mometasone-5541 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the mometasone-5541 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ADAM29 ADAM metallopeptidase domain 29
ADD2 adducin 2 (beta)
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AHI1 Abelson helper integration site 1
APP amyloid beta (A4) precursor protein
ATF6B activating transcription factor 6 beta
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BAX BCL2-associated X protein
C2ORF27A chromosome 2 open reading frame 27A
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CD79B CD79b molecule, immunoglobulin-associated beta
CD80 CD80 molecule
CDC14B cell division cycle 14B
CETN1 centrin, EF-hand protein, 1
CHRD chordin
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLGN calmegin
CLIC2 chloride intracellular channel 2
COL8A1 collagen, type VIII, alpha 1
CROCC ciliary rootlet coiled-coil, rootletin
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CYHR1 cysteine/histidine-rich 1
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
DCX doublecortin
DENND1C DENN/MADD domain containing 1C
DHODH dihydroorotate dehydrogenase (quinone)
EAF2 ELL associated factor 2
EGOT eosinophil granule ontogeny transcript (non-protein coding)
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
FKBP5 FK506 binding protein 5
FSTL3 follistatin-like 3 (secreted glycoprotein)
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR137 G protein-coupled receptor 137
HIST1H1E histone cluster 1, H1e
HLA-G major histocompatibility complex, class I, G
HNMT histamine N-methyltransferase
IL1B interleukin 1, beta
IL22 interleukin 22
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
JAK2 Janus kinase 2
KCNK1 potassium channel, two pore domain subfamily K, member 1
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KLHL20 kelch-like family member 20
KRT16 keratin 16, type I
KRT17 keratin 17, type I
LRRC75B leucine rich repeat containing 75B
LTBP2 latent transforming growth factor beta binding protein 2
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MT1F metallothionein 1F
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MXD3 MAX dimerization protein 3
MYLK myosin light chain kinase
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NCKIPSD NCK interacting protein with SH3 domain
NEK9 NIMA-related kinase 9
PDC phosducin
PRND prion protein 2 (dublet)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTPRD protein tyrosine phosphatase, receptor type, D
PXN paxillin
QPCTL glutaminyl-peptide cyclotransferase-like
QTRT1 queuine tRNA-ribosyltransferase 1
RAB35 RAB35, member RAS oncogene family
RHEB Ras homolog enriched in brain
RND1 Rho family GTPase 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SIRT3 sirtuin 3
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC35E2 solute carrier family 35, member E2
SMAD4 SMAD family member 4
SOCS7 suppressor of cytokine signaling 7
STK17A serine/threonine kinase 17a
STMN1 stathmin 1
STX7 syntaxin 7
SUGP1 SURP and G patch domain containing 1
SUN1 Sad1 and UNC84 domain containing 1
SYBU syntabulin (syntaxin-interacting)
SYK spleen tyrosine kinase
TAS2R1 taste receptor, type 2, member 1
TAZ tafazzin
TBX5 T-box 5
TET3 tet methylcytosine dioxygenase 3
TGM2 transglutaminase 2
TRIM15 tripartite motif containing 15
TRIP11 thyroid hormone receptor interactor 11
USP2 ubiquitin specific peptidase 2
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
ZBTB18 zinc finger and BTB domain containing 18
ZFPL1 zinc finger protein-like 1
ZNF747 zinc finger protein 747
ZYX zyxin

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
AHDC1 AT hook, DNA binding motif, containing 1
ALPK1 alpha-kinase 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
BBC3 BCL2 binding component 3
BIRC7 baculoviral IAP repeat containing 7
BRPF1 bromodomain and PHD finger containing, 1
C1ORF35 chromosome 1 open reading frame 35
C1QTNF3 C1q and tumor necrosis factor related protein 3
C4ORF29 chromosome 4 open reading frame 29
C5ORF45 chromosome 5 open reading frame 45
C8ORF60 chromosome 8 open reading frame 60
CCNL2 cyclin L2
CES3 carboxylesterase 3
CFAP44 cilia and flagella associated protein 44
CHPF chondroitin polymerizing factor
CLCN2 chloride channel, voltage-sensitive 2
CLSPN claspin
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHRS11 dehydrogenase/reductase (SDR family) member 11
ETNK2 ethanolamine kinase 2
FBXL15 F-box and leucine-rich repeat protein 15
FUZ fuzzy planar cell polarity protein
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPATCH2L G patch domain containing 2-like
GPX2 glutathione peroxidase 2
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HHLA3 HERV-H LTR-associating 3
HIST1H2BJ histone cluster 1, H2bj
HPSE heparanase
IFT22 intraflagellar transport 22
IMPG2 interphotoreceptor matrix proteoglycan 2
INPPL1 inositol polyphosphate phosphatase-like 1
IPP intracisternal A particle-promoted polypeptide
IRF9 interferon regulatory factor 9
ITPKB inositol-trisphosphate 3-kinase B
KIF3B kinesin family member 3B
LMO2 LIM domain only 2 (rhombotin-like 1)
LRP2 low density lipoprotein receptor-related protein 2
LRRC8D leucine rich repeat containing 8 family, member D
MBNL3 muscleblind-like splicing regulator 3
MBTD1 mbt domain containing 1
MECR mitochondrial trans-2-enoyl-CoA reductase
MFSD11 major facilitator superfamily domain containing 11
MPI mannose phosphate isomerase
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NIPAL2 NIPA-like domain containing 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
ONECUT2 one cut homeobox 2
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PROCR protein C receptor, endothelial
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PVRL3 poliovirus receptor-related 3
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RANGRF RAN guanine nucleotide release factor
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RFTN1 raftlin, lipid raft linker 1
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF121 ring finger protein 121
RNF122 ring finger protein 122
RNF2 ring finger protein 2
RNF43 ring finger protein 43
RPH3AL rabphilin 3A-like (without C2 domains)
RPL23AP32 ribosomal protein L23a pseudogene 32
SALL2 spalt-like transcription factor 2
SCGB2A2 secretoglobin, family 2A, member 2
SIRAL2 SIR2 antiphage like 2
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAOK1 TAO kinase 1
TCTN1 tectonic family member 1
THUMPD2 THUMP domain containing 2
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM134 transmembrane protein 134
TMUB2 transmembrane and ubiquitin-like domain containing 2
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TTC30A tetratricopeptide repeat domain 30A
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
VWA1 von Willebrand factor A domain containing 1
WDR76 WD repeat domain 76
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF160 zinc finger protein 160
ZNF205 zinc finger protein 205
ZNF276 zinc finger protein 276
ZNF442 zinc finger protein 442
ZNF446 zinc finger protein 446
ZNF480 zinc finger protein 480
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652