module Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

257 genes co-occuring with the biological term module in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACTG1 actin gamma 1
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAM17 ADAM metallopeptidase domain 17
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANAPC11 anaphase promoting complex subunit 11
ANAPC2 anaphase promoting complex subunit 2
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APTR Alu-mediated CDKN1A/p21 transcriptional regulator (non-protein coding)
AR androgen receptor
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
ATRX alpha thalassemia/mental retardation syndrome X-linked
B9D1 B9 protein domain 1
BCAM basal cell adhesion molecule (Lutheran blood group)
BDNF brain-derived neurotrophic factor
BIRC2 baculoviral IAP repeat containing 2
BIRC5 baculoviral IAP repeat containing 5
BRCA2 breast cancer 2, early onset
BRPF1 bromodomain and PHD finger containing, 1
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QC complement component 1, q subcomponent, C chain
C1R complement component 1, r subcomponent
C3 complement component 3
C5 complement component 5
C7 complement component 7
C8A complement component 8, alpha polypeptide
C8B complement component 8, beta polypeptide
C8G complement component 8, gamma polypeptide
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CARM1 coactivator-associated arginine methyltransferase 1
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBS cystathionine-beta-synthase
CCND1 cyclin D1
CDC37 cell division cycle 37
CDCA8 cell division cycle associated 8
CDK8 cyclin-dependent kinase 8
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFH complement factor H
CFL1 cofilin 1 (non-muscle)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHEK1 checkpoint kinase 1
CHIA chitinase, acidic
CLP1 cleavage and polyadenylation factor I subunit 1
CLSPN claspin
COL18A1 collagen, type XVIII, alpha 1
COL2A1 collagen, type II, alpha 1
COPG1 coatomer protein complex, subunit gamma 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CTGF connective tissue growth factor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXADR coxsackie virus and adenovirus receptor
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DAPK1 death-associated protein kinase 1
DIAPH3 diaphanous-related formin 3
DLG1 discs, large homolog 1 (Drosophila)
DNM1 dynamin 1
DOK3 docking protein 3
DOT1L DOT1-like histone H3K79 methyltransferase
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2)
DYNLL1 dynein, light chain, LC8-type 1
E2F1 E2F transcription factor 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ENO1 enolase 1, (alpha)
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERBB4 erb-b2 receptor tyrosine kinase 4
ERRFI1 ERBB receptor feedback inhibitor 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FCAR Fc fragment of IgA receptor
FMR1 fragile X mental retardation 1
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL1 FOS-like antigen 1
FOXM1 forkhead box M1
FZD1 frizzled class receptor 1
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1
GEMIN5 gem (nuclear organelle) associated protein 5
GHR growth hormone receptor
GIP gastric inhibitory polypeptide
GLS glutaminase
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GRB2 growth factor receptor-bound protein 2
GSN gelsolin
GSTP1 glutathione S-transferase pi 1
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIP1 huntingtin interacting protein 1
HIP1R huntingtin interacting protein 1 related
HNF4A hepatocyte nuclear factor 4, alpha
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
IAPP islet amyloid polypeptide
IFT74 intraflagellar transport 74
IFT81 intraflagellar transport 81
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2R insulin-like growth factor 2 receptor
IL1A interleukin 1, alpha
IL1RAP interleukin 1 receptor accessory protein
IL6R interleukin 6 receptor
ILK integrin-linked kinase
INCENP inner centromere protein antigens 135/155kDa
INVS inversin
IRAK1 interleukin-1 receptor-associated kinase 1
ITGA8 integrin, alpha 8
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAG1 jagged 1
JAK2 Janus kinase 2
KAT2A K(lysine) acetyltransferase 2A
KAT2B K(lysine) acetyltransferase 2B
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KDM1A lysine (K)-specific demethylase 1A
KDM4A lysine (K)-specific demethylase 4A
KIF13B kinesin family member 13B
LAMA3 laminin, alpha 3
LAMA4 laminin, alpha 4
LDB2 LIM domain binding 2
LDLR low density lipoprotein receptor
LIFR leukemia inhibitory factor receptor alpha
LINGO1 leucine rich repeat and Ig domain containing 1
LRP6 low density lipoprotein receptor-related protein 6
LYN LYN proto-oncogene, Src family tyrosine kinase
MAN1B1 mannosidase, alpha, class 1B, member 1
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED18 mediator complex subunit 18
MIR378A microRNA 378a
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MORF4L1 mortality factor 4 like 1
MRPL13 mitochondrial ribosomal protein L13
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MUC1 mucin 1, cell surface associated
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO18A myosin XVIIIA
NCF1 neutrophil cytosolic factor 1
ND1
NEK6 NIMA-related kinase 6
NEK8 NIMA-related kinase 8
NEK9 NIMA-related kinase 9
NF1 neurofibromin 1
NGLY1 N-glycanase 1
NPHP3 nephronophthisis 3 (adolescent)
NR2C2 nuclear receptor subfamily 2, group C, member 2
NUP107 nucleoporin 107kDa
NUP133 nucleoporin 133kDa
OCRL oculocerebrorenal syndrome of Lowe
ORC1 origin recognition complex, subunit 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PCOLCE procollagen C-endopeptidase enhancer
PDE4A phosphodiesterase 4A, cAMP-specific
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLK1 polo-like kinase 1
PLK3 polo-like kinase 3
PLXNC1 plexin C1
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
PRKD1 protein kinase D1
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
PSEN1 presenilin 1
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PXN paxillin
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD23B RAD23 homolog B (S. cerevisiae)
RAD51 RAD51 recombinase
RAN RAN, member RAS oncogene family
RAP1A RAP1A, member of RAS oncogene family
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RECQL5 RecQ protein-like 5
RHOA ras homolog family member A
RNF185 ring finger protein 185
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RRAS related RAS viral (r-ras) oncogene homolog
RXFP1 relaxin/insulin-like family peptide receptor 1
RXFP2 relaxin/insulin-like family peptide receptor 2
SCN4A sodium channel, voltage gated, type IV alpha subunit
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SH3PXD2A SH3 and PX domains 2A
SHOC2 soc-2 suppressor of clear homolog (C. elegans)
SIRT1 sirtuin 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNAI1 snail family zinc finger 1
SOS1 son of sevenless homolog 1 (Drosophila)
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SS18 synovial sarcoma translocation, chromosome 18
STIM2 stromal interaction molecule 2
STK17B serine/threonine kinase 17b
SYK spleen tyrosine kinase
TAS1R2 taste receptor, type 1, member 2
TAS1R3 taste receptor, type 1, member 3
TBRG1 transforming growth factor beta regulator 1
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
THBS1 thrombospondin 1
THBS2 thrombospondin 2
TIAM1 T-cell lymphoma invasion and metastasis 1
TJP1 tight junction protein 1
TLN1 talin 1
TLN2 talin 2
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TOB2 transducer of ERBB2, 2
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TP63 tumor protein p63
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TTK TTK protein kinase
TYK2 tyrosine kinase 2
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UHRF1 ubiquitin-like with PHD and ring finger domains 1
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast)
USP22 ubiquitin specific peptidase 22
VCP valosin containing protein
VDAC3 voltage-dependent anion channel 3
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VLDLR very low density lipoprotein receptor
VRK1 vaccinia related kinase 1
WIPF1 WAS/WASL interacting protein family, member 1
WWOX WW domain containing oxidoreductase
XCL1 chemokine (C motif) ligand 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZEB1 zinc finger E-box binding homeobox 1
ZNF197 zinc finger protein 197
ZP1 zona pellucida glycoprotein 1 (sperm receptor)