| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the mitoxantrone-6755 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| ACHE | acetylcholinesterase (Yt blood group) |
| ACOXL | acyl-CoA oxidase-like |
| ACTA1 | actin, alpha 1, skeletal muscle |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADPRH | ADP-ribosylarginine hydrolase |
| AGXT | alanine-glyoxylate aminotransferase |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) |
| APOF | apolipoprotein F |
| ARHGEF15 | Rho guanine nucleotide exchange factor (GEF) 15 |
| ARL3 | ADP-ribosylation factor-like 3 |
| ATN1 | atrophin 1 |
| AVPR1A | arginine vasopressin receptor 1A |
| B3GALT2 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 |
| C16ORF70 | chromosome 16 open reading frame 70 |
| C3 | complement component 3 |
| C8ORF4 | chromosome 8 open reading frame 4 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CD244 | CD244 molecule, natural killer cell receptor 2B4 |
| CDHR5 | cadherin-related family member 5 |
| CLEC10A | C-type lectin domain family 10, member A |
| COL10A1 | collagen, type X, alpha 1 |
| CUL3 | cullin 3 |
| DBH | dopamine beta-hydroxylase (dopamine beta-monooxygenase) |
| DCLK2 | doublecortin-like kinase 2 |
| DUX4L8 | double homeobox 4 like 8 |
| EMILIN1 | elastin microfibril interfacer 1 |
| EPS8L1 | EPS8-like 1 |
| FGF18 | fibroblast growth factor 18 |
| FGFR4 | fibroblast growth factor receptor 4 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GPR1 | G protein-coupled receptor 1 |
| GPX5 | glutathione peroxidase 5 |
| GRIK3 | glutamate receptor, ionotropic, kainate 3 |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| HTR2A | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| ILVBL | ilvB (bacterial acetolactate synthase)-like |
| IRF4 | interferon regulatory factor 4 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KCNH1 | potassium channel, voltage gated eag related subfamily H, member 1 |
| KCNK13 | potassium channel, two pore domain subfamily K, member 13 |
| KIAA0087 | KIAA0087 |
| KLKB1 | kallikrein B, plasma (Fletcher factor) 1 |
| KRT6A | keratin 6A, type II |
| LDLR | low density lipoprotein receptor |
| LIG3 | ligase III, DNA, ATP-dependent |
| LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 |
| LMOD1 | leiomodin 1 (smooth muscle) |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MFAP5 | microfibrillar associated protein 5 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MSC | musculin |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle |
| NLRP3 | NLR family, pyrin domain containing 3 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| P2RX1 | purinergic receptor P2X, ligand gated ion channel, 1 |
| PAEP | progestagen-associated endometrial protein |
| PALM | paralemmin |
| PCDHB13 | protocadherin beta 13 |
| PGP | phosphoglycolate phosphatase |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 |
| PRKCA | protein kinase C, alpha |
| PTGIR | prostaglandin I2 (prostacyclin) receptor (IP) |
| RASSF4 | Ras association (RalGDS/AF-6) domain family member 4 |
| RBMY2FP | RNA binding motif protein, Y-linked, family 2, member F pseudogene |
| RHOT2 | ras homolog family member T2 |
| RIC3 | RIC3 acetylcholine receptor chaperone |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RUNDC3A | RUN domain containing 3A |
| S100A5 | S100 calcium binding protein A5 |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC18A2 | solute carrier family 18 (vesicular monoamine transporter), member 2 |
| SOX14 | SRY (sex determining region Y)-box 14 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| TAT | tyrosine aminotransferase |
| TBC1D2 | TBC1 domain family, member 2 |
| TBXA2R | thromboxane A2 receptor |
| TMSB15A | thymosin beta 15a |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TP53 | tumor protein p53 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| WISP3 | WNT1 inducible signaling pathway protein 3 |
| ZBTB7B | zinc finger and BTB domain containing 7B |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| Symbol | Name |
|---|---|
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ADRB2 | adrenoceptor beta 2, surface |
| ALAS1 | 5'-aminolevulinate synthase 1 |
| ANKRD49 | ankyrin repeat domain 49 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein |
| ARID4A | AT rich interactive domain 4A (RBP1-like) |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BANP | BTG3 associated nuclear protein |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| CASP8AP2 | caspase 8 associated protein 2 |
| CCNL1 | cyclin L1 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CENPC | centromere protein C |
| CLK1 | CDC-like kinase 1 |
| CLK4 | CDC-like kinase 4 |
| CLP1 | cleavage and polyadenylation factor I subunit 1 |
| CTGF | connective tissue growth factor |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DOLK | dolichol kinase |
| DUSP6 | dual specificity phosphatase 6 |
| FANCF | Fanconi anemia, complementation group F |
| FASTKD5 | FAST kinase domains 5 |
| FBXO5 | F-box protein 5 |
| FEM1C | fem-1 homolog c (C. elegans) |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GPR87 | G protein-coupled receptor 87 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) |
| HIST1H4C | histone cluster 1, H4c |
| HLX | H2.0-like homeobox |
| HMGA2 | high mobility group AT-hook 2 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IER3 | immediate early response 3 |
| IER5 | immediate early response 5 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| ISL1 | ISL LIM homeobox 1 |
| JMJD1C | jumonji domain containing 1C |
| KANSL2 | KAT8 regulatory NSL complex subunit 2 |
| LIF | leukemia inhibitory factor |
| LOC100272216 | uncharacterized LOC100272216 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| MED7 | mediator complex subunit 7 |
| MTERF1 | mitochondrial transcription termination factor 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| PLK2 | polo-like kinase 2 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| RAB20 | RAB20, member RAS oncogene family |
| RBM4B | RNA binding motif protein 4B |
| RND3 | Rho family GTPase 3 |
| RNF113A | ring finger protein 113A |
| RSBN1 | round spermatid basic protein 1 |
| RSRP1 | arginine/serine-rich protein 1 |
| RUFY2 | RUN and FYVE domain containing 2 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SLC38A2 | solute carrier family 38, member 2 |
| SNAI2 | snail family zinc finger 2 |
| SNIP1 | Smad nuclear interacting protein 1 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SS18L1 | synovial sarcoma translocation gene on chromosome 18-like 1 |
| STBD1 | starch binding domain 1 |
| TBCC | tubulin folding cofactor C |
| TGIF1 | TGFB-induced factor homeobox 1 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TMEM186 | transmembrane protein 186 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRIB1 | tribbles pseudokinase 1 |
| TRIM13 | tripartite motif containing 13 |
| TRIM32 | tripartite motif containing 32 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| WDR5B | WD repeat domain 5B |
| ZBED5 | zinc finger, BED-type containing 5 |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZNF112 | zinc finger protein 112 |
| ZNF14 | zinc finger protein 14 |
| ZNF16 | zinc finger protein 16 |
| ZNF195 | zinc finger protein 195 |
| ZNF217 | zinc finger protein 217 |
| ZNF273 | zinc finger protein 273 |
| ZNF35 | zinc finger protein 35 |
| ZNF443 | zinc finger protein 443 |
| ZNF552 | zinc finger protein 552 |
| ZNF8 | zinc finger protein 8 |
| ZNF84 | zinc finger protein 84 |
| ZNF85 | zinc finger protein 85 |
| ZSCAN16 | zinc finger and SCAN domain containing 16 |
| ZSCAN9 | zinc finger and SCAN domain containing 9 |
