molsidomine-6325 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the molsidomine-6325 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ADARB1 adenosine deaminase, RNA-specific, B1
ADGRL2 adhesion G protein-coupled receptor L2
ALG12 ALG12, alpha-1,6-mannosyltransferase
APOL6 apolipoprotein L, 6
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ARMC8 armadillo repeat containing 8
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATP5SL ATP5S-like
BMP8A bone morphogenetic protein 8a
C9ORF40 chromosome 9 open reading frame 40
CALD1 caldesmon 1
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLCN6 chloride channel, voltage-sensitive 6
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNTNAP2 contactin associated protein-like 2
COL8A2 collagen, type VIII, alpha 2
CTIF CBP80/20-dependent translation initiation factor
CTNND2 catenin (cadherin-associated protein), delta 2
CUZD1 CUB and zona pellucida-like domains 1
DCTN1 dynactin 1
DCTN2 dynactin 2 (p50)
DDN dendrin
DEPTOR DEP domain containing MTOR-interacting protein
EIF1 eukaryotic translation initiation factor 1
EN1 engrailed homeobox 1
ETV5 ets variant 5
FAM134B family with sequence similarity 134, member B
FH fumarate hydratase
FOXP3 forkhead box P3
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GLS2 glutaminase 2 (liver, mitochondrial)
GPC1 glypican 1
GSK3A glycogen synthase kinase 3 alpha
GTF2A1 general transcription factor IIA, 1, 19/37kDa
ICOS inducible T-cell co-stimulator
IFT122 intraflagellar transport 122
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL15 interleukin 15
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IVL involucrin
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KCTD13 potassium channel tetramerization domain containing 13
KRT33A keratin 33A, type I
LAMC3 laminin, gamma 3
LARP4B La ribonucleoprotein domain family, member 4B
LDB1 LIM domain binding 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MED18 mediator complex subunit 18
MUC5B mucin 5B, oligomeric mucus/gel-forming
MVK mevalonate kinase
MXD3 MAX dimerization protein 3
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic
NEB nebulin
NF1 neurofibromin 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NPAS3 neuronal PAS domain protein 3
NRXN3 neurexin 3
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PDE4DIP phosphodiesterase 4D interacting protein
PECAM1 platelet/endothelial cell adhesion molecule 1
PHF7 PHD finger protein 7
PLIN2 perilipin 2
PMFBP1 polyamine modulated factor 1 binding protein 1
PNMA2 paraneoplastic Ma antigen 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PTEN phosphatase and tensin homolog
RAB36 RAB36, member RAS oncogene family
REC8 REC8 meiotic recombination protein
RGS12 regulator of G-protein signaling 12
RHOT2 ras homolog family member T2
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNF19B ring finger protein 19B
RPL35A ribosomal protein L35a
SARM1 sterile alpha and TIR motif containing 1
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SIRT6 sirtuin 6
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TBX2 T-box 2
TCP11 t-complex 11, testis-specific
TMEM63A transmembrane protein 63A
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOP3A topoisomerase (DNA) III alpha
TRD T cell receptor delta locus
TTC38 tetratricopeptide repeat domain 38
UBE4B ubiquitination factor E4B
VNN2 vanin 2
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZNF174 zinc finger protein 174
ZNF286A zinc finger protein 286A

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ADGRG2 adhesion G protein-coupled receptor G2
AEN apoptosis enhancing nuclease
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALS2CL ALS2 C-terminal like
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ASCC2 activating signal cointegrator 1 complex subunit 2
BAK1 BCL2-antagonist/killer 1
BANK1 B-cell scaffold protein with ankyrin repeats 1
BATF3 basic leucine zipper transcription factor, ATF-like 3
C11ORF63 chromosome 11 open reading frame 63
C21ORF91 chromosome 21 open reading frame 91
CCDC106 coiled-coil domain containing 106
CCNJ cyclin J
CCNT1 cyclin T1
CDH3 cadherin 3, type 1, P-cadherin (placental)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CRELD1 cysteine-rich with EGF-like domains 1
CTC1 CTS telomere maintenance complex component 1
DCLRE1B DNA cross-link repair 1B
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
EHD3 EH-domain containing 3
EPHA4 EPH receptor A4
FAM86C1 family with sequence similarity 86, member C1
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FXYD3 FXYD domain containing ion transport regulator 3
GRWD1 glutamate-rich WD repeat containing 1
GTPBP2 GTP binding protein 2
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HIST1H2AJ histone cluster 1, H2aj
HOXA4 homeobox A4
HSPA2 heat shock 70kDa protein 2
IRF1 interferon regulatory factor 1
IRF2 interferon regulatory factor 2
IRF9 interferon regulatory factor 9
KIAA0556 KIAA0556
LIMS2 LIM and senescent cell antigen-like domains 2
LMNB1 lamin B1
LPAR6 lysophosphatidic acid receptor 6
LZTR1 leucine-zipper-like transcription regulator 1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCMBP minichromosome maintenance complex binding protein
MCOLN1 mucolipin 1
MOGS mannosyl-oligosaccharide glucosidase
MRPL41 mitochondrial ribosomal protein L41
MT1M metallothionein 1M
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYO1E myosin IE
NBAS neuroblastoma amplified sequence
NRSN2 neurensin 2
NRTN neurturin
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSTF1 osteoclast stimulating factor 1
PALMD palmdelphin
PC pyruvate carboxylase
PHLDA3 pleckstrin homology-like domain, family A, member 3
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PILRB paired immunoglobin-like type 2 receptor beta
PKN1 protein kinase N1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PORCN porcupine homolog (Drosophila)
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PPT2 palmitoyl-protein thioesterase 2
PRAME preferentially expressed antigen in melanoma
PRMT7 protein arginine methyltransferase 7
PRR3 proline rich 3
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RGS17 regulator of G-protein signaling 17
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
S100A9 S100 calcium binding protein A9
SH2D4A SH2 domain containing 4A
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPAG4 sperm associated antigen 4
STAG3 stromal antigen 3
STIM1 stromal interaction molecule 1
SUGCT succinyl-CoA:glutarate-CoA transferase
TBX19 T-box 19
TDRD7 tudor domain containing 7
THBS3 thrombospondin 3
THOP1 thimet oligopeptidase 1
TMEM132A transmembrane protein 132A
TMEM209 transmembrane protein 209
TMEM62 transmembrane protein 62
TOE1 target of EGR1, member 1 (nuclear)
TRIP10 thyroid hormone receptor interactor 10
TUBA3C tubulin, alpha 3c
TUBG2 tubulin, gamma 2
URM1 ubiquitin related modifier 1
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF571 zinc finger protein 571
ZNF675 zinc finger protein 675
ZNF692 zinc finger protein 692
ZNF862 zinc finger protein 862