| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the monastrol-596 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| AGGF1 | angiogenic factor with G patch and FHA domains 1 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked |
| B3GAT3 | beta-1,3-glucuronyltransferase 3 |
| BCL2L1 | BCL2-like 1 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| C20ORF27 | chromosome 20 open reading frame 27 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| C3ORF52 | chromosome 3 open reading frame 52 |
| CA7 | carbonic anhydrase VII |
| CCHCR1 | coiled-coil alpha-helical rod protein 1 |
| CCSER2 | coiled-coil serine-rich protein 2 |
| CD44 | CD44 molecule (Indian blood group) |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHERP | calcium homeostasis endoplasmic reticulum protein |
| COG5 | component of oligomeric golgi complex 5 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
| CRTC1 | CREB regulated transcription coactivator 1 |
| DMWD | dystrophia myotonica, WD repeat containing |
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 |
| ELMO2 | engulfment and cell motility 2 |
| EPN3 | epsin 3 |
| ERF | Ets2 repressor factor |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FGFR4 | fibroblast growth factor receptor 4 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 |
| GLRX | glutaredoxin (thioltransferase) |
| HPX | hemopexin |
| HUS1 | HUS1 checkpoint homolog (S. pombe) |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KIAA0141 | KIAA0141 |
| LIG3 | ligase III, DNA, ATP-dependent |
| LIM2 | lens intrinsic membrane protein 2, 19kDa |
| LPAR1 | lysophosphatidic acid receptor 1 |
| LRRC1 | leucine rich repeat containing 1 |
| MAP2K3 | mitogen-activated protein kinase kinase 3 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MFAP3L | microfibrillar-associated protein 3-like |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NADK | NAD kinase |
| NCKAP1 | NCK-associated protein 1 |
| NDN | necdin, melanoma antigen (MAGE) family member |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| NPY | neuropeptide Y |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 |
| PCGF1 | polycomb group ring finger 1 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PLCG1 | phospholipase C, gamma 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PROL1 | proline rich, lacrimal 1 |
| PTRF | polymerase I and transcript release factor |
| RNF141 | ring finger protein 141 |
| RNF24 | ring finger protein 24 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RRAS | related RAS viral (r-ras) oncogene homolog |
| SCAMP1 | secretory carrier membrane protein 1 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) |
| SEC24D | SEC24 family member D |
| SERBP1 | SERPINE1 mRNA binding protein 1 |
| SERINC3 | serine incorporator 3 |
| SGMS1 | sphingomyelin synthase 1 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SORT1 | sortilin 1 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SQSTM1 | sequestosome 1 |
| SRP72 | signal recognition particle 72kDa |
| SRSF8 | serine/arginine-rich splicing factor 8 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TK2 | thymidine kinase 2, mitochondrial |
| TMEM161A | transmembrane protein 161A |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TNS2 | tensin 2 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TSPAN32 | tetraspanin 32 |
| URM1 | ubiquitin related modifier 1 |
| VASP | vasodilator-stimulated phosphoprotein |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WSCD1 | WSC domain containing 1 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF710 | zinc finger protein 710 |
| Symbol | Name |
|---|---|
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CACNA1S | calcium channel, voltage-dependent, L type, alpha 1S subunit |
| CFAP70 | cilia and flagella associated protein 70 |
| CHKB | choline kinase beta |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| COX17 | COX17 cytochrome c oxidase copper chaperone |
| CTSD | cathepsin D |
| DAGLA | diacylglycerol lipase, alpha |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DCP1A | decapping mRNA 1A |
| DIXDC1 | DIX domain containing 1 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 |
| DRP2 | dystrophin related protein 2 |
| DUSP8 | dual specificity phosphatase 8 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| ECE2 | endothelin converting enzyme 2 |
| EFNA3 | ephrin-A3 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ENO3 | enolase 3 (beta, muscle) |
| EPHA4 | EPH receptor A4 |
| EPX | eosinophil peroxidase |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM114A2 | family with sequence similarity 114, member A2 |
| FZD2 | frizzled class receptor 2 |
| GABRG2 | gamma-aminobutyric acid (GABA) A receptor, gamma 2 |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GMIP | GEM interacting protein |
| H2AFJ | H2A histone family, member J |
| HABP2 | hyaluronan binding protein 2 |
| HCG4B | HLA complex group 4B (non-protein coding) |
| HEATR3 | HEAT repeat containing 3 |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H4J | histone cluster 1, H4j |
| HOXC4 | homeobox C4 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IL19 | interleukin 19 |
| INSIG2 | insulin induced gene 2 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KCNC3 | potassium channel, voltage gated Shaw related subfamily C, member 3 |
| KCNJ14 | potassium channel, inwardly rectifying subfamily J, member 14 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KIF5A | kinesin family member 5A |
| KLHL26 | kelch-like family member 26 |
| KPTN | kaptin (actin binding protein) |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LMNB2 | lamin B2 |
| LOC145678 | uncharacterized LOC145678 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MGP | matrix Gla protein |
| MOSPD3 | motile sperm domain containing 3 |
| MYL5 | myosin, light chain 5, regulatory |
| MYOZ3 | myozenin 3 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| OMG | oligodendrocyte myelin glycoprotein |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PELP1 | proline, glutamate and leucine rich protein 1 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PPP2R2D | protein phosphatase 2, regulatory subunit B, delta |
| PQLC3 | PQ loop repeat containing 3 |
| PRKCE | protein kinase C, epsilon |
| PRSS2 | protease, serine, 2 (trypsin 2) |
| PTGES2 | prostaglandin E synthase 2 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RNF43 | ring finger protein 43 |
| SCNN1G | sodium channel, non voltage gated 1 gamma subunit |
| SDC3 | syndecan 3 |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) |
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 |
| SNHG20 | small nucleolar RNA host gene 20 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| STAB2 | stabilin 2 |
| STX1A | syntaxin 1A (brain) |
| TCP10 | t-complex 10 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TMEM121 | transmembrane protein 121 |
| TMEM246 | transmembrane protein 246 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TRIM25 | tripartite motif containing 25 |
| TUBA4B | tubulin, alpha 4b |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UBQLN4 | ubiquilin 4 |
| ZFHX4 | zinc finger homeobox 4 |
| ZNF134 | zinc finger protein 134 |
| ZNF250 | zinc finger protein 250 |
| ZNF408 | zinc finger protein 408 |
| ZNF74 | zinc finger protein 74 |
| ZNF768 | zinc finger protein 768 |
