mitochondrial respiratory chain complex i Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. (Gene Ontology, GO_0005747)
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46 proteins co-occuring with the mitochondrial respiratory chain complex i cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 0.972747
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.916709
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.893018
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 0.886551
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 0.874107
NDUFA4 NDUFA4, mitochondrial complex associated 0.802938
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 0.789649
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa 0.666394
PLIN5 perilipin 5 0.662072
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 0.659913
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 0.639717
NKX2-5 NK2 homeobox 5 0.611201
GDAP1 ganglioside induced differentiation associated protein 1 0.604017
CCDC130 coiled-coil domain containing 130 0.586361
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 0.537416
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 0.525522
NR3C2 nuclear receptor subfamily 3, group C, member 2 0.49661
NOX4 NADPH oxidase 4 0.48287
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.48005
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.477233
GLRX glutaredoxin (thioltransferase) 0.465198
CS citrate synthase 0.452825
MTERF1 mitochondrial transcription termination factor 1 0.449643
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.424353
RCC1 regulator of chromosome condensation 1 0.414164
PARK7 parkinson protein 7 0.41221
ELAVL3 ELAV like neuron-specific RNA binding protein 3 0.369684
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 0.36204
EDN1 endothelin 1 0.352142
PNPLA2 patatin-like phospholipase domain containing 2 0.343042
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.308122
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 0.299197
LRRK2 leucine-rich repeat kinase 2 0.293637
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.292527
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.281085
PLIN1 perilipin 1 0.268237
CAT catalase 0.265311
LIPE lipase, hormone-sensitive 0.25438
PLIN2 perilipin 2 0.249302
FXN frataxin 0.24894
CYBA cytochrome b-245, alpha polypeptide 0.247492
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.196669
COX5A cytochrome c oxidase subunit Va 0.195681
IFNB1 interferon, beta 1, fibroblast 0.190814
SOD2 superoxide dismutase 2, mitochondrial 0.179752
GATA4 GATA binding protein 4 0.170888