mir31 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description microRNA 31|microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 407035)
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Genes

43 genes co-occuring with the biological term mir31 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
BRAF B-Raf proto-oncogene, serine/threonine kinase
C11ORF30 chromosome 11 open reading frame 30
CCND1 cyclin D1
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CREG1 cellular repressor of E1A-stimulated genes 1
DICER1 dicer 1, ribonuclease type III
DMD dystrophin
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FOXP3 forkhead box P3
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
ICAM1 intercellular adhesion molecule 1
IL2 interleukin 2
KSR2 kinase suppressor of ras 2
LATS2 large tumor suppressor kinase 2
MIR125A microRNA 125a
MIR130B microRNA 130b
MIR155 microRNA 155
MIR17 microRNA 17
MIR182 microRNA 182
MIR203A microRNA 203a
MIR205 microRNA 205
MIR21 microRNA 21
MIR31 microRNA 31
MIR375 microRNA 375
MIR564 microRNA 564
MIR584 microRNA 584
PRKCE protein kinase C, epsilon
PTEN phosphatase and tensin homolog
RDX radixin
RHOA ras homolog family member A
RHOBTB1 Rho-related BTB domain containing 1
SATB2 SATB homeobox 2
SELE selectin E
SP7 Sp7 transcription factor
TIAM1 T-cell lymphoma invasion and metastasis 1
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TP53 tumor protein p53
TP63 tumor protein p63
WASF3 WAS protein family, member 3
YAP1 Yes-associated protein 1