minaprine-4814 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the minaprine-4814 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACTN2 actinin, alpha 2
ADCY10 adenylate cyclase 10 (soluble)
AJAP1 adherens junctions associated protein 1
AKAP7 A kinase (PRKA) anchor protein 7
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
ATP10B ATPase, class V, type 10B
ATXN2L ataxin 2-like
ATXN3 ataxin 3
BTNL2 butyrophilin-like 2
C3ORF18 chromosome 3 open reading frame 18
C6ORF10 chromosome 6 open reading frame 10
CDC14B cell division cycle 14B
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CFAP45 cilia and flagella associated protein 45
CHML choroideremia-like (Rab escort protein 2)
CORT cortistatin
CTBP2 C-terminal binding protein 2
CTNS cystinosin, lysosomal cystine transporter
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DCTN1 dynactin 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DSG3 desmoglein 3
EMC1 ER membrane protein complex subunit 1
EN2 engrailed homeobox 2
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EPS8L1 EPS8-like 1
EXOC7 exocyst complex component 7
FBXL18 F-box and leucine-rich repeat protein 18
GBP1 guanylate binding protein 1, interferon-inducible
GLIPR1 GLI pathogenesis-related 1
GPATCH2L G patch domain containing 2-like
GSK3A glycogen synthase kinase 3 alpha
HOXB2 homeobox B2
HPSE2 heparanase 2 (inactive)
ICAM1 intercellular adhesion molecule 1
IDS iduronate 2-sulfatase
IL11RA interleukin 11 receptor, alpha
ING2 inhibitor of growth family, member 2
INHBA inhibin, beta A
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
ITGA6 integrin, alpha 6
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LEFTY1 left-right determination factor 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
MBD2 methyl-CpG binding domain protein 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED18 mediator complex subunit 18
METTL7A methyltransferase like 7A
MFAP2 microfibrillar-associated protein 2
MFAP3L microfibrillar-associated protein 3-like
MMP3 matrix metallopeptidase 3
NBL1 neuroblastoma 1, DAN family BMP antagonist
NEB nebulin
NFX1 nuclear transcription factor, X-box binding 1
NNAT neuronatin
NPTX1 neuronal pentraxin I
OGDHL oxoglutarate dehydrogenase-like
ONECUT2 one cut homeobox 2
OR10H2 olfactory receptor, family 10, subfamily H, member 2
OSBPL10 oxysterol binding protein-like 10
PARD6B par-6 family cell polarity regulator beta
PCNX pecanex homolog (Drosophila)
PDE12 phosphodiesterase 12
PHC3 polyhomeotic homolog 3 (Drosophila)
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PLCD1 phospholipase C, delta 1
PPARG peroxisome proliferator-activated receptor gamma
RARA retinoic acid receptor, alpha
RBBP4 retinoblastoma binding protein 4
RERE arginine-glutamic acid dipeptide (RE) repeats
RIMS2 regulating synaptic membrane exocytosis 2
RUSC2 RUN and SH3 domain containing 2
SCN11A sodium channel, voltage gated, type XI alpha subunit
SIGLEC6 sialic acid binding Ig-like lectin 6
SIRT5 sirtuin 5
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1
SLC25A30 solute carrier family 25, member 30
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SNCAIP synuclein, alpha interacting protein
STIM1 stromal interaction molecule 1
SUGP1 SURP and G patch domain containing 1
TM4SF5 transmembrane 4 L six family member 5
TPMT thiopurine S-methyltransferase
TRD T cell receptor delta locus
TRIP11 thyroid hormone receptor interactor 11
TTC28 tetratricopeptide repeat domain 28
UTRN utrophin
VWA5A von Willebrand factor A domain containing 5A
ZIM2 zinc finger, imprinted 2
ZNF224 zinc finger protein 224
ZNF259P1 zinc finger protein 259 pseudogene 1
ZNF442 zinc finger protein 442
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ADAM15 ADAM metallopeptidase domain 15
ADCY6 adenylate cyclase 6
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATAD5 ATPase family, AAA domain containing 5
BEX4 brain expressed, X-linked 4
BRMS1 breast cancer metastasis suppressor 1
C14ORF93 chromosome 14 open reading frame 93
C2ORF44 chromosome 2 open reading frame 44
C7ORF43 chromosome 7 open reading frame 43
CAPN5 calpain 5
CAPRIN2 caprin family member 2
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC85C coiled-coil domain containing 85C
CD302 CD302 molecule
CENPJ centromere protein J
CEP85 centrosomal protein 85kDa
CHKA choline kinase alpha
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
COQ6 coenzyme Q6 monooxygenase
CORO7 coronin 7
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRIP1 cysteine-rich protein 1 (intestinal)
CTSD cathepsin D
DDIT3 DNA-damage-inducible transcript 3
FAM184A family with sequence similarity 184, member A
FAN1 FANCD2/FANCI-associated nuclease 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FKBPL FK506 binding protein like
GEMIN8 gem (nuclear organelle) associated protein 8
GPX2 glutathione peroxidase 2
GRB7 growth factor receptor-bound protein 7
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HELZ helicase with zinc finger
HIST1H2BJ histone cluster 1, H2bj
HMOX1 heme oxygenase 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFT46 intraflagellar transport 46
INTS9 integrator complex subunit 9
ISOC2 isochorismatase domain containing 2
JMJD4 jumonji domain containing 4
KLC2 kinesin light chain 2
KRT13 keratin 13, type I
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MATK megakaryocyte-associated tyrosine kinase
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MPDU1 mannose-P-dolichol utilization defect 1
MVP major vault protein
NR1H3 nuclear receptor subfamily 1, group H, member 3
NT5DC3 5'-nucleotidase domain containing 3
ODF2 outer dense fiber of sperm tails 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PANK4 pantothenate kinase 4
PCDHB3 protocadherin beta 3
PGP phosphoglycolate phosphatase
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRR14L proline rich 14-like
PRSS8 protease, serine, 8
RAB5B RAB5B, member RAS oncogene family
RBM38 RNA binding motif protein 38
ROM1 retinal outer segment membrane protein 1
RPAP2 RNA polymerase II associated protein 2
SAV1 salvador family WW domain containing protein 1
SCPEP1 serine carboxypeptidase 1
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STK16 serine/threonine kinase 16
SYTL2 synaptotagmin-like 2
TBC1D17 TBC1 domain family, member 17
TLN1 talin 1
TMEM53 transmembrane protein 53
TNRC6B trinucleotide repeat containing 6B
TOM1 target of myb1 (chicken)
TSPAN1 tetraspanin 1
TSPO translocator protein (18kDa)
TUBA3D tubulin, alpha 3d
UBTF upstream binding transcription factor, RNA polymerase I
UBXN6 UBX domain protein 6
USB1 U6 snRNA biogenesis 1
USP20 ubiquitin specific peptidase 20
WDR18 WD repeat domain 18
ZMAT5 zinc finger, matrin-type 5
ZNF219 zinc finger protein 219
ZNF276 zinc finger protein 276
ZNF446 zinc finger protein 446
ZNF692 zinc finger protein 692
ZNF747 zinc finger protein 747