milrinone-3552 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the milrinone-3552 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACPP acid phosphatase, prostate
ADGRE1 adhesion G protein-coupled receptor E1
AKAP8L A kinase (PRKA) anchor protein 8-like
ALOX15B arachidonate 15-lipoxygenase, type B
ALOX5 arachidonate 5-lipoxygenase
APC adenomatous polyposis coli
ARID1A AT rich interactive domain 1A (SWI-like)
ASIC3 acid sensing (proton gated) ion channel 3
ATXN8OS ATXN8 opposite strand (non-protein coding)
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BIN1 bridging integrator 1
CA4 carbonic anhydrase IV
CAMK1 calcium/calmodulin-dependent protein kinase I
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCR7 chemokine (C-C motif) receptor 7
CD53 CD53 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CFAP69 cilia and flagella associated protein 69
CHN2 chimerin 2
CLIC2 chloride intracellular channel 2
CLUL1 clusterin-like 1 (retinal)
CNTNAP2 contactin associated protein-like 2
COL1A1 collagen, type I, alpha 1
COL5A2 collagen, type V, alpha 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CSF1R colony stimulating factor 1 receptor
ERAP1 endoplasmic reticulum aminopeptidase 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ERO1LB ERO1-like beta (S. cerevisiae)
EVA1B eva-1 homolog B (C. elegans)
FAM110B family with sequence similarity 110, member B
FAM46C family with sequence similarity 46, member C
FLNC filamin C, gamma
FOLH1B folate hydrolase 1B
FRMD4A FERM domain containing 4A
GREB1 growth regulation by estrogen in breast cancer 1
HAUS5 HAUS augmin-like complex, subunit 5
HDAC7 histone deacetylase 7
HFE hemochromatosis
HOXB6 homeobox B6
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IDI2-AS1 IDI2 antisense RNA 1
IL16 interleukin 16
IPW imprinted in Prader-Willi syndrome (non-protein coding)
JAM3 junctional adhesion molecule 3
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KIF25-AS1 KIF25 antisense RNA 1
KLK13 kallikrein-related peptidase 13
KRIT1 KRIT1, ankyrin repeat containing
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LMTK1 lemur tail kinase 1
LTBP4 latent transforming growth factor beta binding protein 4
MAN1C1 mannosidase, alpha, class 1C, member 1
MEF2C myocyte enhancer factor 2C
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MMP25 matrix metallopeptidase 25
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYO7A myosin VIIA
NEU2 sialidase 2 (cytosolic sialidase)
NEURL1 neuralized E3 ubiquitin protein ligase 1
NOD1 nucleotide-binding oligomerization domain containing 1
NOL10 nucleolar protein 10
NR2E3 nuclear receptor subfamily 2, group E, member 3
OASL 2'-5'-oligoadenylate synthetase-like
OCM2 oncomodulin 2
PC pyruvate carboxylase
PCDH7 protocadherin 7
PDZD2 PDZ domain containing 2
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
POFUT1 protein O-fucosyltransferase 1
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSG9 pregnancy specific beta-1-glycoprotein 9
PTK2B protein tyrosine kinase 2 beta
PTN pleiotrophin
REC8 REC8 meiotic recombination protein
RIMS2 regulating synaptic membrane exocytosis 2
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RTCA RNA 3'-terminal phosphate cyclase
RUNX1 runt-related transcription factor 1
S100A8 S100 calcium binding protein A8
SCN10A sodium channel, voltage gated, type X alpha subunit
SDS serine dehydratase
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPHK2 sphingosine kinase 2
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
STK24 serine/threonine kinase 24
TMEM144 transmembrane protein 144
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TPP1 tripeptidyl peptidase I
TSC22D4 TSC22 domain family, member 4
UBXN1 UBX domain protein 1
USP46 ubiquitin specific peptidase 46
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VPS9D1 VPS9 domain containing 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ALDOC aldolase C, fructose-bisphosphate
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APOLD1 apolipoprotein L domain containing 1
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATAD3A ATPase family, AAA domain containing 3A
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BBS10 Bardet-Biedl syndrome 10
BRPF1 bromodomain and PHD finger containing, 1
BTF3P12 basic transcription factor 3 pseudogene 12
CCDC68 coiled-coil domain containing 68
CD83 CD83 molecule
CDK3 cyclin-dependent kinase 3
CENPO centromere protein O
CFAP45 cilia and flagella associated protein 45
CGA glycoprotein hormones, alpha polypeptide
CHML choroideremia-like (Rab escort protein 2)
CIR1 corepressor interacting with RBPJ, 1
CLDND1 claudin domain containing 1
COG4 component of oligomeric golgi complex 4
CPTP ceramide-1-phosphate transfer protein
CRYBB2P1 crystallin, beta B2 pseudogene 1
CXADR coxsackie virus and adenovirus receptor
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEAF1 DEAF1 transcription factor
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EMD emerin
ENO2 enolase 2 (gamma, neuronal)
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FAAH fatty acid amide hydrolase
FAM127B family with sequence similarity 127, member B
FAM184A family with sequence similarity 184, member A
FKBP5 FK506 binding protein 5
FLCN folliculin
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GTF2I general transcription factor IIi
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIST1H4F histone cluster 1, H4f
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HPS6 Hermansky-Pudlak syndrome 6
IFT140 intraflagellar transport 140
ITPKB inositol-trisphosphate 3-kinase B
KDM5C lysine (K)-specific demethylase 5C
KLF2 Kruppel-like factor 2
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LINS lines homolog (Drosophila)
LRP2 low density lipoprotein receptor-related protein 2
MED15 mediator complex subunit 15
MED24 mediator complex subunit 24
MEFV Mediterranean fever
METTL16 methyltransferase like 16
MITF microphthalmia-associated transcription factor
MRPS18C mitochondrial ribosomal protein S18C
MTERF4 mitochondrial transcription termination factor 4
MTRF1 mitochondrial translational release factor 1
MYO1F myosin IF
NPFFR1 neuropeptide FF receptor 1
PADI1 peptidyl arginine deiminase, type I
PCDHB3 protocadherin beta 3
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G3 phospholipase A2, group III
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PRRC1 proline-rich coiled-coil 1
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTDSS2 phosphatidylserine synthase 2
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RECQL4 RecQ protein-like 4
RLN1 relaxin 1
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
RUNDC3B RUN domain containing 3B
S100A4 S100 calcium binding protein A4
SCD5 stearoyl-CoA desaturase 5
SHARPIN SHANK-associated RH domain interactor
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
STBD1 starch binding domain 1
STIM1 stromal interaction molecule 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SULT4A1 sulfotransferase family 4A, member 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TBC1D19 TBC1 domain family, member 19
TKFC triokinase/FMN cyclase
TLR5 toll-like receptor 5
TMPRSS3 transmembrane protease, serine 3
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRAPPC11 trafficking protein particle complex 11
WDR76 WD repeat domain 76
ZNF227 zinc finger protein 227
ZNF623 zinc finger protein 623
ZNF747 zinc finger protein 747
ZNF787 zinc finger protein 787