molindone-4199 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the molindone-4199 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM28 ADAM metallopeptidase domain 28
AIM1L absent in melanoma 1-like
AKAP8L A kinase (PRKA) anchor protein 8-like
ALOXE3 arachidonate lipoxygenase 3
BAGE B melanoma antigen
BATF basic leucine zipper transcription factor, ATF-like
BEX1 brain expressed, X-linked 1
BIRC7 baculoviral IAP repeat containing 7
C11ORF63 chromosome 11 open reading frame 63
CAMKV CaM kinase-like vesicle-associated
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCNG2 cyclin G2
CCR7 chemokine (C-C motif) receptor 7
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CLCA2 chloride channel accessory 2
CLIC5 chloride intracellular channel 5
CLPS colipase, pancreatic
CNTNAP2 contactin associated protein-like 2
COL17A1 collagen, type XVII, alpha 1
COL1A2 collagen, type I, alpha 2
CSPG4 chondroitin sulfate proteoglycan 4
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
DIAPH2-AS1 DIAPH2 antisense RNA 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DTNA dystrobrevin, alpha
EFNB3 ephrin-B3
EFR3B EFR3 homolog B (S. cerevisiae)
EMP1 epithelial membrane protein 1
ETV1 ets variant 1
FAM134B family with sequence similarity 134, member B
FAS Fas cell surface death receptor
FLJ11292
GAB1 GRB2-associated binding protein 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GAL3ST4 galactose-3-O-sulfotransferase 4
GJA8 gap junction protein, alpha 8, 50kDa
GOLGA8A golgin A8 family, member A
GPR27 G protein-coupled receptor 27
GSPT1 G1 to S phase transition 1
HDAC6 histone deacetylase 6
HIPK3 homeodomain interacting protein kinase 3
HNF4A hepatocyte nuclear factor 4, alpha
HSF2BP heat shock transcription factor 2 binding protein
IFITM1 interferon induced transmembrane protein 1
KCNIP1 Kv channel interacting protein 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIF1C kinesin family member 1C
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLF12 Kruppel-like factor 12
LAT2 linker for activation of T cells family, member 2
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LGALS8 lectin, galactoside-binding, soluble, 8
LPIN1 lipin 1
LUM lumican
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MMP9 matrix metallopeptidase 9
MORC1 MORC family CW-type zinc finger 1
MTRF1L mitochondrial translational release factor 1-like
MUC7 mucin 7, secreted
NCF4 neutrophil cytosolic factor 4, 40kDa
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NTNG1 netrin G1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OAZ3 ornithine decarboxylase antizyme 3
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OSR2 odd-skipped related transciption factor 2
PCDHA5 protocadherin alpha 5
PDLIM5 PDZ and LIM domain 5
PGPEP1 pyroglutamyl-peptidase I
PKNOX2 PBX/knotted 1 homeobox 2
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PPARD peroxisome proliferator-activated receptor delta
PRR15L proline rich 15-like
PTPRG protein tyrosine phosphatase, receptor type, G
PYGO1 pygopus family PHD finger 1
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RNF32 ring finger protein 32
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SETDB1 SET domain, bifurcated 1
SFRP4 secreted frizzled-related protein 4
SH2D2A SH2 domain containing 2A
SMC1A structural maintenance of chromosomes 1A
SOAT1 sterol O-acyltransferase 1
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
SYNGR3 synaptogyrin 3
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFR2 transferrin receptor 2
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TPTE transmembrane phosphatase with tensin homology
TTC30A tetratricopeptide repeat domain 30A
VWA5A von Willebrand factor A domain containing 5A
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF214 zinc finger protein 214
ZNF280B zinc finger protein 280B
ZNF467 zinc finger protein 467

decreased expression

Symbol Name
ACE angiotensin I converting enzyme
ALPK1 alpha-kinase 1
ANG angiogenin, ribonuclease, RNase A family, 5
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARMC6 armadillo repeat containing 6
BTBD2 BTB (POZ) domain containing 2
C14ORF105 chromosome 14 open reading frame 105
C1RL complement component 1, r subcomponent-like
C22ORF46 chromosome 22 open reading frame 46
C8A complement component 8, alpha polypeptide
CAMKMT calmodulin-lysine N-methyltransferase
CASS4 Cas scaffolding protein family member 4
CBX8 chromobox homolog 8
CEMP1 cementum protein 1
CLEC16A C-type lectin domain family 16, member A
CLTCL1 clathrin, heavy chain-like 1
CNN1 calponin 1, basic, smooth muscle
CTSF cathepsin F
EFNA3 ephrin-A3
FBXL2 F-box and leucine-rich repeat protein 2
FKBP5 FK506 binding protein 5
FOXA1 forkhead box A1
FRMPD1 FERM and PDZ domain containing 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GLS2 glutaminase 2 (liver, mitochondrial)
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
GRM4 glutamate receptor, metabotropic 4
GSTA3 glutathione S-transferase alpha 3
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HOXA6 homeobox A6
IFT140 intraflagellar transport 140
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
ITGA10 integrin, alpha 10
ITGB7 integrin, beta 7
KANSL3 KAT8 regulatory NSL complex subunit 3
KIAA0319L KIAA0319-like
LIME1 Lck interacting transmembrane adaptor 1
LMCD1 LIM and cysteine-rich domains 1
LOC100287590 uncharacterized LOC100287590
LRP3 low density lipoprotein receptor-related protein 3
LRRC61 leucine rich repeat containing 61
LRRK1 leucine-rich repeat kinase 1
LY6E lymphocyte antigen 6 complex, locus E
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MFGE8 milk fat globule-EGF factor 8 protein
MGP matrix Gla protein
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MMP2 matrix metallopeptidase 2
MRAS muscle RAS oncogene homolog
MRPS18C mitochondrial ribosomal protein S18C
MTSS1L metastasis suppressor 1-like
MYOZ3 myozenin 3
NAT6 N-acetyltransferase 6 (GCN5-related)
NOL12 nucleolar protein 12
NRSN2 neurensin 2
NT5DC3 5'-nucleotidase domain containing 3
NT5M 5',3'-nucleotidase, mitochondrial
NTSR1 neurotensin receptor 1 (high affinity)
OLFML2A olfactomedin-like 2A
PDE12 phosphodiesterase 12
PLBD1 phospholipase B domain containing 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
RAD54L2 RAD54-like 2 (S. cerevisiae)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
SAMD9 sterile alpha motif domain containing 9
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNPH syntaphilin
SOX21 SRY (sex determining region Y)-box 21
SPATA1 spermatogenesis associated 1
SPTBN2 spectrin, beta, non-erythrocytic 2
SSBP3 single stranded DNA binding protein 3
STEAP4 STEAP family member 4
STX5 syntaxin 5
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TBC1D17 TBC1 domain family, member 17
TLN1 talin 1
TMEM132A transmembrane protein 132A
TMPRSS4 transmembrane protease, serine 4
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TSPAN2 tetraspanin 2
TUBB2B tubulin, beta 2B class IIb
URM1 ubiquitin related modifier 1
VEGFB vascular endothelial growth factor B
XAB2 XPA binding protein 2
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF276 zinc finger protein 276
ZNF428 zinc finger protein 428
ZNF528 zinc finger protein 528
ZNF767P zinc finger family member 767, pseudogene