| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the monastrol-610 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| AGFG2 | ArfGAP with FG repeats 2 |
| ANO10 | anoctamin 10 |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATXN8OS | ATXN8 opposite strand (non-protein coding) |
| BCL3 | B-cell CLL/lymphoma 3 |
| BMP8A | bone morphogenetic protein 8a |
| C3ORF52 | chromosome 3 open reading frame 52 |
| CALU | calumenin |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| CCS | copper chaperone for superoxide dismutase |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CTRC | chymotrypsin C (caldecrin) |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| DEFA4 | defensin, alpha 4, corticostatin |
| DENND1C | DENN/MADD domain containing 1C |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DND1 | DND microRNA-mediated repression inhibitor 1 |
| EFNB3 | ephrin-B3 |
| EGR4 | early growth response 4 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
| EPS8L1 | EPS8-like 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM162A | family with sequence similarity 162, member A |
| FCGR1B | Fc fragment of IgG, high affinity Ib, receptor (CD64) |
| FHL3 | four and a half LIM domains 3 |
| FLT3 | fms-related tyrosine kinase 3 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 |
| GLRX | glutaredoxin (thioltransferase) |
| GPR3 | G protein-coupled receptor 3 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HHIPL2 | HHIP-like 2 |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| IDUA | iduronidase, alpha-L- |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IL19 | interleukin 19 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IL1RN | interleukin 1 receptor antagonist |
| ITK | IL2-inducible T-cell kinase |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KLK13 | kallikrein-related peptidase 13 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LRRC23 | leucine rich repeat containing 23 |
| LZTS1 | leucine zipper, putative tumor suppressor 1 |
| MAP4 | microtubule-associated protein 4 |
| MASP1 | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MED28 | mediator complex subunit 28 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NADK | NAD kinase |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NEBL | nebulette |
| NEMF | nuclear export mediator factor |
| NF1 | neurofibromin 1 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NPTX1 | neuronal pentraxin I |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OBSL1 | obscurin-like 1 |
| OLFM1 | olfactomedin 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PDE6D | phosphodiesterase 6D, cGMP-specific, rod, delta |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 |
| PP14571 | uncharacterized LOC100130449 |
| PRPH2 | peripherin 2 (retinal degeneration, slow) |
| RCAN1 | regulator of calcineurin 1 |
| RGS14 | regulator of G-protein signaling 14 |
| RUNX2 | runt-related transcription factor 2 |
| SCAMP1 | secretory carrier membrane protein 1 |
| SGCE | sarcoglycan, epsilon |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SIRPA | signal-regulatory protein alpha |
| SMC5 | structural maintenance of chromosomes 5 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| SPRR1B | small proline-rich protein 1B |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| STK19 | serine/threonine kinase 19 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TGFA | transforming growth factor, alpha |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TP53TG1 | TP53 target 1 (non-protein coding) |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TRAM2 | translocation associated membrane protein 2 |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM3 | tripartite motif containing 3 |
| TSPYL2 | TSPY-like 2 |
| VRK3 | vaccinia related kinase 3 |
| ZNF287 | zinc finger protein 287 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| AGBL5 | ATP/GTP binding protein-like 5 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| APIP | APAF1 interacting protein |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| AURKC | aurora kinase C |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BCL9 | B-cell CLL/lymphoma 9 |
| CCDC28A | coiled-coil domain containing 28A |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) |
| CLSTN2 | calsyntenin 2 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNPY3 | canopy FGF signaling regulator 3 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CPTP | ceramide-1-phosphate transfer protein |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| DCP1A | decapping mRNA 1A |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DHDDS | dehydrodolichyl diphosphate synthase |
| DRP2 | dystrophin related protein 2 |
| DSCAM | Down syndrome cell adhesion molecule |
| EGR3 | early growth response 3 |
| EPHA4 | EPH receptor A4 |
| FKBPL | FK506 binding protein like |
| FOXC1 | forkhead box C1 |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GMIP | GEM interacting protein |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 |
| GNB3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| HELLS | helicase, lymphoid-specific |
| HOOK1 | hook microtubule-tethering protein 1 |
| HPN | hepsin |
| IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| JOSD1 | Josephin domain containing 1 |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLHL28 | kelch-like family member 28 |
| KLHL36 | kelch-like family member 36 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LOXL1 | lysyl oxidase-like 1 |
| MAGEF1 | melanoma antigen family F1 |
| MALL | mal, T-cell differentiation protein-like |
| MSX1 | msh homeobox 1 |
| NARF | nuclear prelamin A recognition factor |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NCK2 | NCK adaptor protein 2 |
| NCS1 | neuronal calcium sensor 1 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NUPL1 | nucleoporin like 1 |
| ORC1 | origin recognition complex, subunit 1 |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
| PDZD7 | PDZ domain containing 7 |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PFKFB1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PISD | phosphatidylserine decarboxylase |
| PPP1R8 | protein phosphatase 1, regulatory subunit 8 |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PQLC3 | PQ loop repeat containing 3 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RHOF | ras homolog family member F (in filopodia) |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SMYD5 | SMYD family member 5 |
| SNX10 | sorting nexin 10 |
| SNX6 | sorting nexin 6 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TGM3 | transglutaminase 3 |
| THBS3 | thrombospondin 3 |
| TMEM51 | transmembrane protein 51 |
| TRAF5 | TNF receptor-associated factor 5 |
| TRAPPC12 | trafficking protein particle complex 12 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| TSPAN32 | tetraspanin 32 |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| TTC4 | tetratricopeptide repeat domain 4 |
| UFSP2 | UFM1-specific peptidase 2 |
| VIM | vimentin |
| WDR13 | WD repeat domain 13 |
| YEATS2 | YEATS domain containing 2 |
| ZNF428 | zinc finger protein 428 |
| ZNF480 | zinc finger protein 480 |
| ZNF580 | zinc finger protein 580 |
| ZNF91 | zinc finger protein 91 |