mifepristone-5827 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the mifepristone-5827 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C2 aldo-keto reductase family 1, member C2
ANGPTL4 angiopoietin-like 4
APOH apolipoprotein H (beta-2-glycoprotein I)
AQP3 aquaporin 3 (Gill blood group)
BEX4 brain expressed, X-linked 4
BGN biglycan
CA5BP1 carbonic anhydrase VB pseudogene 1
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCR1 chemokine (C-C motif) receptor 1
CDK6 cyclin-dependent kinase 6
CNGB3 cyclic nucleotide gated channel beta 3
COMT catechol-O-methyltransferase
DUSP2 dual specificity phosphatase 2
EML3 echinoderm microtubule associated protein like 3
EPHB2 EPH receptor B2
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FABP4 fatty acid binding protein 4, adipocyte
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGF5 fibroblast growth factor 5
FGFR1 fibroblast growth factor receptor 1
FLOT1 flotillin 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLRB glycine receptor, beta
GPR137 G protein-coupled receptor 137
GPSM3 G-protein signaling modulator 3
GRAMD4 GRAM domain containing 4
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HHAT hedgehog acyltransferase
HOXA11 homeobox A11
HPX hemopexin
IFNA14 interferon, alpha 14
IKZF4 IKAROS family zinc finger 4 (Eos)
IL1R2 interleukin 1 receptor, type II
IQCK IQ motif containing K
IRF1 interferon regulatory factor 1
JAM2 junctional adhesion molecule 2
KIAA0368 KIAA0368
KIF1A kinesin family member 1A
KIF5C kinesin family member 5C
LOC257152 uncharacterized LOC257152
LPIN1 lipin 1
LYPD3 LY6/PLAUR domain containing 3
MED25 mediator complex subunit 25
METTL7A methyltransferase like 7A
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MXD4 MAX dimerization protein 4
MYF5 myogenic factor 5
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYRF myelin regulatory factor
N4BP2L2 NEDD4 binding protein 2-like 2
NR2E3 nuclear receptor subfamily 2, group E, member 3
NRXN3 neurexin 3
OSBPL2 oxysterol binding protein-like 2
PDGFB platelet-derived growth factor beta polypeptide
PELO pelota homolog (Drosophila)
PF4 platelet factor 4
PHKG2 phosphorylase kinase, gamma 2 (testis)
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PLIN2 perilipin 2
PLK3 polo-like kinase 3
PLXNA2 plexin A2
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRAMEF11 PRAME family member 11
PRSS22 protease, serine, 22
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGES prostaglandin E synthase
PTK6 protein tyrosine kinase 6
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB26 RAB26, member RAS oncogene family
RGS12 regulator of G-protein signaling 12
RHOBTB3 Rho-related BTB domain containing 3
RTEL1 regulator of telomere elongation helicase 1
SAMD4A sterile alpha motif domain containing 4A
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC38A7 solute carrier family 38, member 7
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SOS1 son of sevenless homolog 1 (Drosophila)
SPRYD7 SPRY domain containing 7
SSH3 slingshot protein phosphatase 3
SULF1 sulfatase 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TIMP4 TIMP metallopeptidase inhibitor 4
TLE2 transducin-like enhancer of split 2
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM206 transmembrane protein 206
TMEM246 transmembrane protein 246
TMEM63A transmembrane protein 63A
TRIM14 tripartite motif containing 14
TRIM25 tripartite motif containing 25
TRO trophinin
TSFM Ts translation elongation factor, mitochondrial
VNN2 vanin 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB43 zinc finger and BTB domain containing 43
ZNF571 zinc finger protein 571
ZNF606 zinc finger protein 606
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALS2CL ALS2 C-terminal like
ANG angiogenin, ribonuclease, RNase A family, 5
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ASB8 ankyrin repeat and SOCS box containing 8
ASCC1 activating signal cointegrator 1 complex subunit 1
BDNF brain-derived neurotrophic factor
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF63 chromosome 11 open reading frame 63
C7ORF43 chromosome 7 open reading frame 43
CCDC88C coiled-coil domain containing 88C
CDH3 cadherin 3, type 1, P-cadherin (placental)
CEP70 centrosomal protein 70kDa
CHKB choline kinase beta
CNN2 calponin 2
COL5A2 collagen, type V, alpha 2
CORT cortistatin
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTGF connective tissue growth factor
CUL9 cullin 9
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL3 chemokine (C-X-C motif) ligand 3
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DCLRE1A DNA cross-link repair 1A
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DENND5A DENN/MADD domain containing 5A
DHRS3 dehydrogenase/reductase (SDR family) member 3
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EPPK1 epiplakin 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC3 exocyst complex component 3
GABPA GA binding protein transcription factor, alpha subunit 60kDa
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HELZ helicase with zinc finger
HIST1H2BF histone cluster 1, H2bf
HOOK2 hook microtubule-tethering protein 2
KIAA0232 KIAA0232
KIRREL kin of IRRE like (Drosophila)
LAMB2 laminin, beta 2 (laminin S)
LMBR1L limb development membrane protein 1-like
LYPD1 LY6/PLAUR domain containing 1
MAST3 microtubule associated serine/threonine kinase 3
MEIS1 Meis homeobox 1
MTG1 mitochondrial ribosome-associated GTPase 1
MUC3B mucin 3B, cell surface associated
MYL5 myosin, light chain 5, regulatory
NDE1 nudE neurodevelopment protein 1
NHLRC2 NHL repeat containing 2
NUP62CL nucleoporin 62kDa C-terminal like
OGFRL1 opioid growth factor receptor-like 1
OLFML2A olfactomedin-like 2A
OPLAH 5-oxoprolinase (ATP-hydrolysing)
PDZD2 PDZ domain containing 2
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCD1 phospholipase C, delta 1
PLK2 polo-like kinase 2
PNRC1 proline-rich nuclear receptor coactivator 1
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PRR15L proline rich 15-like
PTDSS2 phosphatidylserine synthase 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RGS19 regulator of G-protein signaling 19
RNF123 ring finger protein 123
RNF126P1 ring finger protein 126 pseudogene 1
SCEL sciellin
SHROOM2 shroom family member 2
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SPHK1 sphingosine kinase 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STARD13 StAR-related lipid transfer (START) domain containing 13
STEAP4 STEAP family member 4
STX5 syntaxin 5
TMCC2 transmembrane and coiled-coil domain family 2
TMEM177 transmembrane protein 177
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UBXN6 UBX domain protein 6
USP27X ubiquitin specific peptidase 27, X-linked
VASH2 vasohibin 2
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR46 WD repeat domain 46
ZBTB48 zinc finger and BTB domain containing 48
ZC3H3 zinc finger CCCH-type containing 3
ZDHHC24 zinc finger, DHHC-type containing 24
ZFHX4 zinc finger homeobox 4
ZNF273 zinc finger protein 273
ZNF280D zinc finger protein 280D
ZNF767P zinc finger family member 767, pseudogene
ZNF787 zinc finger protein 787
ZNF83 zinc finger protein 83