mifepristone-3185 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the mifepristone-3185 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ACO2 aconitase 2, mitochondrial
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
ANGPTL2 angiopoietin-like 2
ANOS1 anosmin 1
APOBR apolipoprotein B receptor
ARHGAP26 Rho GTPase activating protein 26
ASIC1 acid sensing (proton gated) ion channel 1
CA3 carbonic anhydrase III
CA9 carbonic anhydrase IX
CACFD1 calcium channel flower domain containing 1
CAMP cathelicidin antimicrobial peptide
CCKAR cholecystokinin A receptor
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CES1 carboxylesterase 1
CST1 cystatin SN
CTSS cathepsin S
CYLD cylindromatosis (turban tumor syndrome)
DNAAF1 dynein, axonemal, assembly factor 1
DNAI2 dynein, axonemal, intermediate chain 2
DSPP dentin sialophosphoprotein
EFCAB11 EF-hand calcium binding domain 11
EMILIN1 elastin microfibril interfacer 1
FCAR Fc fragment of IgA receptor
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FSHB follicle stimulating hormone, beta polypeptide
FSTL1 follistatin-like 1
GAS2 growth arrest-specific 2
GEMIN7 gem (nuclear organelle) associated protein 7
GP1BB glycoprotein Ib (platelet), beta polypeptide
GRM6 glutamate receptor, metabotropic 6
GYPB glycophorin B (MNS blood group)
HEPH hephaestin
HIST1H3I histone cluster 1, H3i
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
ICA1 islet cell autoantigen 1, 69kDa
IDUA iduronidase, alpha-L-
IMPG1 interphotoreceptor matrix proteoglycan 1
ITM2A integral membrane protein 2A
IVL involucrin
KLHL22 kelch-like family member 22
KMT2A lysine (K)-specific methyltransferase 2A
KRT37 keratin 37, type I
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAMC2 laminin, gamma 2
LTBP2 latent transforming growth factor beta binding protein 2
MAPK10 mitogen-activated protein kinase 10
MBD2 methyl-CpG binding domain protein 2
MFGE8 milk fat globule-EGF factor 8 protein
MLANA melan-A
MLXIP MLX interacting protein
MMP2 matrix metallopeptidase 2
MOG myelin oligodendrocyte glycoprotein
MORC1 MORC family CW-type zinc finger 1
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
N4BP3 NEDD4 binding protein 3
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NR6A1 nuclear receptor subfamily 6, group A, member 1
NXPE4 neurexophilin and PC-esterase domain family, member 4
OSBPL3 oxysterol binding protein-like 3
OSGIN2 oxidative stress induced growth inhibitor family member 2
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PDE11A phosphodiesterase 11A
PDLIM3 PDZ and LIM domain 3
PLEK pleckstrin
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRAMEF10 PRAME family member 10
PRDM11 PR domain containing 11
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PWAR5 Prader Willi/Angelman region RNA 5
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RPL35A ribosomal protein L35a
RUSC2 RUN and SH3 domain containing 2
SCARF1 scavenger receptor class F, member 1
SLC6A16 solute carrier family 6, member 16
SMC1A structural maintenance of chromosomes 1A
SSTR5 somatostatin receptor 5
TAPBP TAP binding protein (tapasin)
TAT tyrosine aminotransferase
TBXAS1 thromboxane A synthase 1 (platelet)
TCF3 transcription factor 3
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TLR7 toll-like receptor 7
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRD T cell receptor delta locus
TSHZ2 teashirt zinc finger homeobox 2
TSPAN8 tetraspanin 8
TTTY2 testis-specific transcript, Y-linked 2 (non-protein coding)
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
WNT5A wingless-type MMTV integration site family, member 5A
WNT7A wingless-type MMTV integration site family, member 7A
ZNF415 zinc finger protein 415

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACAD8 acyl-CoA dehydrogenase family, member 8
ADAM15 ADAM metallopeptidase domain 15
ANKRD28 ankyrin repeat domain 28
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTBD2 BTB (POZ) domain containing 2
CCDC88C coiled-coil domain containing 88C
CCNL2 cyclin L2
CCNO cyclin O
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CINP cyclin-dependent kinase 2 interacting protein
CRYBG3 beta-gamma crystallin domain containing 3
CXCL12 chemokine (C-X-C motif) ligand 12
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DYSF dysferlin
EGLN3 egl-9 family hypoxia-inducible factor 3
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EXD3 exonuclease 3'-5' domain containing 3
FAIM Fas apoptotic inhibitory molecule
FAM86C1 family with sequence similarity 86, member C1
FLT4 fms-related tyrosine kinase 4
FNTB farnesyltransferase, CAAX box, beta
GALK1 galactokinase 1
GAN gigaxonin
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GJA1 gap junction protein, alpha 1, 43kDa
HAUS6 HAUS augmin-like complex, subunit 6
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIRA histone cell cycle regulator
HIST1H2BJ histone cluster 1, H2bj
HP1BP3 heterochromatin protein 1, binding protein 3
IL15RA interleukin 15 receptor, alpha
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KIAA0125 KIAA0125
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL26 kelch-like family member 26
LDHB lactate dehydrogenase B
LINS lines homolog (Drosophila)
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRRC49 leucine rich repeat containing 49
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYZ lysozyme
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP1S microtubule-associated protein 1S
MAP9 microtubule-associated protein 9
MAPK12 mitogen-activated protein kinase 12
MBTD1 mbt domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MED9 mediator complex subunit 9
MGC12488
MMP9 matrix metallopeptidase 9
NAV2 neuron navigator 2
NFE2L3 nuclear factor, erythroid 2-like 3
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NRGN neurogranin (protein kinase C substrate, RC3)
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PGM1 phosphoglucomutase 1
PRSS22 protease, serine, 22
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RAB3A RAB3A, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RANGRF RAN guanine nucleotide release factor
RASAL1 RAS protein activator like 1 (GAP1 like)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF31 ring finger protein 31
RNF38 ring finger protein 38
S100A4 S100 calcium binding protein A4
SDC3 syndecan 3
SGK1 serum/glucocorticoid regulated kinase 1
SGPP1 sphingosine-1-phosphate phosphatase 1
SH2B3 SH2B adaptor protein 3
SIK1 salt-inducible kinase 1
SKA1 spindle and kinetochore associated complex subunit 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC35F6 solute carrier family 35, member F6
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPINK4 serine peptidase inhibitor, Kazal type 4
SSBP3 single stranded DNA binding protein 3
STARD13 StAR-related lipid transfer (START) domain containing 13
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
TESC tescalcin
TET3 tet methylcytosine dioxygenase 3
TMPRSS3 transmembrane protease, serine 3
TPCN1 two pore segment channel 1
TPST2 tyrosylprotein sulfotransferase 2
WDR25 WD repeat domain 25
ZBTB25 zinc finger and BTB domain containing 25
ZBTB6 zinc finger and BTB domain containing 6
ZNF16 zinc finger protein 16
ZNF184 zinc finger protein 184
ZNF34 zinc finger protein 34
ZNF473 zinc finger protein 473