mitochondrial prohibitin complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A complex composed of two proteins, prohibitin 1 and prohibitin 2 (PHB1/PHB-1 and PHB2/PHB-2) that is highly conserved amongst eukaryotes and associated with the inner mitochondrial membrane. The mitochondrial prohibitin complex is a macromolecular supercomplex composed of repeating heterodimeric subunits of PHB1 and PHB2. The mitochondrial prohibitin complex plays a role in a number of biological processes, including mitochondrial biogenesis and function, development, replicative senescence, and cell death. (Gene Ontology, GO_0035632)
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8 proteins co-occuring with the mitochondrial prohibitin complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
PHB prohibitin 1.82186
PHB2 prohibitin 2 1.30981
SPHK2 sphingosine kinase 2 0.979044
PPP1R9A protein phosphatase 1, regulatory subunit 9A 0.874567
SEPT9 septin 9 0.851583
SPHK1 sphingosine kinase 1 0.672026
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.426318
TFAM transcription factor A, mitochondrial 0.312971