milrinone-7210 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the milrinone-7210 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ADAM3A ADAM metallopeptidase domain 3A (pseudogene)
ALDOB aldolase B, fructose-bisphosphate
AQR aquarius intron-binding spliceosomal factor
ARNT aryl hydrocarbon receptor nuclear translocator
ARRB1 arrestin, beta 1
ART1 ADP-ribosyltransferase 1
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BMP8A bone morphogenetic protein 8a
C16ORF71 chromosome 16 open reading frame 71
CADM3 cell adhesion molecule 3
CALB1 calbindin 1, 28kDa
CALB2 calbindin 2
CASP5 caspase 5, apoptosis-related cysteine peptidase
CD82 CD82 molecule
CD8A CD8a molecule
CDRT1 CMT1A duplicated region transcript 1
CLPS colipase, pancreatic
COL1A1 collagen, type I, alpha 1
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DLC1 DLC1 Rho GTPase activating protein
DOCK6 dedicator of cytokinesis 6
DSCR4 Down syndrome critical region 4
DTX2 deltex 2, E3 ubiquitin ligase
DUSP9 dual specificity phosphatase 9
ELOVL5 ELOVL fatty acid elongase 5
ETV5 ets variant 5
F5 coagulation factor V (proaccelerin, labile factor)
FBLN1 fibulin 1
FBXL2 F-box and leucine-rich repeat protein 2
FGFR1OP FGFR1 oncogene partner
FHL1 four and a half LIM domains 1
FLOT1 flotillin 1
FLT4 fms-related tyrosine kinase 4
GALC galactosylceramidase
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GPC1 glypican 1
GPR3 G protein-coupled receptor 3
HCFC1 host cell factor C1
HDLBP high density lipoprotein binding protein
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXB6 homeobox B6
HP haptoglobin
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IGFBP5 insulin-like growth factor binding protein 5
IGHMBP2 immunoglobulin mu binding protein 2
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
ITM2C integral membrane protein 2C
KLHL22 kelch-like family member 22
KLHL29 kelch-like family member 29
LEFTY1 left-right determination factor 1
LIN7A lin-7 homolog A (C. elegans)
LTC4S leukotriene C4 synthase
MAP2K7 mitogen-activated protein kinase kinase 7
MARK4 MAP/microtubule affinity-regulating kinase 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
METTL7A methyltransferase like 7A
MIIP migration and invasion inhibitory protein
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NIPAL2 NIPA-like domain containing 2
NOTCH4 notch 4
NR2E3 nuclear receptor subfamily 2, group E, member 3
OTUD4 OTU deubiquitinase 4
PASK PAS domain containing serine/threonine kinase
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PSD4 pleckstrin and Sec7 domain containing 4
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRA protein tyrosine phosphatase, receptor type, A
RAD52 RAD52 homolog (S. cerevisiae)
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RCAN3 RCAN family member 3
RIMBP2 RIMS binding protein 2
RLN1 relaxin 1
S100A8 S100 calcium binding protein A8
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SH3BP2 SH3-domain binding protein 2
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIK2 salt-inducible kinase 2
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SMR3A submaxillary gland androgen regulated protein 3A
SPRY2 sprouty homolog 2 (Drosophila)
STXBP6 syntaxin binding protein 6 (amisyn)
TMEM212 transmembrane protein 212
TMOD1 tropomodulin 1
TUBA3C tubulin, alpha 3c
UPK2 uroplakin 2
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF286A zinc finger protein 286A
ZNF862 zinc finger protein 862
ZSCAN12 zinc finger and SCAN domain containing 12
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
ADCY6 adenylate cyclase 6
ADGRE5 adhesion G protein-coupled receptor E5
ANKRD36 ankyrin repeat domain 36
AP3M2 adaptor-related protein complex 3, mu 2 subunit
ARRB2 arrestin, beta 2
ASPHD1 aspartate beta-hydroxylase domain containing 1
AXIN1 axin 1
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BCL9 B-cell CLL/lymphoma 9
C1ORF159 chromosome 1 open reading frame 159
C7ORF43 chromosome 7 open reading frame 43
CASD1 CAS1 domain containing 1
CCNT1 cyclin T1
CISH cytokine inducible SH2-containing protein
CLDN15 claudin 15
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DCAF17 DDB1 and CUL4 associated factor 17
DGKD diacylglycerol kinase, delta 130kDa
DNM1 dynamin 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ELOVL4 ELOVL fatty acid elongase 4
EXOC2 exocyst complex component 2
FAAH fatty acid amide hydrolase
FAIM Fas apoptotic inhibitory molecule
FAM63A family with sequence similarity 63, member A
FBXL6 F-box and leucine-rich repeat protein 6
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGGY FGGY carbohydrate kinase domain containing
FOXA1 forkhead box A1
GAREM GRB2 associated, regulator of MAPK1
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GLI3 GLI family zinc finger 3
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIST1H2BO histone cluster 1, H2bo
IL4R interleukin 4 receptor
KAT2B K(lysine) acetyltransferase 2B
KCNK15 potassium channel, two pore domain subfamily K, member 15
KDM5C lysine (K)-specific demethylase 5C
KIAA0125 KIAA0125
KLHL2 kelch-like family member 2
L2HGDH L-2-hydroxyglutarate dehydrogenase
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LMNB1 lamin B1
LOXL1 lysyl oxidase-like 1
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LZTFL1 leucine zipper transcription factor-like 1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBTD1 mbt domain containing 1
MNX1 motor neuron and pancreas homeobox 1
MPI mannose phosphate isomerase
MXD3 MAX dimerization protein 3
MYO1E myosin IE
NCAM2 neural cell adhesion molecule 2
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
OSMR oncostatin M receptor
PCSK7 proprotein convertase subtilisin/kexin type 7
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PEX26 peroxisomal biogenesis factor 26
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
POLI polymerase (DNA directed) iota
PRSS22 protease, serine, 22
PRSS8 protease, serine, 8
PTTG3P pituitary tumor-transforming 3, pseudogene
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBM23 RNA binding motif protein 23
SCG2 secretogranin II
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC41A3 solute carrier family 41, member 3
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SOX12 SRY (sex determining region Y)-box 12
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SSFA2 sperm specific antigen 2
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SYNGR3 synaptogyrin 3
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TMEM104 transmembrane protein 104
TMEM254 transmembrane protein 254
TMEM38B transmembrane protein 38B
TRIM5 tripartite motif containing 5
TRIP10 thyroid hormone receptor interactor 10
TUBGCP5 tubulin, gamma complex associated protein 5
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TYK2 tyrosine kinase 2
USP18 ubiquitin specific peptidase 18
WASF1 WAS protein family, member 1
WDR62 WD repeat domain 62
ZFP69B ZFP69 zinc finger protein B
ZNF430 zinc finger protein 430
ZNF492 zinc finger protein 492