minaprine-1468 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the minaprine-1468 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASIC3 acid sensing (proton gated) ion channel 3
ATP11A ATPase, class VI, type 11A
C2ORF72 chromosome 2 open reading frame 72
CAMK1D calcium/calmodulin-dependent protein kinase ID
CCPG1 cell cycle progression 1
CFLAR CASP8 and FADD-like apoptosis regulator
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
CLDN17 claudin 17
CLU clusterin
COL1A1 collagen, type I, alpha 1
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DICER1 dicer 1, ribonuclease type III
DMWD dystrophia myotonica, WD repeat containing
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EDNRA endothelin receptor type A
EFR3B EFR3 homolog B (S. cerevisiae)
ELOVL5 ELOVL fatty acid elongase 5
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERAP1 endoplasmic reticulum aminopeptidase 1
ESR1 estrogen receptor 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM169A family with sequence similarity 169, member A
FBXO11 F-box protein 11
FGL2 fibrinogen-like 2
FLJ11292
GOSR2 golgi SNAP receptor complex member 2
GPRC5D G protein-coupled receptor, class C, group 5, member D
HDAC11 histone deacetylase 11
HOXC10 homeobox C10
IDS iduronate 2-sulfatase
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIF25-AS1 KIF25 antisense RNA 1
KMT2A lysine (K)-specific methyltransferase 2A
LAMP1 lysosomal-associated membrane protein 1
LIMCH1 LIM and calponin homology domains 1
LMAN1 lectin, mannose-binding, 1
LOC399491
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAPK8 mitogen-activated protein kinase 8
MGC12488
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MRPL41 mitochondrial ribosomal protein L41
NCAPH2 non-SMC condensin II complex, subunit H2
NF2 neurofibromin 2 (merlin)
NOP16 NOP16 nucleolar protein
NOTCH4 notch 4
NPTXR neuronal pentraxin receptor
NTF3 neurotrophin 3
OSGIN2 oxidative stress induced growth inhibitor family member 2
PADI1 peptidyl arginine deiminase, type I
PARP16 poly (ADP-ribose) polymerase family, member 16
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
POU2F2 POU class 2 homeobox 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PSG9 pregnancy specific beta-1-glycoprotein 9
RAB6A RAB6A, member RAS oncogene family
RASAL2 RAS protein activator like 2
RBP4 retinol binding protein 4, plasma
RPL10L ribosomal protein L10-like
RPS14 ribosomal protein S14
RPS4Y1 ribosomal protein S4, Y-linked 1
RTEL1 regulator of telomere elongation helicase 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SCAND2P SCAN domain containing 2 pseudogene
SCAPER S-phase cyclin A-associated protein in the ER
SIGLEC6 sialic acid binding Ig-like lectin 6
SIK3 SIK family kinase 3
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPRR2B small proline-rich protein 2B
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SYK spleen tyrosine kinase
TAT tyrosine aminotransferase
TGM2 transglutaminase 2
TLR4 toll-like receptor 4
TMEM209 transmembrane protein 209
TMOD1 tropomodulin 1
TRIM21 tripartite motif containing 21
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TTC28 tetratricopeptide repeat domain 28
TWF2 twinfilin actin binding protein 2
WIPF1 WAS/WASL interacting protein family, member 1
XDH xanthine dehydrogenase
ZNF134 zinc finger protein 134

decreased expression

Symbol Name
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ADTRP androgen-dependent TFPI-regulating protein
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARMC6 armadillo repeat containing 6
ARRB1 arrestin, beta 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAD5 ATPase family, AAA domain containing 5
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BMP4 bone morphogenetic protein 4
C11ORF30 chromosome 11 open reading frame 30
C1ORF106 chromosome 1 open reading frame 106
C21ORF91 chromosome 21 open reading frame 91
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CENPT centromere protein T
CIC capicua transcriptional repressor
CLCN5 chloride channel, voltage-sensitive 5
CLSPN claspin
CST6 cystatin E/M
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
EFNA3 ephrin-A3
FBXO22 F-box protein 22
FGD1 FYVE, RhoGEF and PH domain containing 1
FOXN2 forkhead box N2
FRS2 fibroblast growth factor receptor substrate 2
FURIN furin (paired basic amino acid cleaving enzyme)
GAMT guanidinoacetate N-methyltransferase
GCHFR GTP cyclohydrolase I feedback regulator
GNG4 guanine nucleotide binding protein (G protein), gamma 4
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BC histone cluster 1, H2bc
IGFBP6 insulin-like growth factor binding protein 6
IL22 interleukin 22
IRF6 interferon regulatory factor 6
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITPKB inositol-trisphosphate 3-kinase B
KIZ kizuna centrosomal protein
KLC2 kinesin light chain 2
KREMEN2 kringle containing transmembrane protein 2
LAMA3 laminin, alpha 3
LIG4 ligase IV, DNA, ATP-dependent
LTBP2 latent transforming growth factor beta binding protein 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MED9 mediator complex subunit 9
MITF microphthalmia-associated transcription factor
MTHFSD methenyltetrahydrofolate synthetase domain containing
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PARP12 poly (ADP-ribose) polymerase family, member 12
PCSK7 proprotein convertase subtilisin/kexin type 7
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLA2G10 phospholipase A2, group X
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRR4 proline rich 4 (lacrimal)
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
REPS2 RALBP1 associated Eps domain containing 2
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RIN2 Ras and Rab interactor 2
RNF121 ring finger protein 121
RNF126P1 ring finger protein 126 pseudogene 1
RNF43 ring finger protein 43
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLMO1 slowmo homolog 1 (Drosophila)
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SND1-IT1 SND1 intronic transcript 1
SNHG3 small nucleolar RNA host gene 3
SP1 Sp1 transcription factor
SPRYD7 SPRY domain containing 7
STARD3 StAR-related lipid transfer (START) domain containing 3
STX5 syntaxin 5
TBX19 T-box 19
TDRD1 tudor domain containing 1
TESC tescalcin
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM51 transmembrane protein 51
TMEM53 transmembrane protein 53
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TUBA3D tubulin, alpha 3d
USP36 ubiquitin specific peptidase 36
VEGFB vascular endothelial growth factor B
VGF VGF nerve growth factor inducible
WDR25 WD repeat domain 25
WFDC2 WAP four-disulfide core domain 2
XAB2 XPA binding protein 2
ZC3H12A zinc finger CCCH-type containing 12A
ZFHX3 zinc finger homeobox 3
ZNF35 zinc finger protein 35
ZNF423 zinc finger protein 423
ZNF428 zinc finger protein 428
ZNF442 zinc finger protein 442
ZNF768 zinc finger protein 768