immunoglobulin (CD79A) binding protein 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
LIN37 lin-37 DREAM MuvB core complex component
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MAPKBP1 mitogen-activated protein kinase binding protein 1
MCAT malonyl CoA:ACP acyltransferase (mitochondrial)
MCM10 minichromosome maintenance complex component 10
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MON1B MON1 secretory trafficking family member B
MPHOSPH8 M-phase phosphoprotein 8
MXRA8 matrix-remodelling associated 8
MYO19 myosin XIX
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NCF1C neutrophil cytosolic factor 1C pseudogene
OGFRL1 opioid growth factor receptor-like 1
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PISD phosphatidylserine decarboxylase
PNPLA6 patatin-like phospholipase domain containing 6
POM121 POM121 transmembrane nucleoporin
PRMT1 protein arginine methyltransferase 1
RAD54L RAD54-like (S. cerevisiae)
RBMS3 RNA binding motif, single stranded interacting protein 3
RHOF ras homolog family member F (in filopodia)
RPL13P5 ribosomal protein L13 pseudogene 5
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RRP1 ribosomal RNA processing 1
RSRC1 arginine/serine-rich coiled-coil 1
RUVBL2 RuvB-like AAA ATPase 2
SLC41A3 solute carrier family 41, member 3
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLPI secretory leukocyte peptidase inhibitor
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SNORA21 small nucleolar RNA, H/ACA box 21
SNX15 sorting nexin 15
SPEF1 sperm flagellar 1
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STARD3 StAR-related lipid transfer (START) domain containing 3
STX1A syntaxin 1A (brain)
STX5 syntaxin 5
SYT13 synaptotagmin XIII
TERT telomerase reverse transcriptase
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TM7SF3 transmembrane 7 superfamily member 3
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
UBA1 ubiquitin-like modifier activating enzyme 1
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
USP39 ubiquitin specific peptidase 39
WBSCR16 Williams-Beuren syndrome chromosome region 16
WDR46 WD repeat domain 46
ZNF426 zinc finger protein 426
ZNF721 zinc finger protein 721