mitotic spindle checkpoint signaling Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description A mitotic cell cycle checkpoint that originates from the spindle and delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and oriented, the completion of anaphase until chromosomes are attached to the spindle, or mitotic exit and cytokinesis when the spindle does not form. (Gene Ontology, GO_0071174)
External Link http://amigo.geneontology.org/amigo/term/GO_0071174
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Genes

27 genes participating in the mitotic spindle checkpoint signaling biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
APC adenomatous polyposis coli
ATM ATM serine/threonine kinase
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
CDC20 cell division cycle 20
CENPF centromere protein F, 350/400kDa
HASPIN histone H3 associated protein kinase
IK IK cytokine, down-regulator of HLA II
KLHL22 kelch-like family member 22
KNTC1 kinetochore associated 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
NDC80 NDC80 kinetochore complex component
NUF2 NUF2, NDC80 kinetochore complex component
PLK1 polo-like kinase 1
SPC24 SPC24, NDC80 kinetochore complex component
SPC25 SPC25, NDC80 kinetochore complex component
TEX14 testis expressed 14
TPR translocated promoter region, nuclear basket protein
TRIP13 thyroid hormone receptor interactor 13
TTK TTK protein kinase
ZNF207 zinc finger protein 207
ZW10 zw10 kinetochore protein
ZWILCH zwilch kinetochore protein
ZWINT ZW10 interacting kinetochore protein