| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the monastrol-614 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAMP | angio-associated, migratory cell protein |
| ACLY | ATP citrate lyase |
| ACTN1 | actinin, alpha 1 |
| ADIPOR2 | adiponectin receptor 2 |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AFTPH | aftiphilin |
| BPTF | bromodomain PHD finger transcription factor |
| BUB3 | BUB3 mitotic checkpoint protein |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CANT1 | calcium activated nucleotidase 1 |
| CDK1 | cyclin-dependent kinase 1 |
| CENPA | centromere protein A |
| CERS6 | ceramide synthase 6 |
| CKAP5 | cytoskeleton associated protein 5 |
| CLDN7 | claudin 7 |
| CLINT1 | clathrin interactor 1 |
| CLN3 | ceroid-lipofuscinosis, neuronal 3 |
| CNN2 | calponin 2 |
| COPZ1 | coatomer protein complex, subunit zeta 1 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) |
| CPT1A | carnitine palmitoyltransferase 1A (liver) |
| DCTN5 | dynactin 5 (p25) |
| DDX27 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 |
| DHCR24 | 24-dehydrocholesterol reductase |
| DNASE2 | deoxyribonuclease II, lysosomal |
| DYNLRB1 | dynein, light chain, roadblock-type 1 |
| EIF2B4 | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa |
| EIF2S1 | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa |
| EIF3L | eukaryotic translation initiation factor 3, subunit L |
| EWSR1 | EWS RNA-binding protein 1 |
| FAM65A | family with sequence similarity 65, member A |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GATA3 | GATA binding protein 3 |
| GLUD1 | glutamate dehydrogenase 1 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 |
| GOT2 | glutamic-oxaloacetic transaminase 2, mitochondrial |
| GSE1 | Gse1 coiled-coil protein |
| GTF2A2 | general transcription factor IIA, 2, 12kDa |
| HIST1H2BF | histone cluster 1, H2bf |
| HIST3H2A | histone cluster 3, H2a |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R |
| HSPA4 | heat shock 70kDa protein 4 |
| IFITM3 | interferon induced transmembrane protein 3 |
| IFRD2 | interferon-related developmental regulator 2 |
| INSIG1 | insulin induced gene 1 |
| KIAA0894 | KIAA0894 protein |
| LAGE3 | L antigen family, member 3 |
| LITAF | lipopolysaccharide-induced TNF factor |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MANF | mesencephalic astrocyte-derived neurotrophic factor |
| MAP3K11 | mitogen-activated protein kinase kinase kinase 11 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like |
| MBNL1 | muscleblind-like splicing regulator 1 |
| MBTPS1 | membrane-bound transcription factor peptidase, site 1 |
| METTL13 | methyltransferase like 13 |
| MOB4 | MOB family member 4, phocein |
| MTDH | metadherin |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| MYO1C | myosin IC |
| PARP1 | poly (ADP-ribose) polymerase 1 |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase |
| PCNP | PEST proteolytic signal containing nuclear protein |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P |
| PMS2P1 | postmeiotic segregation increased 2 pseudogene 1 |
| PRKCI | protein kinase C, iota |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 |
| PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 |
| PSMG2 | proteasome (prosome, macropain) assembly chaperone 2 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 |
| PTPRF | protein tyrosine phosphatase, receptor type, F |
| RAB31 | RAB31, member RAS oncogene family |
| RAD1 | RAD1 checkpoint DNA exonuclease |
| RND3 | Rho family GTPase 3 |
| RWDD1 | RWD domain containing 1 |
| S100A11 | S100 calcium binding protein A11 |
| SCAMP1 | secretory carrier membrane protein 1 |
| SERP1 | stress-associated endoplasmic reticulum protein 1 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 |
| SNRPA1 | small nuclear ribonucleoprotein polypeptide A' |
| SNX3 | sorting nexin 3 |
| SP3 | Sp3 transcription factor |
| SPTSSA | serine palmitoyltransferase, small subunit A |
| TM9SF3 | transmembrane 9 superfamily member 3 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) |
| TOB1 | transducer of ERBB2, 1 |
| TPD52 | tumor protein D52 |
| TRIB3 | tribbles pseudokinase 3 |
| TROVE2 | TROVE domain family, member 2 |
| TUBD1 | tubulin, delta 1 |
| TXNDC9 | thioredoxin domain containing 9 |
| UBE2V2 | ubiquitin-conjugating enzyme E2 variant 2 |
| WAC | WW domain containing adaptor with coiled-coil |
| WRB | tryptophan rich basic protein |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 |
| ABHD17A | abhydrolase domain containing 17A |
| ADRM1 | adhesion regulating molecule 1 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase |
| ARAF | A-Raf proto-oncogene, serine/threonine kinase |
| ARCN1 | archain 1 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa |
| ATOX1 | antioxidant 1 copper chaperone |
| ATP6AP1 | ATPase, H+ transporting, lysosomal accessory protein 1 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 |
| BCL7C | B-cell CLL/lymphoma 7C |
| BSG | basigin (Ok blood group) |
| C12ORF10 | chromosome 12 open reading frame 10 |
| C14ORF169 | chromosome 14 open reading frame 169 |
| C19ORF53 | chromosome 19 open reading frame 53 |
| C6ORF48 | chromosome 6 open reading frame 48 |
| CBX4 | chromobox homolog 4 |
| CCT7 | chaperonin containing TCP1, subunit 7 (eta) |
| CENPB | centromere protein B, 80kDa |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 |
| CIB1 | calcium and integrin binding 1 (calmyrin) |
| CISD1 | CDGSH iron sulfur domain 1 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa |
| CSK | c-src tyrosine kinase |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa |
| CTPS1 | CTP synthase 1 |
| CTSA | cathepsin A |
| CXORF40A | chromosome X open reading frame 40A |
| CXORF40B | chromosome X open reading frame 40B |
| DCTN3 | dynactin 3 (p22) |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 |
| DEF8 | differentially expressed in FDCP 8 homolog (mouse) |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 |
| DNAAF5 | dynein, axonemal, assembly factor 5 |
| EIF2B3 | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa |
| ERP29 | endoplasmic reticulum protein 29 |
| ESYT1 | extended synaptotagmin-like protein 1 |
| FBP1 | fructose-1,6-bisphosphatase 1 |
| FOXA1 | forkhead box A1 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| G6PD | glucose-6-phosphate dehydrogenase |
| GOLGA5 | golgin A5 |
| GPS1 | G protein pathway suppressor 1 |
| H1FX | H1 histone family, member X |
| HMGN3 | high mobility group nucleosomal binding domain 3 |
| HRSP12 | heat-responsive protein 12 |
| HSPBP1 | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 |
| IRF3 | interferon regulatory factor 3 |
| ISOC2 | isochorismatase domain containing 2 |
| JAK1 | Janus kinase 1 |
| KIF20A | kinesin family member 20A |
| LAMTOR2 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LSR | lipolysis stimulated lipoprotein receptor |
| MAGED1 | melanoma antigen family D1 |
| MEPCE | methylphosphate capping enzyme |
| MISP | mitotic spindle positioning |
| MRPL12 | mitochondrial ribosomal protein L12 |
| MRPL39 | mitochondrial ribosomal protein L39 |
| MTX1 | metaxin 1 |
| MZT2A | mitotic spindle organizing protein 2A |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) |
| NAT10 | N-acetyltransferase 10 (GCN5-related) |
| NDUFB11 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NIT2 | nitrilase family, member 2 |
| NOP10 | NOP10 ribonucleoprotein |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) |
| NRD1 | nardilysin (N-arginine dibasic convertase) |
| PES1 | pescadillo ribosomal biogenesis factor 1 |
| PHF10 | PHD finger protein 10 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PITRM1 | pitrilysin metallopeptidase 1 |
| PMPCB | peptidase (mitochondrial processing) beta |
| PPIH | peptidylprolyl isomerase H (cyclophilin H) |
| PRPF19 | pre-mRNA processing factor 19 |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase |
| RHOB | ras homolog family member B |
| RNMTL1 | RNA methyltransferase like 1 |
| RNPEP | arginyl aminopeptidase (aminopeptidase B) |
| RPL34 | ribosomal protein L34 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RPP40 | ribonuclease P/MRP 40kDa subunit |
| RPS18 | ribosomal protein S18 |
| SDC4 | syndecan 4 |
| SHFM1 | split hand/foot malformation (ectrodactyly) type 1 |
| SNF8 | SNF8, ESCRT-II complex subunit |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| SYTL2 | synaptotagmin-like 2 |
| TK1 | thymidine kinase 1, soluble |
| TMEM109 | transmembrane protein 109 |
| TTC19 | tetratricopeptide repeat domain 19 |
| TXNRD1 | thioredoxin reductase 1 |
| UBE2M | ubiquitin-conjugating enzyme E2M |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| UBE3C | ubiquitin protein ligase E3C |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) |
| YIF1A | Yip1 interacting factor homolog A (S. cerevisiae) |
