mmp11 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description matrix metallopeptidase 11|Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4320)
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Genes

10 genes co-occuring with the biological term mmp11 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACVR1B activin A receptor, type IB
KRT20 keratin 20, type I
MIR125A microRNA 125a
MIR98 microRNA 98
MMP1 matrix metallopeptidase 1
MMP11 matrix metallopeptidase 11
MMP19 matrix metallopeptidase 19
MMP2 matrix metallopeptidase 2
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7
VEGFA vascular endothelial growth factor A