| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the mitoxantrone-3232 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ADM | adrenomedullin |
| AHNAK | AHNAK nucleoprotein |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| ANPEP | alanyl (membrane) aminopeptidase |
| APOE | apolipoprotein E |
| ARHGEF15 | Rho guanine nucleotide exchange factor (GEF) 15 |
| ATF3 | activating transcription factor 3 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCL13 | chemokine (C-C motif) ligand 13 |
| CCL21 | chemokine (C-C motif) ligand 21 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CD8A | CD8a molecule |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEL | carboxyl ester lipase |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CPQ | carboxypeptidase Q |
| CTGF | connective tissue growth factor |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DAPK1 | death-associated protein kinase 1 |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DIEXF | digestive organ expansion factor homolog (zebrafish) |
| DLX2 | distal-less homeobox 2 |
| DOCK6 | dedicator of cytokinesis 6 |
| DUOX1 | dual oxidase 1 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| EGR1 | early growth response 1 |
| FAS | Fas cell surface death receptor |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FGL1 | fibrinogen-like 1 |
| FH | fumarate hydratase |
| FSCN1 | fascin actin-bundling protein 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GLS | glutaminase |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPR87 | G protein-coupled receptor 87 |
| HIST1H1T | histone cluster 1, H1t |
| HLA-E | major histocompatibility complex, class I, E |
| HOXB3 | homeobox B3 |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| HTR1A | 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled |
| HYAL1 | hyaluronoglucosaminidase 1 |
| IBSP | integrin-binding sialoprotein |
| IGKV3-20 | immunoglobulin kappa variable 3-20 |
| IL33R | interleukin 33 receptor |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) |
| ITGB8 | integrin, beta 8 |
| KIAA0368 | KIAA0368 |
| KRT17 | keratin 17, type I |
| LIG3 | ligase III, DNA, ATP-dependent |
| LRRC17 | leucine rich repeat containing 17 |
| LTC4S | leukotriene C4 synthase |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MSX1 | msh homeobox 1 |
| MXD4 | MAX dimerization protein 4 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NTF3 | neurotrophin 3 |
| NUP88 | nucleoporin 88kDa |
| OR52A1 | olfactory receptor, family 52, subfamily A, member 1 |
| P2RX2 | purinergic receptor P2X, ligand gated ion channel, 2 |
| PCDHB17P | protocadherin beta 17 pseudogene |
| PLAU | plasminogen activator, urokinase |
| PLAUR | plasminogen activator, urokinase receptor |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| POU6F2 | POU class 6 homeobox 2 |
| PRDM2 | PR domain containing 2, with ZNF domain |
| RAB33A | RAB33A, member RAS oncogene family |
| RGCC | regulator of cell cycle |
| RGS2 | regulator of G-protein signaling 2 |
| RIF1 | replication timing regulatory factor 1 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RNF208 | ring finger protein 208 |
| RPS2 | ribosomal protein S2 |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| SCGB1D1 | secretoglobin, family 1D, member 1 |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SP100 | SP100 nuclear antigen |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| TAAR5 | trace amine associated receptor 5 |
| TEX14 | testis expressed 14 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TWIST1 | twist family bHLH transcription factor 1 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| ZNF407 | zinc finger protein 407 |
| ZNF747 | zinc finger protein 747 |
| Symbol | Name |
|---|---|
| ADNP | activity-dependent neuroprotector homeobox |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ARMCX5 | armadillo repeat containing, X-linked 5 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BANP | BTG3 associated nuclear protein |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C17ORF62 | chromosome 17 open reading frame 62 |
| C5ORF30 | chromosome 5 open reading frame 30 |
| C7ORF49 | chromosome 7 open reading frame 49 |
| CCNF | cyclin F |
| CCNL1 | cyclin L1 |
| CISH | cytokine inducible SH2-containing protein |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| E2F6 | E2F transcription factor 6 |
| E2F8 | E2F transcription factor 8 |
| EFNA1 | ephrin-A1 |
| EFNA4 | ephrin-A4 |
| EGR3 | early growth response 3 |
| ERCC6L | excision repair cross-complementation group 6-like |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FBXL14 | F-box and leucine-rich repeat protein 14 |
| FKBPL | FK506 binding protein like |
| FOXA1 | forkhead box A1 |
| GATA6 | GATA binding protein 6 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HIST1H1B | histone cluster 1, H1b |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H1E | histone cluster 1, H1e |
| HJURP | Holliday junction recognition protein |
| HOXC6 | homeobox C6 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| IER2 | immediate early response 2 |
| IFRD1 | interferon-related developmental regulator 1 |
| IRX5 | iroquois homeobox 5 |
| JMJD1C | jumonji domain containing 1C |
| KIAA0922 | KIAA0922 |
| LOC100272216 | uncharacterized LOC100272216 |
| MED7 | mediator complex subunit 7 |
| METTL18 | methyltransferase like 18 |
| MGA | MGA, MAX dimerization protein |
| MPHOSPH10 | M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) |
| MSL2 | male-specific lethal 2 homolog (Drosophila) |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NDC80 | NDC80 kinetochore complex component |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| PLK2 | polo-like kinase 2 |
| PPP1R3D | protein phosphatase 1, regulatory subunit 3D |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RCL1 | RNA terminal phosphate cyclase-like 1 |
| RLF | rearranged L-myc fusion |
| RPP38 | ribonuclease P/MRP 38kDa subunit |
| SEC24B | SEC24 family member B |
| SERTAD2 | SERTA domain containing 2 |
| SLC38A2 | solute carrier family 38, member 2 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SPATA2L | spermatogenesis associated 2-like |
| STBD1 | starch binding domain 1 |
| TGIF1 | TGFB-induced factor homeobox 1 |
| TOB1 | transducer of ERBB2, 1 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TRAF5 | TNF receptor-associated factor 5 |
| TRIB1 | tribbles pseudokinase 1 |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM13 | tripartite motif containing 13 |
| TRIM32 | tripartite motif containing 32 |
| TRIM52 | tripartite motif containing 52 |
| TTC4 | tetratricopeptide repeat domain 4 |
| XBP1 | X-box binding protein 1 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZBTB24 | zinc finger and BTB domain containing 24 |
| ZC3H4 | zinc finger CCCH-type containing 4 |
| ZNF107 | zinc finger protein 107 |
| ZNF141 | zinc finger protein 141 |
| ZNF165 | zinc finger protein 165 |
| ZNF184 | zinc finger protein 184 |
| ZNF248 | zinc finger protein 248 |
| ZNF253 | zinc finger protein 253 |
| ZNF254 | zinc finger protein 254 |
| ZNF267 | zinc finger protein 267 |
| ZNF282 | zinc finger protein 282 |
| ZNF322P1 | zinc finger protein 322 pseudogene 1 |
| ZNF394 | zinc finger protein 394 |
| ZNF443 | zinc finger protein 443 |
| ZNF552 | zinc finger protein 552 |
| ZNF574 | zinc finger protein 574 |
| ZNF623 | zinc finger protein 623 |
| ZNF84 | zinc finger protein 84 |
| ZSCAN9 | zinc finger and SCAN domain containing 9 |
