mimosine-2638 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the mimosine-2638 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP11 A kinase (PRKA) anchor protein 11
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ANGPTL2 angiopoietin-like 2
ANKRD6 ankyrin repeat domain 6
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
ATP9B ATPase, class II, type 9B
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BAZ1B bromodomain adjacent to zinc finger domain, 1B
C17ORF59 chromosome 17 open reading frame 59
C8ORF60 chromosome 8 open reading frame 60
C9ORF156 chromosome 9 open reading frame 156
CA4 carbonic anhydrase IV
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CD79A CD79a molecule, immunoglobulin-associated alpha
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEP41 centrosomal protein 41kDa
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
DLX2 distal-less homeobox 2
DMC1 DNA meiotic recombinase 1
DUSP2 dual specificity phosphatase 2
EFR3B EFR3 homolog B (S. cerevisiae)
ELL elongation factor RNA polymerase II
ELN elastin
ELOVL5 ELOVL fatty acid elongase 5
FCAR Fc fragment of IgA receptor
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FGF6 fibroblast growth factor 6
FOXG1 forkhead box G1
FRAS1 Fraser extracellular matrix complex subunit 1
FSCN1 fascin actin-bundling protein 1
GAP43 growth associated protein 43
GPR135 G protein-coupled receptor 135
H2AFY H2A histone family, member Y
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
IL6R interleukin 6 receptor
IQSEC2 IQ motif and Sec7 domain 2
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KLK1 kallikrein 1
LARP7 La ribonucleoprotein domain family, member 7
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LRRC75B leucine rich repeat containing 75B
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MANBA mannosidase, beta A, lysosomal
MAP2K7 mitogen-activated protein kinase kinase 7
MPPE1 metallophosphoesterase 1
MTA1 metastasis associated 1
NCR2 natural cytotoxicity triggering receptor 2
NELL2 NEL-like 2 (chicken)
NPY2R neuropeptide Y receptor Y2
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NR2F1 nuclear receptor subfamily 2, group F, member 1
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
OGFR opioid growth factor receptor
PARP16 poly (ADP-ribose) polymerase family, member 16
PARVB parvin, beta
PCDHGB5 protocadherin gamma subfamily B, 5
PDAP1 PDGFA associated protein 1
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PHTF2 putative homeodomain transcription factor 2
PLCL2 phospholipase C-like 2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PTPRU protein tyrosine phosphatase, receptor type, U
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS12 regulator of G-protein signaling 12
RPL10 ribosomal protein L10
RPLP2 ribosomal protein, large, P2
SAG S-antigen; retina and pineal gland (arrestin)
SAV1 salvador family WW domain containing protein 1
SCAI suppressor of cancer cell invasion
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SFTPC surfactant protein C
SH3BP2 SH3-domain binding protein 2
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPX spexin hormone
SRD5A3 steroid 5 alpha-reductase 3
SYMPK symplekin
SYNJ2 synaptojanin 2
SZRD1 SUZ RNA binding domain containing 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAS2R10 taste receptor, type 2, member 10
TBX6 T-box 6
TENM1 teneurin transmembrane protein 1
TMEM53 transmembrane protein 53
TTLL4 tubulin tyrosine ligase-like family member 4
UTRN utrophin
VLDLR very low density lipoprotein receptor
WDR59 WD repeat domain 59
WIPF1 WAS/WASL interacting protein family, member 1
XYLB xylulokinase homolog (H. influenzae)
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ARRB1 arrestin, beta 1
ATF3 activating transcription factor 3
BIRC7 baculoviral IAP repeat containing 7
BMP4 bone morphogenetic protein 4
C14ORF93 chromosome 14 open reading frame 93
CCP110 centriolar coiled coil protein 110kDa
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD302 CD302 molecule
CDK3 cyclin-dependent kinase 3
CENPJ centromere protein J
CEP97 centrosomal protein 97kDa
CLCN5 chloride channel, voltage-sensitive 5
CSTA cystatin A (stefin A)
CTDNEP1 CTD nuclear envelope phosphatase 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DGKE diacylglycerol kinase, epsilon 64kDa
DOC2A double C2-like domains, alpha
DYSF dysferlin
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FBXL6 F-box and leucine-rich repeat protein 6
FER fer (fps/fes related) tyrosine kinase
FKBP10 FK506 binding protein 10, 65 kDa
FMOD fibromodulin
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FPGS folylpolyglutamate synthase
GALT galactose-1-phosphate uridylyltransferase
GEMIN8 gem (nuclear organelle) associated protein 8
GID4 GID complex subunit 4
HIST1H3B histone cluster 1, H3b
HIST1H4D histone cluster 1, H4d
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXC10 homeobox C10
IL17RA interleukin 17 receptor A
IPO13 importin 13
IPO8 importin 8
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KLHL25 kelch-like family member 25
KLHL26 kelch-like family member 26
LAMB1 laminin, beta 1
LIG4 ligase IV, DNA, ATP-dependent
LINC00115 long intergenic non-protein coding RNA 115
LINS lines homolog (Drosophila)
LRP3 low density lipoprotein receptor-related protein 3
LRRC42 leucine rich repeat containing 42
LRRC49 leucine rich repeat containing 49
LY6G6C lymphocyte antigen 6 complex, locus G6C
MATK megakaryocyte-associated tyrosine kinase
MBOAT2 membrane bound O-acyltransferase domain containing 2
MFAP2 microfibrillar-associated protein 2
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
NBEAL2 neurobeachin-like 2
NEO1 neogenin 1
NPM3 nucleophosmin/nucleoplasmin 3
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
ODF2 outer dense fiber of sperm tails 2
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PADI1 peptidyl arginine deiminase, type I
PHEX phosphate regulating endopeptidase homolog, X-linked
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POLL polymerase (DNA directed), lambda
PTPRE protein tyrosine phosphatase, receptor type, E
PYCR1 pyrroline-5-carboxylate reductase 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RNF146 ring finger protein 146
ROM1 retinal outer segment membrane protein 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC12A8 solute carrier family 12, member 8
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SOX12 SRY (sex determining region Y)-box 12
SOX3 SRY (sex determining region Y)-box 3
SPINK5 serine peptidase inhibitor, Kazal type 5
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STK16 serine/threonine kinase 16
SYT17 synaptotagmin XVII
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMC7 transmembrane channel-like 7
TMEM184C transmembrane protein 184C
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TPCN1 two pore segment channel 1
TRIM25 tripartite motif containing 25
USP36 ubiquitin specific peptidase 36
VAV1 vav 1 guanine nucleotide exchange factor
VGF VGF nerve growth factor inducible
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF254 zinc finger protein 254
ZNF280D zinc finger protein 280D
ZNF324 zinc finger protein 324
ZNF34 zinc finger protein 34
ZNF446 zinc finger protein 446