| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the monastrol-311 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ABLIM3 | actin binding LIM protein family, member 3 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| AKAP17A | A kinase (PRKA) anchor protein 17A |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ARFRP1 | ADP-ribosylation factor related protein 1 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ARPC4 | actin related protein 2/3 complex, subunit 4, 20kDa |
| ARRB1 | arrestin, beta 1 |
| ARSA | arylsulfatase A |
| ATG13 | autophagy related 13 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| B3GAT3 | beta-1,3-glucuronyltransferase 3 |
| BICD2 | bicaudal D homolog 2 (Drosophila) |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C16ORF59 | chromosome 16 open reading frame 59 |
| CDK10 | cyclin-dependent kinase 10 |
| CDYL | chromodomain protein, Y-like |
| CHAT | choline O-acetyltransferase |
| CNPY3 | canopy FGF signaling regulator 3 |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DST | dystonin |
| DVL2 | dishevelled segment polarity protein 2 |
| EFHC1 | EF-hand domain (C-terminal) containing 1 |
| EFNB3 | ephrin-B3 |
| ERO1L | ERO1-like (S. cerevisiae) |
| FGFR4 | fibroblast growth factor receptor 4 |
| FOSL1 | FOS-like antigen 1 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GMIP | GEM interacting protein |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| HLA-C | major histocompatibility complex, class I, C |
| HMHA1 | histocompatibility (minor) HA-1 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IL11 | interleukin 11 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
| KCTD13 | potassium channel tetramerization domain containing 13 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KIAA0141 | KIAA0141 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| L1CAM | L1 cell adhesion molecule |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LIAS | lipoic acid synthetase |
| LPPR2 | lipid phosphate phosphatase-related protein type 2 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) |
| MAGEA3 | melanoma antigen family A3 |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
| MICALL1 | MICAL-like 1 |
| MPPE1 | metallophosphoesterase 1 |
| MT1HL1 | metallothionein 1H-like 1 |
| MYL10 | myosin, light chain 10, regulatory |
| MYO9B | myosin IXB |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NCLN | nicalin |
| NMT1 | N-myristoyltransferase 1 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| OLFML2A | olfactomedin-like 2A |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PCDHB12 | protocadherin beta 12 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase |
| PLEK2 | pleckstrin 2 |
| PPP2R2D | protein phosphatase 2, regulatory subunit B, delta |
| PRSS50 | protease, serine, 50 |
| PYGB | phosphorylase, glycogen; brain |
| RAB4B | RAB4B, member RAS oncogene family |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RNF25 | ring finger protein 25 |
| RNFT2 | ring finger protein, transmembrane 2 |
| RPLP2 | ribosomal protein, large, P2 |
| RRAS | related RAS viral (r-ras) oncogene homolog |
| RUNDC3A | RUN domain containing 3A |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SQSTM1 | sequestosome 1 |
| THTPA | thiamine triphosphatase |
| TIMM44 | translocase of inner mitochondrial membrane 44 homolog (yeast) |
| TMC6 | transmembrane channel-like 6 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRAPPC12 | trafficking protein particle complex 12 |
| TRIM23 | tripartite motif containing 23 |
| TRIM3 | tripartite motif containing 3 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TTC22 | tetratricopeptide repeat domain 22 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| VARS | valyl-tRNA synthetase |
| WDR25 | WD repeat domain 25 |
| WDR91 | WD repeat domain 91 |
| WIZ | widely interspaced zinc finger motifs |
| YY1 | YY1 transcription factor |
| ZFP36 | ZFP36 ring finger protein |
| ZNF446 | zinc finger protein 446 |
| Symbol | Name |
|---|---|
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| AGBL2 | ATP/GTP binding protein-like 2 |
| ALPK1 | alpha-kinase 1 |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CA6 | carbonic anhydrase VI |
| CACNG2 | calcium channel, voltage-dependent, gamma subunit 2 |
| CD300C | CD300c molecule |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDK20 | cyclin-dependent kinase 20 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CH25H | cholesterol 25-hydroxylase |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CLDN1 | claudin 1 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CRLF2 | cytokine receptor-like factor 2 |
| CRYGA | crystallin, gamma A |
| CTLA4 | cytotoxic T-lymphocyte-associated protein 4 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYSLTR2 | cysteinyl leukotriene receptor 2 |
| DCSTAMP | dendrocyte expressed seven transmembrane protein |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DYSF | dysferlin |
| EFCAB1 | EF-hand calcium binding domain 1 |
| ESPN | espin |
| EVPL | envoplakin |
| F7 | coagulation factor VII (serum prothrombin conversion accelerator) |
| FOXC1 | forkhead box C1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAGE3 | G antigen 3 |
| GALR3 | galanin receptor 3 |
| GAS8-AS1 | GAS8 antisense RNA 1 |
| HCG9 | HLA complex group 9 (non-protein coding) |
| HMGA2 | high mobility group AT-hook 2 |
| HOPX | HOP homeobox |
| HOXB9 | homeobox B9 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| ITGA8 | integrin, alpha 8 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLHL4 | kelch-like family member 4 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 |
| LIN28A | lin-28 homolog A (C. elegans) |
| LIN7A | lin-7 homolog A (C. elegans) |
| LOC441601 | septin 7 pseudogene |
| LRRC6 | leucine rich repeat containing 6 |
| MAGEA5 | melanoma antigen family A5 |
| MED31 | mediator complex subunit 31 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MNT | MAX network transcriptional repressor |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NDST4 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 |
| NR1I3 | nuclear receptor subfamily 1, group I, member 3 |
| NYX | nyctalopin |
| ONECUT2 | one cut homeobox 2 |
| OXT | oxytocin/neurophysin I prepropeptide |
| PHOX2A | paired-like homeobox 2a |
| PIP | prolactin-induced protein |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PRLH | prolactin releasing hormone |
| PTPRT | protein tyrosine phosphatase, receptor type, T |
| RAB33A | RAB33A, member RAS oncogene family |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| RLN1 | relaxin 1 |
| RPH3A | rabphilin 3A |
| RPS17P5 | ribosomal protein S17 pseudogene 5 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SCNN1D | sodium channel, non voltage gated 1 delta subunit |
| SIGLEC5 | sialic acid binding Ig-like lectin 5 |
| SLC28A1 | solute carrier family 28 (concentrative nucleoside transporter), member 1 |
| SLC39A2 | solute carrier family 39 (zinc transporter), member 2 |
| SPATA7 | spermatogenesis associated 7 |
| SPP1 | secreted phosphoprotein 1 |
| SPP2 | secreted phosphoprotein 2, 24kDa |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SYN1 | synapsin I |
| TEX13B | testis expressed 13B |
| TGM5 | transglutaminase 5 |
| TMEM140 | transmembrane protein 140 |
| TMPRSS6 | transmembrane protease, serine 6 |
| TNNC2 | troponin C type 2 (fast) |
| TSHZ2 | teashirt zinc finger homeobox 2 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VN1R1 | vomeronasal 1 receptor 1 |
| WNT2 | wingless-type MMTV integration site family member 2 |
| ZBED2 | zinc finger, BED-type containing 2 |
| ZC4H2 | zinc finger, C4H2 domain containing |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 |
| ZNF140 | zinc finger protein 140 |
| ZNF816 | zinc finger protein 816 |