modulators Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

174 genes co-occuring with the biological term modulators in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADAM9 ADAM metallopeptidase domain 9
ADORA3 adenosine A3 receptor
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
APOA1 apolipoprotein A-I
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
BACE1 beta-site APP-cleaving enzyme 1
BDNF brain-derived neurotrophic factor
BEST1 bestrophin 1
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMP2 bone morphogenetic protein 2
BRINP1 bone morphogenetic protein/retinoic acid inducible neural-specific 1
CAPN3 calpain 3, (p94)
CARTPT CART prepropeptide
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CD274 CD274 molecule
CERS1 ceramide synthase 1
CETP cholesteryl ester transfer protein, plasma
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHGA chromogranin A
CHRM2 cholinergic receptor, muscarinic 2
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CLCA1 chloride channel accessory 1
CLCA4 chloride channel accessory 4
CLN5 ceroid-lipofuscinosis, neuronal 5
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CNR1 cannabinoid receptor 1 (brain)
COMT catechol-O-methyltransferase
CPT2 carnitine palmitoyltransferase 2
CRMP1 collapsin response mediator protein 1
CTSL cathepsin L
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DPYD dihydropyrimidine dehydrogenase
E2F1 E2F transcription factor 1
EDN1 endothelin 1
ELANE elastase, neutrophil expressed
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FAS Fas cell surface death receptor
FGF23 fibroblast growth factor 23
FHL2 four and a half LIM domains 2
FOXO1 forkhead box O1
FXYD4 FXYD domain containing ion transport regulator 4
FZD1 frizzled class receptor 1
FZD5 frizzled class receptor 5
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GH1 growth hormone 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLRA1 glycine receptor, alpha 1
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GPR119 G protein-coupled receptor 119
GRN granulin
GSK3B glycogen synthase kinase 3 beta
HSF1 heat shock transcription factor 1
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
ICAM1 intercellular adhesion molecule 1
IDO1 indoleamine 2,3-dioxygenase 1
IFI35 interferon-induced protein 35
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFBP5 insulin-like growth factor binding protein 5
IL1RAP interleukin 1 receptor accessory protein
IL6 interleukin 6
ILK integrin-linked kinase
ING4 inhibitor of growth family, member 4
ING5 inhibitor of growth family, member 5
INHBA inhibin, beta A
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KIF2C kinesin family member 2C
KPNA1 karyopherin alpha 1 (importin alpha 5)
LCAT lecithin-cholesterol acyltransferase
LCMT1 leucine carboxyl methyltransferase 1
LOXL2 lysyl oxidase-like 2
MAPK14 mitogen-activated protein kinase 14
MCOLN1 mucolipin 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MIR27A microRNA 27a
MIR27B microRNA 27b
MIR328 microRNA 328
MIR491 microRNA 491
MMP12 matrix metallopeptidase 12
MMP9 matrix metallopeptidase 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO18A myosin XVIIIA
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NELFA negative elongation factor complex member A
NELFB negative elongation factor complex member B
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NMI N-myc (and STAT) interactor
NPY2R neuropeptide Y receptor Y2
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OPRM1 opioid receptor, mu 1
ORMDL1 ORMDL sphingolipid biosynthesis regulator 1
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
OTX1 orthodenticle homeobox 1
OTX2 orthodenticle homeobox 2
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PDCD1 programmed cell death 1
PDGFC platelet derived growth factor C
PIAS4 protein inhibitor of activated STAT, 4
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD2 phospholipase D2
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPME1 protein phosphatase methylesterase 1
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PRL prolactin
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RFX1 regulatory factor X, 1 (influences HLA class II expression)
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RFX3 regulatory factor X, 3 (influences HLA class II expression)
RHOJ ras homolog family member J
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK3 receptor-interacting serine-threonine kinase 3
RPS19BP1 ribosomal protein S19 binding protein 1
RXRA retinoid X receptor, alpha
SAFB scaffold attachment factor B
SCN10A sodium channel, voltage gated, type X alpha subunit
SCO2 SCO2 cytochrome c oxidase assembly protein
SGK1 serum/glucocorticoid regulated kinase 1
SIRT3 sirtuin 3
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
TAS1R2 taste receptor, type 1, member 2
TAS1R3 taste receptor, type 1, member 3
TGFB1 transforming growth factor, beta 1
THRA thyroid hormone receptor, alpha
THRB thyroid hormone receptor, beta
TIGAR TP53 induced glycolysis regulatory phosphatase
TIPRL TOR signaling pathway regulator
TNF tumor necrosis factor
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TRPV1 transient receptor potential cation channel, subfamily V, member 1
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
WIF1 WNT inhibitory factor 1
WISP1 WNT1 inducible signaling pathway protein 1
WNT7A wingless-type MMTV integration site family, member 7A
WWTR1 WW domain containing transcription regulator 1
ZFP36 ZFP36 ring finger protein