mild pre-eclampsia Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A pre-eclampsia characterized by the presence of hypertension without evidence of end-organ damage, in a woman who was normotensive before 20 weeks' gestation. (Human Disease Ontology, DOID_10590)
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Genes

76 genes co-occuring with the disease mild pre-eclampsia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
LNPEP leucyl/cystinyl aminopeptidase 0.899924
FLT1 fms-related tyrosine kinase 1 0.852811
LEP leptin 0.825768
PGF placental growth factor 0.813462
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 0.722077
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.714811
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 0.703134
KISS1 KiSS-1 metastasis-suppressor 0.686291
THBD thrombomodulin 0.663975
GPX5 glutathione peroxidase 5 0.633169
GPX4 glutathione peroxidase 4 0.630027
GPX1 glutathione peroxidase 1 0.613965
ALB albumin 0.589779
LGALS1 lectin, galactoside-binding, soluble, 1 0.586665
LGALS13 lectin, galactoside-binding, soluble, 13 0.57655
LPAR2 lysophosphatidic acid receptor 2 0.563723
CHIT1 chitinase 1 (chitotriosidase) 0.559062
WRAP73 WD repeat containing, antisense to TP73 0.542767
KLRC2 killer cell lectin-like receptor subfamily C, member 2 0.53657
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.52536
IGFBP1 insulin-like growth factor binding protein 1 0.521117
NOS3 nitric oxide synthase 3 (endothelial cell) 0.516494
RERE arginine-glutamic acid dipeptide (RE) repeats 0.51611
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.514186
VCAM1 vascular cell adhesion molecule 1 0.474877
TPRG1L tumor protein p63 regulated 1-like 0.459373
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.455978
PAPPA pregnancy-associated plasma protein A, pappalysin 1 0.455601
IL1RL1 interleukin 1 receptor-like 1 0.445052
CSH2 chorionic somatomammotropin hormone 2 0.435651
CDK11A cyclin-dependent kinase 11A 0.433772
CALCRL calcitonin receptor-like 0.40904
NAMPT nicotinamide phosphoribosyltransferase 0.396353
CRP C-reactive protein, pentraxin-related 0.394863
HLA-E major histocompatibility complex, class I, E 0.390769
NPPA natriuretic peptide A 0.385565
ADAM12 ADAM metallopeptidase domain 12 0.372217
AGTR1 angiotensin II receptor, type 1 0.358183
IL16 interleukin 16 0.355604
LCN2 lipocalin 2 0.349349
IGFBP3 insulin-like growth factor binding protein 3 0.344941
INS insulin 0.337975
IL6 interleukin 6 0.318272
KLRC1 killer cell lectin-like receptor subfamily C, member 1 0.305226
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.304503
MIR210 microRNA 210 0.294413
TNF tumor necrosis factor 0.293694
DLK1 delta-like 1 homolog (Drosophila) 0.292616
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.290462
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.276514
IL31RA interleukin 31 receptor A 0.271886
LIPC lipase, hepatic 0.266203
IGF1 insulin-like growth factor 1 (somatomedin C) 0.264785
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.261599
NTN1 netrin 1 0.25983
IFNGR1 interferon gamma receptor 1 0.259477
F5 coagulation factor V (proaccelerin, labile factor) 0.257005
SOD2 superoxide dismutase 2, mitochondrial 0.255946
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.245046
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.244696
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.244345
GPX3 glutathione peroxidase 3 0.243295
FN1 fibronectin 1 0.225229
CP ceruloplasmin (ferroxidase) 0.223509
UTS2 urotensin 2 0.212945
PF4 platelet factor 4 0.201962
CDA cytidine deaminase 0.199356
FABP4 fatty acid binding protein 4, adipocyte 0.197742
AQP1 aquaporin 1 (Colton blood group) 0.192657
F2 coagulation factor II (thrombin) 0.191097
PLA2G1B phospholipase A2, group IB (pancreas) 0.186811
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.183541
RBP4 retinol binding protein 4, plasma 0.177851
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.171286
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 0.164786
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.161716