| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the monastrol-627 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| API5 | apoptosis inhibitor 5 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ASMTL | acetylserotonin O-methyltransferase-like |
| ATXN2 | ataxin 2 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| C1ORF115 | chromosome 1 open reading frame 115 |
| CANT1 | calcium activated nucleotidase 1 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHD3 | chromodomain helicase DNA binding protein 3 |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| CLDN4 | claudin 4 |
| CLK3 | CDC-like kinase 3 |
| CNPPD1 | cyclin Pas1/PHO80 domain containing 1 |
| CSNK1A1 | casein kinase 1, alpha 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DNAJC13 | DnaJ (Hsp40) homolog, subfamily C, member 13 |
| EHD4 | EH-domain containing 4 |
| EML3 | echinoderm microtubule associated protein like 3 |
| ENOSF1 | enolase superfamily member 1 |
| EPS8L1 | EPS8-like 1 |
| ERI3 | ERI1 exoribonuclease family member 3 |
| FAM134A | family with sequence similarity 134, member A |
| FAM134C | family with sequence similarity 134, member C |
| FBXO9 | F-box protein 9 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 |
| HEATR1 | HEAT repeat containing 1 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H3G | histone cluster 1, H3g |
| HLA-B | major histocompatibility complex, class I, B |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| ITCH | itchy E3 ubiquitin protein ligase |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KRT86 | keratin 86, type II |
| LPPR2 | lipid phosphate phosphatase-related protein type 2 |
| MACF1 | microtubule-actin crosslinking factor 1 |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 |
| MED9 | mediator complex subunit 9 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 |
| MOB4 | MOB family member 4, phocein |
| MORC2 | MORC family CW-type zinc finger 2 |
| MT1HL1 | metallothionein 1H-like 1 |
| MUC1 | mucin 1, cell surface associated |
| MUC3A | mucin 3A, cell surface associated |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PFDN4 | prefoldin subunit 4 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLD3 | phospholipase D family, member 3 |
| PLXNA1 | plexin A1 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PPCS | phosphopantothenoylcysteine synthetase |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B |
| PRKCH | protein kinase C, eta |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| RAB32 | RAB32, member RAS oncogene family |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| RPL18 | ribosomal protein L18 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SDHC | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa |
| SFXN1 | sideroflexin 1 |
| SLC25A20 | solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| STX6 | syntaxin 6 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TBC1D22A | TBC1 domain family, member 22A |
| TBCC | tubulin folding cofactor C |
| TCF3 | transcription factor 3 |
| TESK1 | testis-specific kinase 1 |
| TGFB3 | transforming growth factor, beta 3 |
| THOC1 | THO complex 1 |
| TMEM132A | transmembrane protein 132A |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TOM1L1 | target of myb1 (chicken)-like 1 |
| TRIB3 | tribbles pseudokinase 3 |
| TRMT61A | tRNA methyltransferase 61A |
| TXNDC15 | thioredoxin domain containing 15 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) |
| ZNF212 | zinc finger protein 212 |
| ZNF22 | zinc finger protein 22 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| AKIRIN1 | akirin 1 |
| ASNSD1 | asparagine synthetase domain containing 1 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ASUN | asunder spermatogenesis regulator |
| B3GNT1 | |
| BYSL | bystin-like |
| CA2 | carbonic anhydrase II |
| CASC3 | cancer susceptibility candidate 3 |
| CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
| CCDC71 | coiled-coil domain containing 71 |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CSK | c-src tyrosine kinase |
| DCAF6 | DDB1 and CUL4 associated factor 6 |
| DENND4B | DENN/MADD domain containing 4B |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 |
| DPF2 | D4, zinc and double PHD fingers family 2 |
| EDC4 | enhancer of mRNA decapping 4 |
| EIF2B3 | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM46A | family with sequence similarity 46, member A |
| FAM57A | family with sequence similarity 57, member A |
| FDXR | ferredoxin reductase |
| FNDC3B | fibronectin type III domain containing 3B |
| FOXC1 | forkhead box C1 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GCH1 | GTP cyclohydrolase 1 |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GUSB | glucuronidase, beta |
| HELLS | helicase, lymphoid-specific |
| IMPAD1 | inositol monophosphatase domain containing 1 |
| IRS1 | insulin receptor substrate 1 |
| IRX5 | iroquois homeobox 5 |
| KAT2A | K(lysine) acetyltransferase 2A |
| KCTD2 | potassium channel tetramerization domain containing 2 |
| KEAP1 | kelch-like ECH-associated protein 1 |
| KIF1BP | KIF1 binding protein |
| LMNB1 | lamin B1 |
| LOXL1 | lysyl oxidase-like 1 |
| MAP7D1 | MAP7 domain containing 1 |
| MCM10 | minichromosome maintenance complex component 10 |
| MON1B | MON1 secretory trafficking family member B |
| MREG | melanoregulin |
| MRPL19 | mitochondrial ribosomal protein L19 |
| MRPS10 | mitochondrial ribosomal protein S10 |
| MSL1 | male-specific lethal 1 homolog (Drosophila) |
| MTPAP | mitochondrial poly(A) polymerase |
| MVD | mevalonate (diphospho) decarboxylase |
| MYNN | myoneurin |
| NFE2L2 | nuclear factor, erythroid 2-like 2 |
| NIPA2 | non imprinted in Prader-Willi/Angelman syndrome 2 |
| NSL1 | NSL1, MIS12 kinetochore complex component |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PALM | paralemmin |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| POLB | polymerase (DNA directed), beta |
| PPAN | peter pan homolog (Drosophila) |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRKRIR | protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) |
| PRPSAP2 | phosphoribosyl pyrophosphate synthetase-associated protein 2 |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| PXMP2 | peroxisomal membrane protein 2, 22kDa |
| QDPR | quinoid dihydropteridine reductase |
| RAB4B | RAB4B, member RAS oncogene family |
| RAI14 | retinoic acid induced 14 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RBBP8 | retinoblastoma binding protein 8 |
| RGS16 | regulator of G-protein signaling 16 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RSRC1 | arginine/serine-rich coiled-coil 1 |
| SCFD1 | sec1 family domain containing 1 |
| SIL1 | SIL1 nucleotide exchange factor |
| SLC10A3 | solute carrier family 10, member 3 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLC25A46 | solute carrier family 25, member 46 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| STYXL1 | serine/threonine/tyrosine interacting-like 1 |
| TMEM180 | transmembrane protein 180 |
| TP53BP2 | tumor protein p53 binding protein 2 |
| TPSD1 | tryptase delta 1 |
| TSC1 | tuberous sclerosis 1 |
| TSPAN1 | tetraspanin 1 |
| TSPYL4 | TSPY-like 4 |
| TYK2 | tyrosine kinase 2 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 |
| UBQLN2 | ubiquilin 2 |
| UTP3 | UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) |
| WDR37 | WD repeat domain 37 |
| WDR43 | WD repeat domain 43 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta |
| ZBTB5 | zinc finger and BTB domain containing 5 |
| ZNF263 | zinc finger protein 263 |
| ZNF747 | zinc finger protein 747 |
