modulation of chemical synaptic transmission Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency or rate of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. (Gene Ontology, GO_0050804)
External Link http://amigo.geneontology.org/amigo/term/GO_0050804
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Genes

124 genes participating in the modulation of chemical synaptic transmission biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ABR active BCR-related
ADIPOQ adiponectin, C1Q and collagen domain containing
AGER advanced glycosylation end product-specific receptor
AKAP9 A kinase (PRKA) anchor protein 9
APP amyloid beta (A4) precursor protein
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
BAIAP3 BAI1-associated protein 3
BCR breakpoint cluster region
BEGAIN brain-enriched guanylate kinase-associated
BTBD9 BTB (POZ) domain containing 9
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CACNG5 calcium channel, voltage-dependent, gamma subunit 5
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK5 cyclin-dependent kinase 5
CDKL5 cyclin-dependent kinase-like 5
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CLN3 ceroid-lipofuscinosis, neuronal 3
CLSTN1 calsyntenin 1
CLSTN2 calsyntenin 2
CLSTN3 calsyntenin 3
CNTNAP4 contactin associated protein-like 4
CPLX1 complexin 1
CPLX2 complexin 2
CPLX3 complexin 3
CPLX4 complexin 4
CX3CR1 chemokine (C-X3-C motif) receptor 1
DGKI diacylglycerol kinase, iota
DGKZ diacylglycerol kinase, zeta
DLG4 discs, large homolog 4 (Drosophila)
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DLGAP2 discs, large (Drosophila) homolog-associated protein 2
DLGAP3 discs, large (Drosophila) homolog-associated protein 3
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DRD2 dopamine receptor D2
DYSF dysferlin
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
FER1L4 fer-1-like family member 4, pseudogene (functional)
FER1L5 fer-1-like family member 5
FMR1 fragile X mental retardation 1
FXR1 fragile X mental retardation, autosomal homolog 1
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRIA4 glutamate receptor, ionotropic, AMPA 4
GRID1 glutamate receptor, ionotropic, delta 1
GRID2 glutamate receptor, ionotropic, delta 2
GRIK1 glutamate receptor, ionotropic, kainate 1
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIK3 glutamate receptor, ionotropic, kainate 3
GRIK4 glutamate receptor, ionotropic, kainate 4
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
GRM1 glutamate receptor, metabotropic 1
GRM2 glutamate receptor, metabotropic 2
GRM3 glutamate receptor, metabotropic 3
GRM4 glutamate receptor, metabotropic 4
GRM5 glutamate receptor, metabotropic 5
GRM6 glutamate receptor, metabotropic 6
GRM7 glutamate receptor, metabotropic 7
GRM8 glutamate receptor, metabotropic 8
GSK3B glycogen synthase kinase 3 beta
HCRT hypocretin (orexin) neuropeptide precursor
HOMER1 homer scaffolding protein 1
IL1B interleukin 1, beta
IQSEC2 IQ motif and Sec7 domain 2
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KCTD13 potassium channel tetramerization domain containing 13
LGI1 leucine-rich, glioma inactivated 1
LPPR4 lipid phosphate phosphatase-related protein type 4
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRC4 leucine rich repeat containing 4
LRRC4C leucine rich repeat containing 4C
LRRK2 leucine-rich repeat kinase 2
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MCTP1 multiple C2 domains, transmembrane 1
MCTP2 multiple C2 domains, transmembrane 2
MEF2C myocyte enhancer factor 2C
MYOF myoferlin
NLGN1 neuroligin 1
NLGN2 neuroligin 2
NLGN3 neuroligin 3
NLGN4X neuroligin 4, X-linked
NLGN4Y neuroligin 4, Y-linked
NMU neuromedin U
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NPAS4 neuronal PAS domain protein 4
NPTX1 neuronal pentraxin I
NPTX2 neuronal pentraxin II
NPTXR neuronal pentraxin receptor
NRG3 neuregulin 3
OPHN1 oligophrenin 1
OTOF otoferlin
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PTEN phosphatase and tensin homolog
PXK PX domain containing serine/threonine kinase
RELN reelin
RIMS1 regulating synaptic membrane exocytosis 1
RIMS2 regulating synaptic membrane exocytosis 2
RIMS3 regulating synaptic membrane exocytosis 3
RIMS4 regulating synaptic membrane exocytosis 4
RNF167 ring finger protein 167
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC38A1 solute carrier family 38, member 1
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3
SNCAIP synuclein, alpha interacting protein
SYN1 synapsin I
SYN3 synapsin III
SYT1 synaptotagmin I
TMEM108 transmembrane protein 108
TNF tumor necrosis factor
TPRG1L tumor protein p63 regulated 1-like
TRIO trio Rho guanine nucleotide exchange factor
UNC13A unc-13 homolog A (C. elegans)
USP46 ubiquitin specific peptidase 46