molsidomine-1711 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the molsidomine-1711 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ABHD3 abhydrolase domain containing 3
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
AMBRA1 autophagy/beclin-1 regulator 1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APP amyloid beta (A4) precursor protein
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASMTL acetylserotonin O-methyltransferase-like
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTBD3 BTB (POZ) domain containing 3
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CCDC186 coiled-coil domain containing 186
CCDC64 coiled-coil domain containing 64
CD2BP2 CD2 (cytoplasmic tail) binding protein 2
CDC42 cell division cycle 42
CHAF1B chromatin assembly factor 1, subunit B (p60)
CLEC4M C-type lectin domain family 4, member M
CLIP1 CAP-GLY domain containing linker protein 1
CORO2A coronin, actin binding protein, 2A
CYB561 cytochrome b561
DGCR8 DGCR8 microprocessor complex subunit
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8
DUSP13 dual specificity phosphatase 13
EFNB3 ephrin-B3
EMP1 epithelial membrane protein 1
ERP44 endoplasmic reticulum protein 44
EVI5 ecotropic viral integration site 5
FAM76A family with sequence similarity 76, member A
FANCF Fanconi anemia, complementation group F
FASTK Fas-activated serine/threonine kinase
FSCN1 fascin actin-bundling protein 1
GALNS galactosamine (N-acetyl)-6-sulfatase
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GSR glutathione reductase
GTF2I general transcription factor IIi
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGB7 integrin, beta 7
KPTN kaptin (actin binding protein)
KRIT1 KRIT1, ankyrin repeat containing
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LIMS2 LIM and senescent cell antigen-like domains 2
LPAR1 lysophosphatidic acid receptor 1
MANSC1 MANSC domain containing 1
MEF2D myocyte enhancer factor 2D
MID2 midline 2
MORC2 MORC family CW-type zinc finger 2
MSH3 mutS homolog 3
MSH6 mutS homolog 6
MXRA8 matrix-remodelling associated 8
NOTCH2 notch 2
NRSN2 neurensin 2
NUP210 nucleoporin 210kDa
OCRL oculocerebrorenal syndrome of Lowe
PADI1 peptidyl arginine deiminase, type I
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PBX2 pre-B-cell leukemia homeobox 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCNX pecanex homolog (Drosophila)
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PEX7 peroxisomal biogenesis factor 7
PGC progastricsin (pepsinogen C)
PHF7 PHD finger protein 7
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PITPNA phosphatidylinositol transfer protein, alpha
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRDM11 PR domain containing 11
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRRC2B proline-rich coiled-coil 2B
PTCRA pre T-cell antigen receptor alpha
PTGES prostaglandin E synthase
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RHOT2 ras homolog family member T2
RNASE3 ribonuclease, RNase A family, 3
RORC RAR-related orphan receptor C
S1PR4 sphingosine-1-phosphate receptor 4
SDC2 syndecan 2
SEC31B SEC31 homolog B (S. cerevisiae)
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SFTPB surfactant protein B
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SOD3 superoxide dismutase 3, extracellular
SPN sialophorin
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STRN striatin, calmodulin binding protein
TBXA2R thromboxane A2 receptor
TCTN1 tectonic family member 1
USB1 U6 snRNA biogenesis 1
USP34 ubiquitin specific peptidase 34
VCX2 variable charge, X-linked 2
WDR82 WD repeat domain 82
XPO4 exportin 4
YIPF2 Yip1 domain family, member 2
ZC3H7B zinc finger CCCH-type containing 7B
ZEB2 zinc finger E-box binding homeobox 2
ZNF771 zinc finger protein 771
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARMCX5 armadillo repeat containing, X-linked 5
ASB13 ankyrin repeat and SOCS box containing 13
BBC3 BCL2 binding component 3
BCL7C B-cell CLL/lymphoma 7C
BEGAIN brain-enriched guanylate kinase-associated
BST1 bone marrow stromal cell antigen 1
BYSL bystin-like
C12ORF49 chromosome 12 open reading frame 49
C17ORF70 chromosome 17 open reading frame 70
C17ORF75 chromosome 17 open reading frame 75
C1QTNF1 C1q and tumor necrosis factor related protein 1
C22ORF24 chromosome 22 open reading frame 24
C6ORF47 chromosome 6 open reading frame 47
CAMTA2 calmodulin binding transcription activator 2
CASD1 CAS1 domain containing 1
CD151 CD151 molecule (Raph blood group)
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CINP cyclin-dependent kinase 2 interacting protein
CLCN6 chloride channel, voltage-sensitive 6
CLEC16A C-type lectin domain family 16, member A
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
DAZAP1 DAZ associated protein 1
DDIT3 DNA-damage-inducible transcript 3
DMBT1 deleted in malignant brain tumors 1
DPF2 D4, zinc and double PHD fingers family 2
DRD5 dopamine receptor D5
DSN1 DSN1, MIS12 kinetochore complex component
FAF2 Fas associated factor family member 2
FAM188A family with sequence similarity 188, member A
FBXO5 F-box protein 5
FGL1 fibrinogen-like 1
FKBP9 FK506 binding protein 9, 63 kDa
FOXK2 forkhead box K2
FPGS folylpolyglutamate synthase
FZD2 frizzled class receptor 2
GMIP GEM interacting protein
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPR183 G protein-coupled receptor 183
HCAR3 hydroxycarboxylic acid receptor 3
HINFP histone H4 transcription factor
HLA-DMB major histocompatibility complex, class II, DM beta
IGSF6 immunoglobulin superfamily, member 6
KAT2B K(lysine) acetyltransferase 2B
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
LAMP5 lysosomal-associated membrane protein family, member 5
LMAN2L lectin, mannose-binding 2-like
LOC390998 ribosomal protein L10 pseudogene
LOC642236 FSHD region gene 1 pseudogene
LRRK1 leucine-rich repeat kinase 1
MAPK10 mitogen-activated protein kinase 10
MGAM maltase-glucoamylase
MID1IP1 MID1 interacting protein 1
MNAT1 MNAT CDK-activating kinase assembly factor 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
NDNF neuron-derived neurotrophic factor
NHEJ1 nonhomologous end-joining factor 1
NME3 NME/NM23 nucleoside diphosphate kinase 3
NT5E 5'-nucleotidase, ecto (CD73)
NT5M 5',3'-nucleotidase, mitochondrial
OR1D2 olfactory receptor, family 1, subfamily D, member 2
ORC2 origin recognition complex, subunit 2
PELI1 pellino E3 ubiquitin protein ligase 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLCD1 phospholipase C, delta 1
PPCDC phosphopantothenoylcysteine decarboxylase
PTTG3P pituitary tumor-transforming 3, pseudogene
RBM41 RNA binding motif protein 41
RNF11 ring finger protein 11
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
SAC3D1 SAC3 domain containing 1
SEPW1 selenoprotein W, 1
SIPA1 signal-induced proliferation-associated 1
SLC2A4RG SLC2A4 regulator
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12)
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
STAT4 signal transducer and activator of transcription 4
STX1A syntaxin 1A (brain)
TACC3 transforming, acidic coiled-coil containing protein 3
TCTN2 tectonic family member 2
TEFM transcription elongation factor, mitochondrial
TIPIN TIMELESS interacting protein
TMEM62 transmembrane protein 62
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TRIM66 tripartite motif containing 66
TRPM2 transient receptor potential cation channel, subfamily M, member 2
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBOX5 U-box domain containing 5
VASP vasodilator-stimulated phosphoprotein
XAF1 XIAP associated factor 1
ZC3H3 zinc finger CCCH-type containing 3
ZNF211 zinc finger protein 211
ZNF408 zinc finger protein 408
ZNF468 zinc finger protein 468
ZNF529 zinc finger protein 529