| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the minaprine-4230 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| AFF2 | AF4/FMR2 family, member 2 |
| AGFG2 | ArfGAP with FG repeats 2 |
| APOE | apolipoprotein E |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CCL24 | chemokine (C-C motif) ligand 24 |
| CCR7 | chemokine (C-C motif) receptor 7 |
| CDH19 | cadherin 19, type 2 |
| CDK2 | cyclin-dependent kinase 2 |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CHRM2 | cholinergic receptor, muscarinic 2 |
| CNGB1 | cyclic nucleotide gated channel beta 1 |
| CNTNAP2 | contactin associated protein-like 2 |
| COL14A1 | collagen, type XIV, alpha 1 |
| COL4A6 | collagen, type IV, alpha 6 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CYSLTR1 | cysteinyl leukotriene receptor 1 |
| DCAF15 | DDB1 and CUL4 associated factor 15 |
| DDO | D-aspartate oxidase |
| DOK4 | docking protein 4 |
| DOPEY2 | dopey family member 2 |
| DST | dystonin |
| ELAC1 | elaC ribonuclease Z 1 |
| EPHB1 | EPH receptor B1 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FBXO22 | F-box protein 22 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FOXF1 | forkhead box F1 |
| FZD1 | frizzled class receptor 1 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GFER | growth factor, augmenter of liver regeneration |
| GPNMB | glycoprotein (transmembrane) nmb |
| GRM8 | glutamate receptor, metabotropic 8 |
| GSTA1 | glutathione S-transferase alpha 1 |
| HGD | homogentisate 1,2-dioxygenase |
| HOOK1 | hook microtubule-tethering protein 1 |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic |
| IGF2-AS | IGF2 antisense RNA |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| KALRN | kalirin, RhoGEF kinase |
| KCNH6 | potassium channel, voltage gated eag related subfamily H, member 6 |
| KDM5B | lysine (K)-specific demethylase 5B |
| KIF26B | kinesin family member 26B |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LRRC75B | leucine rich repeat containing 75B |
| MAP2 | microtubule-associated protein 2 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| METTL7A | methyltransferase like 7A |
| MFAP5 | microfibrillar associated protein 5 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MRC2 | mannose receptor, C type 2 |
| NCAN | neurocan |
| NOL4 | nucleolar protein 4 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPR1 | natriuretic peptide receptor 1 |
| NPTXR | neuronal pentraxin receptor |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| PCDH8 | protocadherin 8 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PRAF2 | PRA1 domain family, member 2 |
| PRDM14 | PR domain containing 14 |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PTK2B | protein tyrosine kinase 2 beta |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| RAB6A | RAB6A, member RAS oncogene family |
| RCE1 | Ras converting CAAX endopeptidase 1 |
| RGS5 | regulator of G-protein signaling 5 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RNF8 | ring finger protein 8, E3 ubiquitin protein ligase |
| SACK1E | scaffolding CK1 anchoring protein E |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) |
| SLC15A1 | solute carrier family 15 (oligopeptide transporter), member 1 |
| SLC39A9 | solute carrier family 39, member 9 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SNTB2 | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) |
| SP2 | Sp2 transcription factor |
| SRF | serum response factor (c-fos serum response element-binding transcription factor) |
| SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 |
| SUGP1 | SURP and G patch domain containing 1 |
| SVIL | supervillin |
| SYT5 | synaptotagmin V |
| TBX6 | T-box 6 |
| TPSAB1 | tryptase alpha/beta 1 |
| TRIL | TLR4 interactor with leucine-rich repeats |
| TRIM29 | tripartite motif containing 29 |
| TRIM31 | tripartite motif containing 31 |
| TRPC3 | transient receptor potential cation channel, subfamily C, member 3 |
| VAX2 | ventral anterior homeobox 2 |
| ZNF235 | zinc finger protein 235 |
| ZNF415 | zinc finger protein 415 |
| ZNF484 | zinc finger protein 484 |
| Symbol | Name |
|---|---|
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ADAM2 | ADAM metallopeptidase domain 2 |
| ALOX12 | arachidonate 12-lipoxygenase |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BDNF | brain-derived neurotrophic factor |
| BEX4 | brain expressed, X-linked 4 |
| CA9 | carbonic anhydrase IX |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CBX8 | chromobox homolog 8 |
| CCNJL | cyclin J-like |
| CD68 | CD68 molecule |
| CD70 | CD70 molecule |
| CEP85 | centrosomal protein 85kDa |
| CFAP45 | cilia and flagella associated protein 45 |
| CHMP6 | charged multivesicular body protein 6 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLDN1 | claudin 1 |
| COMP | cartilage oligomeric matrix protein |
| CPNE7 | copine VII |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CUL9 | cullin 9 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ERCC2 | excision repair cross-complementation group 2 |
| ERCC4 | excision repair cross-complementation group 4 |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FKBPL | FK506 binding protein like |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GPR39 | G protein-coupled receptor 39 |
| GRAMD1C | GRAM domain containing 1C |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H4E | histone cluster 1, H4e |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFNA17 | interferon, alpha 17 |
| IL4R | interleukin 4 receptor |
| ITPKA | inositol-trisphosphate 3-kinase A |
| JUNB | jun B proto-oncogene |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOC100287590 | uncharacterized LOC100287590 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LRRC37A4P | leucine rich repeat containing 37, member A4, pseudogene |
| MATN3 | matrilin 3 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MVP | major vault protein |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NOTCH4 | notch 4 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PLD3 | phospholipase D family, member 3 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PRR4 | proline rich 4 (lacrimal) |
| PRR7 | proline rich 7 (synaptic) |
| RAB36 | RAB36, member RAS oncogene family |
| RBM19 | RNA binding motif protein 19 |
| RNF122 | ring finger protein 122 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SCG5 | secretogranin V |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SLCO1B1 | solute carrier organic anion transporter family, member 1B1 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| THBS3 | thrombospondin 3 |
| THRB | thyroid hormone receptor, beta |
| TLR2 | toll-like receptor 2 |
| TMEM209 | transmembrane protein 209 |
| TMEM242 | transmembrane protein 242 |
| TMEM53 | transmembrane protein 53 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TRIM25 | tripartite motif containing 25 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| WDR18 | WD repeat domain 18 |
| ZNF227 | zinc finger protein 227 |
| ZNF74 | zinc finger protein 74 |
| ZNF778 | zinc finger protein 778 |