milrinone-5856 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the milrinone-5856 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
AKAP8L A kinase (PRKA) anchor protein 8-like
ANXA10 annexin A10
ARHGAP44 Rho GTPase activating protein 44
ARRB2 arrestin, beta 2
ASMTL acetylserotonin O-methyltransferase-like
BMP8B bone morphogenetic protein 8b
BRD4 bromodomain containing 4
CA5B carbonic anhydrase VB, mitochondrial
CACTIN cactin, spliceosome C complex subunit
CCDC170 coiled-coil domain containing 170
CD1A CD1a molecule
CD200 CD200 molecule
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CNOT4 CCR4-NOT transcription complex, subunit 4
COBL cordon-bleu WH2 repeat protein
COL2A1 collagen, type II, alpha 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CXCL13 chemokine (C-X-C motif) ligand 13
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DPF3 D4, zinc and double PHD fingers, family 3
DSTYK dual serine/threonine and tyrosine protein kinase
DZIP3 DAZ interacting zinc finger protein 3
EFNB3 ephrin-B3
EGFR epidermal growth factor receptor
ERAP1 endoplasmic reticulum aminopeptidase 1
ESR1 estrogen receptor 1
FBLN1 fibulin 1
FBXO21 F-box protein 21
FMO5 flavin containing monooxygenase 5
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GHRHR growth hormone releasing hormone receptor
GLUL glutamate-ammonia ligase
GRIA3 glutamate receptor, ionotropic, AMPA 3
GSTTP1 glutathione S-transferase theta pseudogene 1
HIC2 hypermethylated in cancer 2
HMGN5 high mobility group nucleosome binding domain 5
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
IGFBP5 insulin-like growth factor binding protein 5
INADL InaD-like (Drosophila)
ISG20 interferon stimulated exonuclease gene 20kDa
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LIMK2 LIM domain kinase 2
LRP1 low density lipoprotein receptor-related protein 1
LRP6 low density lipoprotein receptor-related protein 6
LTBP4 latent transforming growth factor beta binding protein 4
MAPT microtubule-associated protein tau
MEFV Mediterranean fever
MTCP1 mature T-cell proliferation 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NF1 neurofibromin 1
NRXN3 neurexin 3
NT5M 5',3'-nucleotidase, mitochondrial
OBSL1 obscurin-like 1
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PADI2 peptidyl arginine deiminase, type II
PARM1 prostate androgen-regulated mucin-like protein 1
PCSK2 proprotein convertase subtilisin/kexin type 2
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLCH1 phospholipase C, eta 1
POU3F2 POU class 3 homeobox 2
PRKCI protein kinase C, iota
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PRSS8 protease, serine, 8
QKI QKI, KH domain containing, RNA binding
R3HDM1 R3H domain containing 1
RAD50 RAD50 homolog (S. cerevisiae)
RARA retinoic acid receptor, alpha
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RNGTT RNA guanylyltransferase and 5'-phosphatase
RUNX1 runt-related transcription factor 1
SAA4 serum amyloid A4, constitutive
SCN10A sodium channel, voltage gated, type X alpha subunit
SLA Src-like-adaptor
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SOCS7 suppressor of cytokine signaling 7
SOSTDC1 sclerostin domain containing 1
SOX4 SRY (sex determining region Y)-box 4
SPINK5 serine peptidase inhibitor, Kazal type 5
STK17A serine/threonine kinase 17a
TACC1 transforming, acidic coiled-coil containing protein 1
TMEM180 transmembrane protein 180
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TOX thymocyte selection-associated high mobility group box
TXNRD2 thioredoxin reductase 2
UNC5C unc-5 homolog C (C. elegans)
UNC93B1 unc-93 homolog B1 (C. elegans)
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
ZER1 zyg-11 related, cell cycle regulator
ZNF358 zinc finger protein 358
ZNF362 zinc finger protein 362
ZNF606 zinc finger protein 606

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANAPC2 anaphase promoting complex subunit 2
AP3M2 adaptor-related protein complex 3, mu 2 subunit
APH1B APH1B gamma secretase subunit
APOL6 apolipoprotein L, 6
ARAF A-Raf proto-oncogene, serine/threonine kinase
ATP10D ATPase, class V, type 10D
BAK1 BCL2-antagonist/killer 1
BDH1 3-hydroxybutyrate dehydrogenase, type 1
C16ORF59 chromosome 16 open reading frame 59
C19ORF40 chromosome 19 open reading frame 40
C5 complement component 5
CCNT1 cyclin T1
CDK3 cyclin-dependent kinase 3
CEP70 centrosomal protein 70kDa
CLCN2 chloride channel, voltage-sensitive 2
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CRABP2 cellular retinoic acid binding protein 2
CRELD1 cysteine-rich with EGF-like domains 1
DCAF17 DDB1 and CUL4 associated factor 17
DDB2 damage-specific DNA binding protein 2, 48kDa
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DLL3 delta-like 3 (Drosophila)
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ERMAP erythroblast membrane-associated protein (Scianna blood group)
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GAMT guanidinoacetate N-methyltransferase
GLCE glucuronic acid epimerase
GMIP GEM interacting protein
HAMP hepcidin antimicrobial peptide
HIST1H3G histone cluster 1, H3g
HIST2H2AA3 histone cluster 2, H2aa3
HIST3H2A histone cluster 3, H2a
IFNA14 interferon, alpha 14
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRF2 interferon regulatory factor 2
KCTD15 potassium channel tetramerization domain containing 15
KDM5C lysine (K)-specific demethylase 5C
KIF13B kinesin family member 13B
LOC730101 uncharacterized LOC730101
LRRC15 leucine rich repeat containing 15
MAP9 microtubule-associated protein 9
MAST3 microtubule associated serine/threonine kinase 3
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MOXD1 monooxygenase, DBH-like 1
NOTCH1 notch 1
NPM3 nucleophosmin/nucleoplasmin 3
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NXPE3 neurexophilin and PC-esterase domain family, member 3
ODF2 outer dense fiber of sperm tails 2
ORAI3 ORAI calcium release-activated calcium modulator 3
PARP16 poly (ADP-ribose) polymerase family, member 16
PHC1 polyhomeotic homolog 1 (Drosophila)
PHKG2 phosphorylase kinase, gamma 2 (testis)
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIEZO1 piezo-type mechanosensitive ion channel component 1
POLM polymerase (DNA directed), mu
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRSS16 protease, serine, 16 (thymus)
RAB3A RAB3A, member RAS oncogene family
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RNF122 ring finger protein 122
RNF170 ring finger protein 170
RPL10L ribosomal protein L10-like
RUFY2 RUN and FYVE domain containing 2
SCN1B sodium channel, voltage gated, type I beta subunit
SCPEP1 serine carboxypeptidase 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SIRT2 sirtuin 2
SLC22A18 solute carrier family 22, member 18
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SNIP1 Smad nuclear interacting protein 1
SNTA1 syntrophin, alpha 1
SOD3 superoxide dismutase 3, extracellular
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STEAP3 STEAP family member 3, metalloreductase
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAGLN3 transgelin 3
TBL3 transducin (beta)-like 3
TMEM156 transmembrane protein 156
TMEM209 transmembrane protein 209
TMOD3 tropomodulin 3 (ubiquitous)
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRDMT1 tRNA aspartic acid methyltransferase 1
TTBK2 tau tubulin kinase 2
TUBGCP5 tubulin, gamma complex associated protein 5
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TWSG1 twisted gastrulation BMP signaling modulator 1
URM1 ubiquitin related modifier 1
ZBED1 zinc finger, BED-type containing 1
ZBTB48 zinc finger and BTB domain containing 48
ZHX2 zinc fingers and homeoboxes 2
ZNF134 zinc finger protein 134
ZNF408 zinc finger protein 408
ZNF552 zinc finger protein 552