mode Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

339 genes co-occuring with the biological term mode in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABRA actin binding Rho activating protein
ACP5 acid phosphatase 5, tartrate resistant
ACVR1B activin A receptor, type IB
ADAM10 ADAM metallopeptidase domain 10
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADORA2A adenosine A2a receptor
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
AFP alpha-fetoprotein
AGXT alanine-glyoxylate aminotransferase
ALKBH5 AlkB family member 5, RNA demethylase
ANO1 anoctamin 1, calcium activated chloride channel
APC adenomatous polyposis coli
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARHGAP22 Rho GTPase activating protein 22
ARL2 ADP-ribosylation factor-like 2
ARL2BP ADP-ribosylation factor-like 2 binding protein
ASGR1 asialoglycoprotein receptor 1
ATXN3 ataxin 3
AURKA aurora kinase A
AXIN1 axin 1
BACE1 beta-site APP-cleaving enzyme 1
BCL10 B-cell CLL/lymphoma 10
BDKRB1 bradykinin receptor B1
BGLAP bone gamma-carboxyglutamate (gla) protein
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BST2 bone marrow stromal cell antigen 2
C5 complement component 5
C5AR1 complement component 5a receptor 1
CA2 carbonic anhydrase II
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CALCA calcitonin-related polypeptide alpha
CALR calreticulin
CARD11 caspase recruitment domain family, member 11
CASP4 caspase 4, apoptosis-related cysteine peptidase
CAST calpastatin
CBX5 chromobox homolog 5
CCL2 chemokine (C-C motif) ligand 2
CCL7 chemokine (C-C motif) ligand 7
CCNH cyclin H
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD44 CD44 molecule (Indian blood group)
CDC42 cell division cycle 42
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDK7 cyclin-dependent kinase 7
CDK8 cyclin-dependent kinase 8
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CGA glycoprotein hormones, alpha polypeptide
CHD7 chromodomain helicase DNA binding protein 7
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHRM1 cholinergic receptor, muscarinic 1
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHUK conserved helix-loop-helix ubiquitous kinase
CLGN calmegin
COL11A1 collagen, type XI, alpha 1
COL18A1 collagen, type XVIII, alpha 1
COL7A1 collagen, type VII, alpha 1
COMP cartilage oligomeric matrix protein
COMT catechol-O-methyltransferase
CPB2 carboxypeptidase B2 (plasma)
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRH corticotropin releasing hormone
CTSL cathepsin L
CUL3 cullin 3
CWC22 CWC22 spliceosome-associated protein
CXCL14 chemokine (C-X-C motif) ligand 14
CXCR2 chemokine (C-X-C motif) receptor 2
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
DBF4 DBF4 zinc finger
DCC DCC netrin 1 receptor
DDR2 discoidin domain receptor tyrosine kinase 2
DGKZ diacylglycerol kinase, zeta
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DLG1 discs, large homolog 1 (Drosophila)
DNM1L dynamin 1-like
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DOCK2 dedicator of cytokinesis 2
DOCK9 dedicator of cytokinesis 9
DOT1L DOT1-like histone H3K79 methyltransferase
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
DRD2 dopamine receptor D2
DRD4 dopamine receptor D4
DUSP10 dual specificity phosphatase 10
ECI1 enoyl-CoA delta isomerase 1
EDN1 endothelin 1
EFNB2 ephrin-B2
EGFR epidermal growth factor receptor
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF4A3 eukaryotic translation initiation factor 4A3
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
ELANE elastase, neutrophil expressed
ELAVL1 ELAV like RNA binding protein 1
ELAVL4 ELAV like neuron-specific RNA binding protein 4
ELK1 ELK1, member of ETS oncogene family
EPHA2 EPH receptor A2
EPHB4 EPH receptor B4
ESR1 estrogen receptor 1
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FADD Fas (TNFRSF6)-associated via death domain
FAS Fas cell surface death receptor
FASN fatty acid synthase
FBXO32 F-box protein 32
FERMT2 fermitin family member 2
FFAR4 free fatty acid receptor 4
FGF8 fibroblast growth factor 8 (androgen-induced)
FGFR2 fibroblast growth factor receptor 2
FKBP5 FK506 binding protein 5
FLT3 fms-related tyrosine kinase 3
FMR1 fragile X mental retardation 1
FNTA farnesyltransferase, CAAX box, alpha
FOXO1 forkhead box O1
GABARAP GABA(A) receptor-associated protein
GABARAPL2 GABA(A) receptor-associated protein-like 2
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GATA1 GATA binding protein 1 (globin transcription factor 1)
GDAP1 ganglioside induced differentiation associated protein 1
GIP gastric inhibitory polypeptide
GIPR gastric inhibitory polypeptide receptor
GJA8 gap junction protein, alpha 8, 50kDa
GJB2 gap junction protein, beta 2, 26kDa
GJB3 gap junction protein, beta 3, 31kDa
GLCE glucuronic acid epimerase
GLTP glycolipid transfer protein
GM2A GM2 ganglioside activator
GNAS GNAS complex locus
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GOPC golgi-associated PDZ and coiled-coil motif containing
GP6 glycoprotein VI (platelet)
GRB2 growth factor receptor-bound protein 2
GTF2B general transcription factor IIB
GUCY2F guanylate cyclase 2F, retinal
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HBA2 hemoglobin, alpha 2
HBEGF heparin-binding EGF-like growth factor
HCK HCK proto-oncogene, Src family tyrosine kinase
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST1H1B histone cluster 1, H1b
HLA-A major histocompatibility complex, class I, A
HLA-G major histocompatibility complex, class I, G
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGN1 high mobility group nucleosome binding domain 1
HMGN2 high mobility group nucleosomal binding domain 2
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HPSE heparanase
HTT huntingtin
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IGF1 insulin-like growth factor 1 (somatomedin C)
IL10 interleukin 10
IL17D interleukin 17D
IL24 interleukin 24
IL2RA interleukin 2 receptor, alpha
IL5 interleukin 5
INPPL1 inositol polyphosphate phosphatase-like 1
INS insulin
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA6 integrin, alpha 6
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KANK1 KN motif and ankyrin repeat domains 1
KATNA1 katanin p60 (ATPase containing) subunit A 1
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KLHL22 kelch-like family member 22
KLK3 kallikrein-related peptidase 3
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LDLR low density lipoprotein receptor
LEP leptin
LGALS1 lectin, galactoside-binding, soluble, 1
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
LRP1 low density lipoprotein receptor-related protein 1
LRP2 low density lipoprotein receptor-related protein 2
LYNX1 Ly6/neurotoxin 1
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPT microtubule-associated protein tau
MET MET proto-oncogene, receptor tyrosine kinase
MGMT O-6-methylguanine-DNA methyltransferase
MIR122 microRNA 122
MIR146A microRNA 146a
MIR17HG miR-17-92 cluster host gene
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MNAT1 MNAT CDK-activating kinase assembly factor 1
MORF4L1 mortality factor 4 like 1
MPO myeloperoxidase
MPP1 membrane protein, palmitoylated 1, 55kDa
MR1 major histocompatibility complex, class I-related
MRPL41 mitochondrial ribosomal protein L41
MSTN myostatin
MTO1 mitochondrial tRNA translation optimization 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH9 myosin, heavy chain 9, non-muscle
MYOCD myocardin
NBN nibrin
NES nestin
NLGN1 neuroligin 1
NOTCH2 notch 2
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NSF N-ethylmaleimide-sensitive factor
OGG1 8-oxoguanine DNA glycosylase
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OSBPL8 oxysterol binding protein-like 8
PARN poly(A)-specific ribonuclease
PARP1 poly (ADP-ribose) polymerase 1
PCNA proliferating cell nuclear antigen
PDGFA platelet-derived growth factor alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PIEZO1 piezo-type mechanosensitive ion channel component 1
PILRA paired immunoglobin-like type 2 receptor alpha
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PINK1 PTEN induced putative kinase 1
PLK1 polo-like kinase 1
POLB polymerase (DNA directed), beta
POLI polymerase (DNA directed) iota
POU6F1 POU class 6 homeobox 1
PPARA peroxisome proliferator-activated receptor alpha
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PRNP prion protein
PRSS1 protease, serine, 1 (trypsin 1)
PRTFDC1 phosphoribosyl transferase domain containing 1
PTGR2 prostaglandin reductase 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTX3 pentraxin 3, long
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RARA retinoic acid receptor, alpha
RBM25 RNA binding motif protein 25
RBP7 retinol binding protein 7, cellular
RECQL5 RecQ protein-like 5
RFX1 regulatory factor X, 1 (influences HLA class II expression)
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF111 ring finger protein 111
RTN3 reticulon 3
S100A4 S100 calcium binding protein A4
SALL1 spalt-like transcription factor 1
SATB1 SATB homeobox 1
SCN4A sodium channel, voltage gated, type IV alpha subunit
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SF3B1 splicing factor 3b, subunit 1, 155kDa
SIGLEC8 sialic acid binding Ig-like lectin 8
SIRT1 sirtuin 1
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SMAD7 SMAD family member 7
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNW1 SNW domain containing 1
SOCS7 suppressor of cytokine signaling 7
SOD2 superoxide dismutase 2, mitochondrial
SSB Sjogren syndrome antigen B (autoantigen La)
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAR steroidogenic acute regulatory protein
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STIM2 stromal interaction molecule 2
TAC3 tachykinin 3
TBXA2R thromboxane A2 receptor
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR1 transforming growth factor, beta receptor 1
THRA thyroid hormone receptor, alpha
THRB thyroid hormone receptor, beta
TKT transketolase
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TOPBP1 topoisomerase (DNA) II binding protein 1
TP53 tumor protein p53
TPH2 tryptophan hydroxylase 2
TPM2 tropomyosin 2 (beta)
TPO thyroid peroxidase
TRA T cell receptor alpha locus
TRB T cell receptor beta locus
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TYRP1 tyrosinase-related protein 1
UBC ubiquitin C
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast)
USO1 USO1 vesicle transport factor
VAV1 vav 1 guanine nucleotide exchange factor
VDAC1 voltage-dependent anion channel 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
VTN vitronectin
VWF von Willebrand factor
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WT1 Wilms tumor 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YTHDC1 YTH domain containing 1
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF148 zinc finger protein 148
ZP1 zona pellucida glycoprotein 1 (sperm receptor)