mitotic G2/M transition checkpoint Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase as part of a mitotic cell cycle. (Gene Ontology, GO_0044818)
External Link http://amigo.geneontology.org/amigo/term/GO:0044818
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Genes

49 genes participating in the mitotic G2/M transition checkpoint biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ABRAXAS1 abraxas 1, BRCA1 A complex subunit
ARTN artemin
ATM ATM serine/threonine kinase
BABAM1 BRISC and BRCA1 A complex member 1
BABAM2 BRISC and BRCA1 A complex member 2
BARD1 BRCA1 associated RING domain 1
BLM Bloom syndrome, RecQ helicase-like
BRCA1 breast cancer 1, early onset
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
BRSK1 BR serine/threonine kinase 1
CDC6 cell division cycle 6
CDK1 cyclin-dependent kinase 1
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDPF1 cysteine-rich, DPF motif domain containing 1
CHEK1 checkpoint kinase 1
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CLSPN claspin
DONSON downstream neighbor of SON
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
ETAA1 Ewing tumor-associated antigen 1
FOXN3 forkhead box N3
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
HUS1 HUS1 checkpoint homolog (S. pombe)
HUS1B HUS1 checkpoint homolog b (S. pombe)
INIP INTS3 and NABP interacting protein
INTS3 integrator complex subunit 3
MRE11 MRE11 homolog, double strand break repair nuclease
MRNIP MRN complex interacting protein
NABP1 nucleic acid binding protein 1
NABP2 nucleic acid binding protein 2
NAE1 NEDD8 activating enzyme E1 subunit 1
NOP53 NOP53 ribosome biogenesis factor
PABIR1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1
PLK1 polo-like kinase 1
RAD17 RAD17 homolog (S. pombe)
RAD50 RAD50 homolog (S. cerevisiae)
RBBP8 retinoblastoma binding protein 8
RINT1 RAD50 interactor 1
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene)
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
TAOK1 TAO kinase 1
TAOK2 TAO kinase 2
TAOK3 TAO kinase 3
TICRR TOPBP1-interacting checkpoint and replication regulator
TOPBP1 topoisomerase (DNA) II binding protein 1
TRIM39 tripartite motif containing 39
UIMC1 ubiquitin interaction motif containing 1
ZNF367 zinc finger protein 367
ZNF830 zinc finger protein 830