mitosis Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell. (Gene Ontology, GO_0007067)
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Genes

447 genes co-occuring with the biological term mitosis in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
ABI1 abl-interactor 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACTN4 actinin, alpha 4
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ADD1 adducin 1 (alpha)
AHCTF1 AT hook containing transcription factor 1
AKAP12 A kinase (PRKA) anchor protein 12
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANAPC11 anaphase promoting complex subunit 11
APC adenomatous polyposis coli
APOE apolipoprotein E
AR androgen receptor
ARF6 ADP-ribosylation factor 6
ARHGAP35 Rho GTPase activating protein 35
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
ATXN1 ataxin 1
AURKA aurora kinase A
AURKB aurora kinase B
AURKC aurora kinase C
BAG6 BCL2-associated athanogene 6
BANF1 barrier to autointegration factor 1
BARD1 BRCA1 associated RING domain 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCR breakpoint cluster region
BECN1 beclin 1, autophagy related
BID BH3 interacting domain death agonist
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
BLM Bloom syndrome, RecQ helicase-like
BMPR1B bone morphogenetic protein receptor, type IB
BORA bora, aurora kinase A activator
BRCA2 breast cancer 2, early onset
BRD4 bromodomain containing 4
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAPN2 calpain 2, (m/II) large subunit
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CAV2 caveolin 2
CBX5 chromobox homolog 5
CC2D1A coiled-coil and C2 domain containing 1A
CCNA1 cyclin A1
CCNA2 cyclin A2
CCNB1 cyclin B1
CCNB2 cyclin B2
CCNE1 cyclin E1
CCNF cyclin F
CCNT1 cyclin T1
CCP110 centriolar coiled coil protein 110kDa
CCSER1 coiled-coil serine-rich protein 1
CDC14A cell division cycle 14A
CDC14B cell division cycle 14B
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
CDC27 cell division cycle 27
CDC6 cell division cycle 6
CDC7 cell division cycle 7
CDCA8 cell division cycle associated 8
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK1 cyclin-dependent kinase 1
CDK11A cyclin-dependent kinase 11A
CDK16 cyclin-dependent kinase 16
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDK9 cyclin-dependent kinase 9
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN3 cyclin-dependent kinase inhibitor 3
CELF2 CUGBP, Elav-like family member 2
CENPA centromere protein A
CENPB centromere protein B, 80kDa
CENPE centromere protein E, 312kDa
CENPF centromere protein F, 350/400kDa
CENPN centromere protein N
CENPT centromere protein T
CENPW centromere protein W
CEP192 centrosomal protein 192kDa
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CKAP2 cytoskeleton associated protein 2
CKAP4 cytoskeleton-associated protein 4
CKAP5 cytoskeleton associated protein 5
CKB creatine kinase, brain
CLASP2 cytoplasmic linker associated protein 2
CLSPN claspin
CLTA clathrin, light chain A
CLTC clathrin, heavy chain (Hc)
CNTRL centriolin
CNTROB centrobin, centrosomal BRCA2 interacting protein
COIL coilin
COPS5 COP9 signalosome subunit 5
CREB1 cAMP responsive element binding protein 1
CSDE1 cold shock domain containing E1, RNA-binding
CTBP1 C-terminal binding protein 1
CTBP2 C-terminal binding protein 2
CTCF CCCTC-binding factor (zinc finger protein)
CTCFL CCCTC-binding factor (zinc finger protein)-like
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTTN cortactin
CUEDC2 CUE domain containing 2
CUL3 cullin 3
CUL4A cullin 4A
CUL4B cullin 4B
CUX1 cut-like homeobox 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAXX death-domain associated protein
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
DIAPH3 diaphanous-related formin 3
DLG1 discs, large homolog 1 (Drosophila)
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DNM1L dynamin 1-like
DSN1 DSN1, MIS12 kinetochore complex component
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNLL1 dynein, light chain, LC8-type 1
E2F1 E2F transcription factor 1
E2F4 E2F transcription factor 4, p107/p130-binding
ECT2 epithelial cell transforming 2
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EMD emerin
EPB41 erythrocyte membrane protein band 4.1
ERCC3 excision repair cross-complementation group 3
ERCC4 excision repair cross-complementation group 4
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
EVI5 ecotropic viral integration site 5
FADD Fas (TNFRSF6)-associated via death domain
FAM110B family with sequence similarity 110, member B
FANCD2 Fanconi anemia, complementation group D2
FANCI Fanconi anemia, complementation group I
FANCM Fanconi anemia, complementation group M
FBXL2 F-box and leucine-rich repeat protein 2
FBXL7 F-box and leucine-rich repeat protein 7
FBXO5 F-box protein 5
FBXW5 F-box and WD repeat domain containing 5
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FHOD1 formin homology 2 domain containing 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXM1 forkhead box M1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GADD45G growth arrest and DNA-damage-inducible, gamma
GAK cyclin G associated kinase
GAS2L3 growth arrest-specific 2 like 3
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GJB1 gap junction protein, beta 1, 32kDa
GMNN geminin, DNA replication inhibitor
GPSM2 G-protein signaling modulator 2
GSG2 germ cell associated 2 (haspin)
GSK3B glycogen synthase kinase 3 beta
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
H2AFX H2A histone family, member X
H2AFY H2A histone family, member Y
H2AFZ H2A histone family, member Z
HCFC1 host cell factor C1
HDAC3 histone deacetylase 3
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
HIP1R huntingtin interacting protein 1 related
HIST1H1B histone cluster 1, H1b
HIST2H3C histone cluster 2, H3c
HIST4H4 histone cluster 4, H4
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HSF1 heat shock transcription factor 1
HSF2 heat shock transcription factor 2
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPB1 heat shock 27kDa protein 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGFBP4 insulin-like growth factor binding protein 4
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
ILF3 interleukin enhancer binding factor 3, 90kDa
ILK integrin-linked kinase
INCENP inner centromere protein antigens 135/155kDa
INO80 INO80 complex subunit
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JUNB jun B proto-oncogene
KAT2B K(lysine) acetyltransferase 2B
KDM1A lysine (K)-specific demethylase 1A
KDM2A lysine (K)-specific demethylase 2A
KIF11 kinesin family member 11
KIF2A kinesin heavy chain member 2A
KIF2B kinesin family member 2B
KIF2C kinesin family member 2C
KIF3A kinesin family member 3A
KIF3B kinesin family member 3B
KIF4A kinesin family member 4A
KIFAP3 kinesin-associated protein 3
KIFC1 kinesin family member C1
KLF4 Kruppel-like factor 4 (gut)
KLF5 Kruppel-like factor 5 (intestinal)
KLHL21 kelch-like family member 21
KNSTRN kinetochore-localized astrin/SPAG5 binding protein
KRAS Kirsten rat sarcoma viral oncogene homolog
LATS1 large tumor suppressor kinase 1
LBR lamin B receptor
LCMT1 leucine carboxyl methyltransferase 1
LIMD1 LIM domains containing 1
LIMK1 LIM domain kinase 1
LIN9 lin-9 DREAM MuvB core complex component
LMNA lamin A/C
LMNB1 lamin B1
LMNB2 lamin B2
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAD2L1BP MAD2L1 binding protein
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MAP2K1 mitogen-activated protein kinase kinase 1
MAP9 microtubule-associated protein 9
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MAPT microtubule-associated protein tau
MCL1 myeloid cell leukemia 1
MCTS1 malignant T cell amplified sequence 1
MDC1 mediator of DNA-damage checkpoint 1
MECOM MDS1 and EVI1 complex locus
MIS12 MIS12 kinetochore complex component
MKI67 marker of proliferation Ki-67
MPLKIP M-phase specific PLK1 interacting protein
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTUS2 microtubule associated tumor suppressor candidate 2
MYB v-myb avian myeloblastosis viral oncogene homolog
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
NAT10 N-acetyltransferase 10 (GCN5-related)
NCAPG non-SMC condensin I complex, subunit G
NCOA3 nuclear receptor coactivator 3
NDC80 NDC80 kinetochore complex component
NDE1 nudE neurodevelopment protein 1
NDRG1 N-myc downstream regulated 1
NEDD1 neural precursor cell expressed, developmentally down-regulated 1
NEK2 NIMA-related kinase 2
NEK3 NIMA-related kinase 3
NEK6 NIMA-related kinase 6
NEK7 NIMA-related kinase 7
NEK9 NIMA-related kinase 9
NET1 neuroepithelial cell transforming 1
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NIN ninein (GSK3B interacting protein)
NONO non-POU domain containing, octamer-binding
NOTCH1 notch 1
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NSUN2 NOP2/Sun RNA methyltransferase family, member 2
NUDC nudC nuclear distribution protein
NUF2 NUF2, NDC80 kinetochore complex component
NUMA1 nuclear mitotic apparatus protein 1
NUP107 nucleoporin 107kDa
NUP153 nucleoporin 153kDa
NUP160 nucleoporin 160kDa
NUP62 nucleoporin 62kDa
ODF2 outer dense fiber of sperm tails 2
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OIP5 Opa interacting protein 5
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARP1 poly (ADP-ribose) polymerase 1
PCM1 pericentriolar material 1
PCNT pericentrin
PEG3 paternally expressed 3
PGR progesterone receptor
PGRMC1 progesterone receptor membrane component 1
PHB2 prohibitin 2
PHF13 PHD finger protein 13
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PKN2 protein kinase N2
PLK1 polo-like kinase 1
PLK3 polo-like kinase 3
POGZ pogo transposable element with ZNF domain
POSTN periostin, osteoblast specific factor
POU2F1 POU class 2 homeobox 1
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R10 protein phosphatase 1, regulatory subunit 10
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2
PPP1R7 protein phosphatase 1, regulatory subunit 7
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PRPF19 pre-mRNA processing factor 19
PRPF4 pre-mRNA processing factor 4
PRR14 proline rich 14
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PTEN phosphatase and tensin homolog
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PTPRA protein tyrosine phosphatase, receptor type, A
PTTG1 pituitary tumor-transforming 1
PUM2 pumilio RNA-binding family member 2
RACGAP1 Rac GTPase activating protein 1
RAD21 RAD21 homolog (S. pombe)
RAE1 ribonucleic acid export 1
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RALBP1 ralA binding protein 1
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RAN RAN, member RAS oncogene family
RANBP1 RAN binding protein 1
RANBP2 RAN binding protein 2
RAP1A RAP1A, member of RAS oncogene family
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
RB1 retinoblastoma 1
RBM3 RNA binding motif (RNP1, RRM) protein 3
RCC2 regulator of chromosome condensation 2
REEP3 receptor accessory protein 3
REEP4 receptor accessory protein 4
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RHOA ras homolog family member A
RHOD ras homolog family member D
RMRP RNA component of mitochondrial RNA processing endoribonuclease
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RPA1 replication protein A1, 70kDa
RPA2 replication protein A2, 32kDa
RPS3 ribosomal protein S3
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPTOR regulatory associated protein of MTOR, complex 1
RUNX2 runt-related transcription factor 2
RUVBL2 RuvB-like AAA ATPase 2
S1PR5 sphingosine-1-phosphate receptor 5
SEC16A SEC16 homolog A (S. cerevisiae)
SEC23A Sec23 homolog A (S. cerevisiae)
SEC24C SEC24 family member C
SENP1 SUMO1/sentrin specific peptidase 1
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SENP5 SUMO1/sentrin specific peptidase 5
SEPT2 septin 2
SETD8P1 SET domain containing 8 pseudogene 1
SGOL1 shugoshin-like 1 (S. pombe)
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SIAH1 siah E3 ubiquitin protein ligase 1
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SIRT7 sirtuin 7
SKA3 spindle and kinetochore associated complex subunit 3
SKI SKI proto-oncogene
SKP1 S-phase kinase-associated protein 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLPI secretory leukocyte peptidase inhibitor
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMC5 structural maintenance of chromosomes 5
SMN1 survival of motor neuron 1, telomeric
SNRPE small nuclear ribonucleoprotein polypeptide E
SNX18 sorting nexin 18
SNX33 sorting nexin 33
SNX9 sorting nexin 9
SP1 Sp1 transcription factor
SP3 Sp3 transcription factor
SPAG5 sperm associated antigen 5
SPP1 secreted phosphoprotein 1
SPRR1B small proline-rich protein 1B
SREBF1 sterol regulatory element binding transcription factor 1
SRI sorcin
SSH1 slingshot protein phosphatase 1
SSRP1 structure specific recognition protein 1
SSU72 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)
STIL SCL/TAL1 interrupting locus
STIM1 stromal interaction molecule 1
STMN1 stathmin 1
SUMO1 small ubiquitin-like modifier 1
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SYMPK symplekin
TACC2 transforming, acidic coiled-coil containing protein 2
TBCB tubulin folding cofactor B
TBK1 TANK-binding kinase 1
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TGFB1 transforming growth factor, beta 1
TLK1 tousled-like kinase 1
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TOP1 topoisomerase (DNA) I
TOP2A topoisomerase (DNA) II alpha 170kDa
TOP3A topoisomerase (DNA) III alpha
TOPBP1 topoisomerase (DNA) II binding protein 1
TOX4 TOX high mobility group box family member 4
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP73 tumor protein p73
TPP2 tripeptidyl peptidase II
TPPP3 tubulin polymerization-promoting protein family member 3
TPX2 TPX2, microtubule-associated
TRIM33 tripartite motif containing 33
TROAP trophinin associated protein
TTC28 tetratricopeptide repeat domain 28
TTK TTK protein kinase
TTLL12 tubulin tyrosine ligase-like family member 12
TUBB tubulin, beta class I
TUBB4A tubulin, beta 4A class IVa
TUBG1 tubulin, gamma 1
UBE2C ubiquitin-conjugating enzyme E2C
UBE2K ubiquitin-conjugating enzyme E2K
UBE3A ubiquitin protein ligase E3A
UBE4A ubiquitination factor E4A
UBE4B ubiquitination factor E4B
UBXN2B UBX domain protein 2B
UFD1L ubiquitin fusion degradation 1 like (yeast)
UIMC1 ubiquitin interaction motif containing 1
USO1 USO1 vesicle transport factor
USP37 ubiquitin specific peptidase 37
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VIM vimentin
WAPAL wings apart-like homolog (Drosophila)
WAS Wiskott-Aldrich syndrome
WDR82 WD repeat domain 82
WEE1 WEE1 G2 checkpoint kinase
WWC1 WW and C2 domain containing 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPO1 exportin 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZBTB33 zinc finger and BTB domain containing 33
ZC3HC1 zinc finger, C3HC-type containing 1
ZNF365 zinc finger protein 365