| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the mitoxantrone-5354 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ABCD1 | ATP-binding cassette, sub-family D (ALD), member 1 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARL4C | ADP-ribosylation factor-like 4C |
| B4GALT7 | xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C1ORF21 | chromosome 1 open reading frame 21 |
| CCPG1 | cell cycle progression 1 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CFAP70 | cilia and flagella associated protein 70 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
| CLN3 | ceroid-lipofuscinosis, neuronal 3 |
| CNN2 | calponin 2 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DOCK6 | dedicator of cytokinesis 6 |
| EHD2 | EH-domain containing 2 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| EXOC7 | exocyst complex component 7 |
| FBXO31 | F-box protein 31 |
| FLNA | filamin A, alpha |
| FLT1 | fms-related tyrosine kinase 1 |
| FSCN1 | fascin actin-bundling protein 1 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GAL | galanin/GMAP prepropeptide |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| H2AFY2 | H2A histone family, member Y2 |
| HDGFRP3 | hepatoma-derived growth factor, related protein 3 |
| ICAM1 | intercellular adhesion molecule 1 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI35 | interferon-induced protein 35 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFITM1 | interferon induced transmembrane protein 1 |
| ISG15 | ISG15 ubiquitin-like modifier |
| ITGB5 | integrin, beta 5 |
| KIF21B | kinesin family member 21B |
| LAMC2 | laminin, gamma 2 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LMF1 | lipase maturation factor 1 |
| LOXL2 | lysyl oxidase-like 2 |
| MAP4 | microtubule-associated protein 4 |
| MED16 | mediator complex subunit 16 |
| METTL7A | methyltransferase like 7A |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NF2 | neurofibromin 2 (merlin) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| PCDHB3 | protocadherin beta 3 |
| PDCD6 | programmed cell death 6 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PROL1 | proline rich, lacrimal 1 |
| RAD51B | RAD51 paralog B |
| RCN3 | reticulocalbin 3, EF-hand calcium binding domain |
| RPL10 | ribosomal protein L10 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPS3A | ribosomal protein S3A |
| S100A6 | S100 calcium binding protein A6 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SERHL2 | serine hydrolase-like 2 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa |
| SFTPB | surfactant protein B |
| SLC12A8 | solute carrier family 12, member 8 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 |
| SMC1A | structural maintenance of chromosomes 1A |
| SOCS2 | suppressor of cytokine signaling 2 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPRR2B | small proline-rich protein 2B |
| STC1 | stanniocalcin 1 |
| SYNGR1 | synaptogyrin 1 |
| SYT5 | synaptotagmin V |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TBCD | tubulin folding cofactor D |
| TCP10 | t-complex 10 |
| TLE2 | transducin-like enhancer of split 2 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| UPF1 | UPF1 regulator of nonsense transcripts homolog (yeast) |
| VEGFC | vascular endothelial growth factor C |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| ZNF277 | zinc finger protein 277 |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| AEN | apoptosis enhancing nuclease |
| ANKRD49 | ankyrin repeat domain 49 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ARMC7 | armadillo repeat containing 7 |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| CASP8AP2 | caspase 8 associated protein 2 |
| CCNE2 | cyclin E2 |
| CCNL1 | cyclin L1 |
| CDK7 | cyclin-dependent kinase 7 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CHMP7 | charged multivesicular body protein 7 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLDND1 | claudin domain containing 1 |
| CLK1 | CDC-like kinase 1 |
| CLK4 | CDC-like kinase 4 |
| CLP1 | cleavage and polyadenylation factor I subunit 1 |
| CSTF1 | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DOLK | dolichol kinase |
| E2F6 | E2F transcription factor 6 |
| ERCC6L | excision repair cross-complementation group 6-like |
| FANCF | Fanconi anemia, complementation group F |
| FASTKD5 | FAST kinase domains 5 |
| FBXO5 | F-box protein 5 |
| FOXA1 | forkhead box A1 |
| GPATCH1 | G patch domain containing 1 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) |
| HAUS3 | HAUS augmin-like complex, subunit 3 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HIST1H4C | histone cluster 1, H4c |
| HSPA8 | heat shock 70kDa protein 8 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IER3 | immediate early response 3 |
| IER5 | immediate early response 5 |
| JUNB | jun B proto-oncogene |
| KANSL2 | KAT8 regulatory NSL complex subunit 2 |
| KBTBD2 | kelch repeat and BTB (POZ) domain containing 2 |
| KIAA0232 | KIAA0232 |
| KIAA1551 | KIAA1551 |
| KLF10 | Kruppel-like factor 10 |
| LEMD3 | LEM domain containing 3 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MED17 | mediator complex subunit 17 |
| MED7 | mediator complex subunit 7 |
| METTL18 | methyltransferase like 18 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NOTCH2NL | notch 2 N-terminal like |
| OSER1 | oxidative stress responsive serine-rich 1 |
| PCGF1 | polycomb group ring finger 1 |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 |
| PLK2 | polo-like kinase 2 |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| RANBP6 | RAN binding protein 6 |
| RARS | arginyl-tRNA synthetase |
| RBM15 | RNA binding motif protein 15 |
| RBM4B | RNA binding motif protein 4B |
| RHOB | ras homolog family member B |
| RND3 | Rho family GTPase 3 |
| RNF113A | ring finger protein 113A |
| RSBN1 | round spermatid basic protein 1 |
| RSRP1 | arginine/serine-rich protein 1 |
| SERTAD3 | SERTA domain containing 3 |
| SLC38A2 | solute carrier family 38, member 2 |
| SMAD7 | SMAD family member 7 |
| SNRNP35 | small nuclear ribonucleoprotein 35kDa (U11/U12) |
| TAF7 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa |
| TBCC | tubulin folding cofactor C |
| TGIF1 | TGFB-induced factor homeobox 1 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TMEM115 | transmembrane protein 115 |
| TRIB1 | tribbles pseudokinase 1 |
| TRIM13 | tripartite motif containing 13 |
| TRIM32 | tripartite motif containing 32 |
| TRIM52 | tripartite motif containing 52 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TSC22D1 | TSC22 domain family, member 1 |
| TXNIP | thioredoxin interacting protein |
| UBC | ubiquitin C |
| URGCP | upregulator of cell proliferation |
| WDR5B | WD repeat domain 5B |
| ZBED5 | zinc finger, BED-type containing 5 |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZBTB5 | zinc finger and BTB domain containing 5 |
| ZC3H4 | zinc finger CCCH-type containing 4 |
| ZNF107 | zinc finger protein 107 |
| ZNF14 | zinc finger protein 14 |
| ZNF217 | zinc finger protein 217 |
| ZNF267 | zinc finger protein 267 |
| ZNF274 | zinc finger protein 274 |
| ZNF443 | zinc finger protein 443 |
| ZNF587 | zinc finger protein 587 |
| ZNF7 | zinc finger protein 7 |
| ZNF84 | zinc finger protein 84 |
| ZNF85 | zinc finger protein 85 |
