minaprine-1888 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the minaprine-1888 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
AKAP13 A kinase (PRKA) anchor protein 13
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
APLP1 amyloid beta (A4) precursor-like protein 1
ARFRP1 ADP-ribosylation factor related protein 1
ATAD5 ATPase family, AAA domain containing 5
AXIN1 axin 1
BICD1 bicaudal D homolog 1 (Drosophila)
C16ORF58 chromosome 16 open reading frame 58
C21ORF2 chromosome 21 open reading frame 2
CALML4 calmodulin-like 4
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CCDC85B coiled-coil domain containing 85B
CDC40 cell division cycle 40
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLEC16A C-type lectin domain family 16, member A
COL13A1 collagen, type XIII, alpha 1
CPN1 carboxypeptidase N, polypeptide 1
CSN2 casein beta
CTNNBIP1 catenin, beta interacting protein 1
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EHD1 EH-domain containing 1
EID1 EP300 interacting inhibitor of differentiation 1
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
ESRRA estrogen-related receptor alpha
FANCE Fanconi anemia, complementation group E
FBXO31 F-box protein 31
FSD1 fibronectin type III and SPRY domain containing 1
FZD8 frizzled class receptor 8
GBX2 gastrulation brain homeobox 2
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HEATR6 HEAT repeat containing 6
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL1R1 interleukin 1 receptor, type I
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KLF2 Kruppel-like factor 2
KLHL1 kelch-like family member 1
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRP3 low density lipoprotein receptor-related protein 3
MANBA mannosidase, beta A, lysosomal
MARK4 MAP/microtubule affinity-regulating kinase 4
MBD3 methyl-CpG binding domain protein 3
MPPE1 metallophosphoesterase 1
MTF2 metal response element binding transcription factor 2
MUC1 mucin 1, cell surface associated
MXD4 MAX dimerization protein 4
MYL10 myosin, light chain 10, regulatory
MYO9A myosin IXA
MYRF myelin regulatory factor
NAAA N-acylethanolamine acid amidase
NSUN5P1 NOP2/Sun domain family, member 5 pseudogene 1
NUBP2 nucleotide binding protein 2
NXT2 nuclear transport factor 2-like export factor 2
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PDLIM5 PDZ and LIM domain 5
PF4 platelet factor 4
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PKD1 polycystic kidney disease 1 (autosomal dominant)
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PQLC2 PQ loop repeat containing 2
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
RANBP3 RAN binding protein 3
RHOT2 ras homolog family member T2
RING1 ring finger protein 1
RPS11 ribosomal protein S11
SAFB2 scaffold attachment factor B2
SAMHD1 SAM domain and HD domain 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SRRM1 serine/arginine repetitive matrix 1
TBC1D17 TBC1 domain family, member 17
TCEA2 transcription elongation factor A (SII), 2
TCP11L1 t-complex 11, testis-specific-like 1
TDRD3 tudor domain containing 3
TDRKH tudor and KH domain containing
TLE3 transducin-like enhancer of split 3
TMEM97 transmembrane protein 97
TP53I11 tumor protein p53 inducible protein 11
TPI1 triosephosphate isomerase 1
TPRA1 transmembrane protein, adipocyte asscociated 1
TRIOBP TRIO and F-actin binding protein
UBOX5 U-box domain containing 5
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
USF2 upstream transcription factor 2, c-fos interacting
VIPR2 vasoactive intestinal peptide receptor 2
WDTC1 WD and tetratricopeptide repeats 1
ZC3H12A zinc finger CCCH-type containing 12A
ZDHHC14 zinc finger, DHHC-type containing 14
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF408 zinc finger protein 408
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
ACYP1 acylphosphatase 1, erythrocyte (common) type
ADGRG6 adhesion G protein-coupled receptor G6
AHR aryl hydrocarbon receptor
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
ARGLU1 arginine and glutamate rich 1
ATXN2 ataxin 2
BCL10 B-cell CLL/lymphoma 10
BRIX1 BRX1, biogenesis of ribosomes
C1D C1D nuclear receptor corepressor
C1ORF115 chromosome 1 open reading frame 115
CD151 CD151 molecule (Raph blood group)
CDC73 cell division cycle 73
CEP85 centrosomal protein 85kDa
CHML choroideremia-like (Rab escort protein 2)
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLCF1 cardiotrophin-like cytokine factor 1
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
COMMD10 COMM domain containing 10
CROT carnitine O-octanoyltransferase
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CTSO cathepsin O
CXCL6 chemokine (C-X-C motif) ligand 6
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DNASE1L1 deoxyribonuclease I-like 1
DOCK1 dedicator of cytokinesis 1
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
EXOC5 exocyst complex component 5
FAM114A2 family with sequence similarity 114, member A2
FAM172A family with sequence similarity 172, member A
FKBPL FK506 binding protein like
FUBP3 far upstream element (FUSE) binding protein 3
GALR3 galanin receptor 3
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
HAS2 hyaluronan synthase 2
HIST1H2BC histone cluster 1, H2bc
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
HOXC6 homeobox C6
HSPA4L heat shock 70kDa protein 4-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ISOC1 isochorismatase domain containing 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
JAK1 Janus kinase 1
KRT6A keratin 6A, type II
KRT75 keratin 75, type II
LZTR1 leucine-zipper-like transcription regulator 1
MAGT1 magnesium transporter 1
MAPK3 mitogen-activated protein kinase 3
MARC1 mitochondrial amidoxime reducing component 1
MEAF6 MYST/Esa1-associated factor 6
MEX3C mex-3 RNA binding family member C
MICU2 mitochondrial calcium uptake 2
MORC3 MORC family CW-type zinc finger 3
MPV17 MpV17 mitochondrial inner membrane protein
MT1HL1 metallothionein 1H-like 1
MYL12B myosin, light chain 12B, regulatory
NFE2L2 nuclear factor, erythroid 2-like 2
NUCB2 nucleobindin 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OSTM1 osteopetrosis associated transmembrane protein 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PARM1 prostate androgen-regulated mucin-like protein 1
PCNXL4 pecanex-like 4 (Drosophila)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PRCC papillary renal cell carcinoma (translocation-associated)
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PRSS23 protease, serine, 23
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAP1A RAP1A, member of RAS oncogene family
RCOR1 REST corepressor 1
RPE ribulose-5-phosphate-3-epimerase
RPL23AP7 ribosomal protein L23a pseudogene 7
RPS25 ribosomal protein S25
RRP1 ribosomal RNA processing 1
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
RSL24D1 ribosomal L24 domain containing 1
SDHAF3 succinate dehydrogenase complex assembly factor 3
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32
SLC38A6 solute carrier family 38, member 6
SLMO2 slowmo homolog 2 (Drosophila)
SNAI2 snail family zinc finger 2
SPAG1 sperm associated antigen 1
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1
STAU2 staufen double-stranded RNA binding protein 2
STXBP3 syntaxin binding protein 3
SURF2 surfeit 2
TBCC tubulin folding cofactor C
TBX3 T-box 3
TMEM123 transmembrane protein 123
TOP2B topoisomerase (DNA) II beta 180kDa
TRIM5 tripartite motif containing 5
TTI2 TELO2 interacting protein 2
UBA2 ubiquitin-like modifier activating enzyme 2
UGDH UDP-glucose 6-dehydrogenase
WDR11 WD repeat domain 11
XPOT exportin, tRNA
ZNF226 zinc finger protein 226