monastrol-311 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the monastrol-311 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABLIM3 actin binding LIM protein family, member 3
ADAM22 ADAM metallopeptidase domain 22
AKAP17A A kinase (PRKA) anchor protein 17A
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ARFRP1 ADP-ribosylation factor related protein 1
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ARRB1 arrestin, beta 1
ARSA arylsulfatase A
ATG13 autophagy related 13
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
B3GAT3 beta-1,3-glucuronyltransferase 3
BICD2 bicaudal D homolog 2 (Drosophila)
BIK BCL2-interacting killer (apoptosis-inducing)
C16ORF59 chromosome 16 open reading frame 59
CDK10 cyclin-dependent kinase 10
CDYL chromodomain protein, Y-like
CHAT choline O-acetyltransferase
CNPY3 canopy FGF signaling regulator 3
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DST dystonin
DVL2 dishevelled segment polarity protein 2
EFHC1 EF-hand domain (C-terminal) containing 1
EFNB3 ephrin-B3
ERO1L ERO1-like (S. cerevisiae)
FGFR4 fibroblast growth factor receptor 4
FOSL1 FOS-like antigen 1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GMIP GEM interacting protein
GNA14 guanine nucleotide binding protein (G protein), alpha 14
HLA-C major histocompatibility complex, class I, C
HMHA1 histocompatibility (minor) HA-1
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IL11 interleukin 11
ITPKB inositol-trisphosphate 3-kinase B
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCTD13 potassium channel tetramerization domain containing 13
KDM4B lysine (K)-specific demethylase 4B
KIAA0141 KIAA0141
KRI1 KRI1 homolog (S. cerevisiae)
L1CAM L1 cell adhesion molecule
LGALS8 lectin, galactoside-binding, soluble, 8
LIAS lipoic acid synthetase
LPPR2 lipid phosphate phosphatase-related protein type 2
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAGEA3 melanoma antigen family A3
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MICALL1 MICAL-like 1
MPPE1 metallophosphoesterase 1
MT1HL1 metallothionein 1H-like 1
MYL10 myosin, light chain 10, regulatory
MYO9B myosin IXB
NCAPH2 non-SMC condensin II complex, subunit H2
NCLN nicalin
NMT1 N-myristoyltransferase 1
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
OLFML2A olfactomedin-like 2A
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCDHB12 protocadherin beta 12
PCSK7 proprotein convertase subtilisin/kexin type 7
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PLEK2 pleckstrin 2
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PRSS50 protease, serine, 50
PYGB phosphorylase, glycogen; brain
RAB4B RAB4B, member RAS oncogene family
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RNF25 ring finger protein 25
RNFT2 ring finger protein, transmembrane 2
RPLP2 ribosomal protein, large, P2
RRAS related RAS viral (r-ras) oncogene homolog
RUNDC3A RUN domain containing 3A
SBNO2 strawberry notch homolog 2 (Drosophila)
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SPTBN1 spectrin, beta, non-erythrocytic 1
SQSTM1 sequestosome 1
THTPA thiamine triphosphatase
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast)
TMC6 transmembrane channel-like 6
TRAK1 trafficking protein, kinesin binding 1
TRAPPC12 trafficking protein particle complex 12
TRIM23 tripartite motif containing 23
TRIM3 tripartite motif containing 3
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TTC22 tetratricopeptide repeat domain 22
TTLL4 tubulin tyrosine ligase-like family member 4
VARS valyl-tRNA synthetase
WDR25 WD repeat domain 25
WDR91 WD repeat domain 91
WIZ widely interspaced zinc finger motifs
YY1 YY1 transcription factor
ZFP36 ZFP36 ring finger protein
ZNF446 zinc finger protein 446

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
AGBL2 ATP/GTP binding protein-like 2
ALPK1 alpha-kinase 1
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
CA5BP1 carbonic anhydrase VB pseudogene 1
CA6 carbonic anhydrase VI
CACNG2 calcium channel, voltage-dependent, gamma subunit 2
CD300C CD300c molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CDADC1 cytidine and dCMP deaminase domain containing 1
CDK20 cyclin-dependent kinase 20
CDKL3 cyclin-dependent kinase-like 3
CH25H cholesterol 25-hydroxylase
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLDN1 claudin 1
CNTD2 cyclin N-terminal domain containing 2
CRLF2 cytokine receptor-like factor 2
CRYGA crystallin, gamma A
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNBIP1 catenin, beta interacting protein 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYSLTR2 cysteinyl leukotriene receptor 2
DCSTAMP dendrocyte expressed seven transmembrane protein
DHRS9 dehydrogenase/reductase (SDR family) member 9
DYSF dysferlin
EFCAB1 EF-hand calcium binding domain 1
ESPN espin
EVPL envoplakin
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FOXC1 forkhead box C1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAGE3 G antigen 3
GALR3 galanin receptor 3
GAS8-AS1 GAS8 antisense RNA 1
HCG9 HLA complex group 9 (non-protein coding)
HMGA2 high mobility group AT-hook 2
HOPX HOP homeobox
HOXB9 homeobox B9
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ITGA8 integrin, alpha 8
KDM8 lysine (K)-specific demethylase 8
KLHL4 kelch-like family member 4
KLRB1 killer cell lectin-like receptor subfamily B, member 1
LIN28A lin-28 homolog A (C. elegans)
LIN7A lin-7 homolog A (C. elegans)
LOC441601 septin 7 pseudogene
LRRC6 leucine rich repeat containing 6
MAGEA5 melanoma antigen family A5
MED31 mediator complex subunit 31
MNMIP1 manchette microtubule inner protein 1
MNT MAX network transcriptional repressor
MTERF4 mitochondrial transcription termination factor 4
MUC2 mucin 2, oligomeric mucus/gel-forming
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
NR1I3 nuclear receptor subfamily 1, group I, member 3
NYX nyctalopin
ONECUT2 one cut homeobox 2
OXT oxytocin/neurophysin I prepropeptide
PHOX2A paired-like homeobox 2a
PIP prolactin-induced protein
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PRLH prolactin releasing hormone
PTPRT protein tyrosine phosphatase, receptor type, T
RAB33A RAB33A, member RAS oncogene family
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RLN1 relaxin 1
RPH3A rabphilin 3A
RPS17P5 ribosomal protein S17 pseudogene 5
SAG S-antigen; retina and pineal gland (arrestin)
SCNN1D sodium channel, non voltage gated 1 delta subunit
SIGLEC5 sialic acid binding Ig-like lectin 5
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC39A2 solute carrier family 39 (zinc transporter), member 2
SPATA7 spermatogenesis associated 7
SPP1 secreted phosphoprotein 1
SPP2 secreted phosphoprotein 2, 24kDa
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SYN1 synapsin I
TEX13B testis expressed 13B
TGM5 transglutaminase 5
TMEM140 transmembrane protein 140
TMPRSS6 transmembrane protease, serine 6
TNNC2 troponin C type 2 (fast)
TSHZ2 teashirt zinc finger homeobox 2
UNC93B1 unc-93 homolog B1 (C. elegans)
VEZT vezatin, adherens junctions transmembrane protein
VN1R1 vomeronasal 1 receptor 1
WNT2 wingless-type MMTV integration site family member 2
ZBED2 zinc finger, BED-type containing 2
ZC4H2 zinc finger, C4H2 domain containing
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF140 zinc finger protein 140
ZNF816 zinc finger protein 816