| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the minaprine-1888 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARFRP1 | ADP-ribosylation factor related protein 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| AXIN1 | axin 1 |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| C16ORF58 | chromosome 16 open reading frame 58 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CALML4 | calmodulin-like 4 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa |
| CCDC85B | coiled-coil domain containing 85B |
| CDC40 | cell division cycle 40 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLEC16A | C-type lectin domain family 16, member A |
| COL13A1 | collagen, type XIII, alpha 1 |
| CPN1 | carboxypeptidase N, polypeptide 1 |
| CSN2 | casein beta |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
| EHD1 | EH-domain containing 1 |
| EID1 | EP300 interacting inhibitor of differentiation 1 |
| EIF2S1 | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa |
| ESRRA | estrogen-related receptor alpha |
| FANCE | Fanconi anemia, complementation group E |
| FBXO31 | F-box protein 31 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| FZD8 | frizzled class receptor 8 |
| GBX2 | gastrulation brain homeobox 2 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HEATR6 | HEAT repeat containing 6 |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL1R1 | interleukin 1 receptor, type I |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KLF2 | Kruppel-like factor 2 |
| KLHL1 | kelch-like family member 1 |
| LETM1 | leucine zipper-EF-hand containing transmembrane protein 1 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MANBA | mannosidase, beta A, lysosomal |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MBD3 | methyl-CpG binding domain protein 3 |
| MPPE1 | metallophosphoesterase 1 |
| MTF2 | metal response element binding transcription factor 2 |
| MUC1 | mucin 1, cell surface associated |
| MXD4 | MAX dimerization protein 4 |
| MYL10 | myosin, light chain 10, regulatory |
| MYO9A | myosin IXA |
| MYRF | myelin regulatory factor |
| NAAA | N-acylethanolamine acid amidase |
| NSUN5P1 | NOP2/Sun domain family, member 5 pseudogene 1 |
| NUBP2 | nucleotide binding protein 2 |
| NXT2 | nuclear transport factor 2-like export factor 2 |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 |
| PDLIM5 | PDZ and LIM domain 5 |
| PF4 | platelet factor 4 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PQLC2 | PQ loop repeat containing 2 |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| RANBP3 | RAN binding protein 3 |
| RHOT2 | ras homolog family member T2 |
| RING1 | ring finger protein 1 |
| RPS11 | ribosomal protein S11 |
| SAFB2 | scaffold attachment factor B2 |
| SAMHD1 | SAM domain and HD domain 1 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa |
| SRRM1 | serine/arginine repetitive matrix 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TDRD3 | tudor domain containing 3 |
| TDRKH | tudor and KH domain containing |
| TLE3 | transducin-like enhancer of split 3 |
| TMEM97 | transmembrane protein 97 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TPI1 | triosephosphate isomerase 1 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRIOBP | TRIO and F-actin binding protein |
| UBOX5 | U-box domain containing 5 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| USF2 | upstream transcription factor 2, c-fos interacting |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF408 | zinc finger protein 408 |
| ZNF688 | zinc finger protein 688 |
| Symbol | Name |
|---|---|
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 |
| ACTR1B | ARP1 actin-related protein 1 homolog B, centractin beta (yeast) |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| AHR | aryl hydrocarbon receptor |
| APPL2 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 |
| ARGLU1 | arginine and glutamate rich 1 |
| ATXN2 | ataxin 2 |
| BCL10 | B-cell CLL/lymphoma 10 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| C1D | C1D nuclear receptor corepressor |
| C1ORF115 | chromosome 1 open reading frame 115 |
| CD151 | CD151 molecule (Raph blood group) |
| CDC73 | cell division cycle 73 |
| CEP85 | centrosomal protein 85kDa |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit |
| COMMD10 | COMM domain containing 10 |
| CROT | carnitine O-octanoyltransferase |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| CTSO | cathepsin O |
| CXCL6 | chemokine (C-X-C motif) ligand 6 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| DNASE1L1 | deoxyribonuclease I-like 1 |
| DOCK1 | dedicator of cytokinesis 1 |
| ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
| EXOC5 | exocyst complex component 5 |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FAM172A | family with sequence similarity 172, member A |
| FKBPL | FK506 binding protein like |
| FUBP3 | far upstream element (FUSE) binding protein 3 |
| GALR3 | galanin receptor 3 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) |
| HAS2 | hyaluronan synthase 2 |
| HIST1H2BC | histone cluster 1, H2bc |
| HNRNPH2 | heterogeneous nuclear ribonucleoprotein H2 (H') |
| HOXC6 | homeobox C6 |
| HSPA4L | heat shock 70kDa protein 4-like |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| ISOC1 | isochorismatase domain containing 1 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| JAK1 | Janus kinase 1 |
| KRT6A | keratin 6A, type II |
| KRT75 | keratin 75, type II |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAGT1 | magnesium transporter 1 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MEAF6 | MYST/Esa1-associated factor 6 |
| MEX3C | mex-3 RNA binding family member C |
| MICU2 | mitochondrial calcium uptake 2 |
| MORC3 | MORC family CW-type zinc finger 3 |
| MPV17 | MpV17 mitochondrial inner membrane protein |
| MT1HL1 | metallothionein 1H-like 1 |
| MYL12B | myosin, light chain 12B, regulatory |
| NFE2L2 | nuclear factor, erythroid 2-like 2 |
| NUCB2 | nucleobindin 2 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OSTM1 | osteopetrosis associated transmembrane protein 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PCNXL4 | pecanex-like 4 (Drosophila) |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PRCC | papillary renal cell carcinoma (translocation-associated) |
| PRKRA | protein kinase, interferon-inducible double stranded RNA dependent activator |
| PRSS23 | protease, serine, 23 |
| QTRTD1 | queuine tRNA-ribosyltransferase domain containing 1 |
| RAP1A | RAP1A, member of RAS oncogene family |
| RCOR1 | REST corepressor 1 |
| RPE | ribulose-5-phosphate-3-epimerase |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| RPS25 | ribosomal protein S25 |
| RRP1 | ribosomal RNA processing 1 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RSL24D1 | ribosomal L24 domain containing 1 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 |
| SLC38A6 | solute carrier family 38, member 6 |
| SLMO2 | slowmo homolog 2 (Drosophila) |
| SNAI2 | snail family zinc finger 2 |
| SPAG1 | sperm associated antigen 1 |
| SS18L1 | synovial sarcoma translocation gene on chromosome 18-like 1 |
| STAU2 | staufen double-stranded RNA binding protein 2 |
| STXBP3 | syntaxin binding protein 3 |
| SURF2 | surfeit 2 |
| TBCC | tubulin folding cofactor C |
| TBX3 | T-box 3 |
| TMEM123 | transmembrane protein 123 |
| TOP2B | topoisomerase (DNA) II beta 180kDa |
| TRIM5 | tripartite motif containing 5 |
| TTI2 | TELO2 interacting protein 2 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 |
| UGDH | UDP-glucose 6-dehydrogenase |
| WDR11 | WD repeat domain 11 |
| XPOT | exportin, tRNA |
| ZNF226 | zinc finger protein 226 |