molsidomine-2862 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the molsidomine-2862 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADM adrenomedullin
AKAP8L A kinase (PRKA) anchor protein 8-like
ALPPL2 alkaline phosphatase, placental-like 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASMT acetylserotonin O-methyltransferase
C3ORF18 chromosome 3 open reading frame 18
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CD300A CD300a molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD79B CD79b molecule, immunoglobulin-associated beta
CD82 CD82 molecule
CDC25C cell division cycle 25C
CDK6 cyclin-dependent kinase 6
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CIDEB cell death-inducing DFFA-like effector b
CLEC4E C-type lectin domain family 4, member E
COLEC10 collectin sub-family member 10 (C-type lectin)
CTF1 cardiotrophin 1
DLC1 DLC1 Rho GTPase activating protein
DOK5 docking protein 5
DUSP10 dual specificity phosphatase 10
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EDN1 endothelin 1
FASTK Fas-activated serine/threonine kinase
FAT4 FAT atypical cadherin 4
FBN1 fibrillin 1
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FER1L4 fer-1-like family member 4, pseudogene (functional)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPSM3 G-protein signaling modulator 3
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HDAC6 histone deacetylase 6
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H4A histone cluster 1, H4a
HOXA10 homeobox A10
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
ICA1 islet cell autoantigen 1, 69kDa
IGHA1 immunoglobulin heavy constant alpha 1
IL20RA interleukin 20 receptor, alpha
INPP5J inositol polyphosphate-5-phosphatase J
KCTD17 potassium channel tetramerization domain containing 17
KLHL25 kelch-like family member 25
LAT2 linker for activation of T cells family, member 2
LATS1 large tumor suppressor kinase 1
LDB3 LIM domain binding 3
LIF leukemia inhibitory factor
LIMCH1 LIM and calponin homology domains 1
LMNA lamin A/C
MAPT microtubule-associated protein tau
MECOM MDS1 and EVI1 complex locus
MOCS1 molybdenum cofactor synthesis 1
MUC2 mucin 2, oligomeric mucus/gel-forming
N4BP3 NEDD4 binding protein 3
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NADK NAD kinase
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OSBPL10 oxysterol binding protein-like 10
PARD3 par-3 family cell polarity regulator
PCSK6 proprotein convertase subtilisin/kexin type 6
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PML promyelocytic leukemia
POU4F1 POU class 4 homeobox 1
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRAME preferentially expressed antigen in melanoma
RAB3B RAB3B, member RAS oncogene family
RAB6B RAB6B, member RAS oncogene family
RANBP3 RAN binding protein 3
RCAN3 RCAN family member 3
REPS1 RALBP1 associated Eps domain containing 1
RNF122 ring finger protein 122
SAPCD1 suppressor APC domain containing 1
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDS serine dehydratase
SETD1A SET domain containing 1A
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SH3BP2 SH3-domain binding protein 2
SIRPA signal-regulatory protein alpha
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
STAT2 signal transducer and activator of transcription 2, 113kDa
SVIL supervillin
SYN2 synapsin II
TBKBP1 TBK1 binding protein 1
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TP53I11 tumor protein p53 inducible protein 11
USP46 ubiquitin specific peptidase 46
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)
WDR55 WD repeat domain 55
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZFP64 ZFP64 zinc finger protein
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACADSB acyl-CoA dehydrogenase, short/branched chain
AFAP1 actin filament associated protein 1
AGMAT agmatine ureohydrolase (agmatinase)
ALS2CL ALS2 C-terminal like
ARHGAP10 Rho GTPase activating protein 10
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARMC4 armadillo repeat containing 4
ARSB arylsulfatase B
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF73 chromosome 11 open reading frame 73
C14ORF93 chromosome 14 open reading frame 93
C1ORF105 chromosome 1 open reading frame 105
C1ORF159 chromosome 1 open reading frame 159
CARF calcium responsive transcription factor
CCDC121 coiled-coil domain containing 121
CCDC85C coiled-coil domain containing 85C
CEP112 centrosomal protein 112kDa
CLK1 CDC-like kinase 1
CORO7 coronin 7
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CXORF56 chromosome X open reading frame 56
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DMTN dematin actin binding protein
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
ELOVL4 ELOVL fatty acid elongase 4
ETV6 ets variant 6
FAM184A family with sequence similarity 184, member A
FOSL1 FOS-like antigen 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GEMIN8 gem (nuclear organelle) associated protein 8
GLS2 glutaminase 2 (liver, mitochondrial)
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GPX2 glutathione peroxidase 2
HIST1H3B histone cluster 1, H3b
HIST1H4F histone cluster 1, H4f
IDI2-AS1 IDI2 antisense RNA 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0125 KIAA0125
KIAA0895 KIAA0895
LNPEP leucyl/cystinyl aminopeptidase
LOC390998 ribosomal protein L10 pseudogene
LOC729164 hCG1732469
LPPR1 lipid phosphate phosphatase-related protein type 1
MBNL3 muscleblind-like splicing regulator 3
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYOZ3 myozenin 3
NME6 NME/NM23 nucleoside diphosphate kinase 6
NOD1 nucleotide-binding oligomerization domain containing 1
NPIPB15 nuclear pore complex interacting protein family, member B15
PC pyruvate carboxylase
PDE12 phosphodiesterase 12
PILRB paired immunoglobin-like type 2 receptor beta
POLH polymerase (DNA directed), eta
POLL polymerase (DNA directed), lambda
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PTPRU protein tyrosine phosphatase, receptor type, U
PVRL3 poliovirus receptor-related 3
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RETN resistin
RLN1 relaxin 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SIRT6 sirtuin 6
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SREK1IP1 SREK1-interacting protein 1
SSBP3 single stranded DNA binding protein 3
SYBU syntabulin (syntaxin-interacting)
TBC1D19 TBC1 domain family, member 19
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFF2 trefoil factor 2
TH tyrosine hydroxylase
TLN1 talin 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TNS2 tensin 2
TRAPPC13 trafficking protein particle complex 13
TRIM36 tripartite motif containing 36
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TWISTNB TWIST neighbor
USB1 U6 snRNA biogenesis 1
XKR8 XK, Kell blood group complex subunit-related family, member 8
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF324 zinc finger protein 324
ZNF37BP zinc finger protein 37B, pseudogene
ZNF639 zinc finger protein 639