| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the monastrol-668 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 |
| ALPK1 | alpha-kinase 1 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BMP7 | bone morphogenetic protein 7 |
| BMP8A | bone morphogenetic protein 8a |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| CCNT1 | cyclin T1 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CRYM | crystallin, mu |
| DCLRE1A | DNA cross-link repair 1A |
| DCN | decorin |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DUS2 | dihydrouridine synthase 2 |
| EDA | ectodysplasin A |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 |
| ERCC4 | excision repair cross-complementation group 4 |
| FA2H | fatty acid 2-hydroxylase |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| GK | glycerol kinase |
| GLRX3 | glutaredoxin 3 |
| GM2A | GM2 ganglioside activator |
| GPSM2 | G-protein signaling modulator 2 |
| H2AFY2 | H2A histone family, member Y2 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HAP1 | huntingtin-associated protein 1 |
| HIST1H1D | histone cluster 1, H1d |
| HOXA4 | homeobox A4 |
| HOXD9 | homeobox D9 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IGFALS | insulin-like growth factor binding protein, acid labile subunit |
| IL13RA1 | interleukin 13 receptor, alpha 1 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| INTS7 | integrator complex subunit 7 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KLHL24 | kelch-like family member 24 |
| KYNU | kynureninase |
| LRRN2 | leucine rich repeat neuronal 2 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MED1 | mediator complex subunit 1 |
| METTL2B | methyltransferase like 2B |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MNS1 | meiosis-specific nuclear structural 1 |
| MXD4 | MAX dimerization protein 4 |
| MYL10 | myosin, light chain 10, regulatory |
| MZF1 | myeloid zinc finger 1 |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 |
| NFATC2IP | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| NPFFR1 | neuropeptide FF receptor 1 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDZD3 | PDZ domain containing 3 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLCE1 | phospholipase C, epsilon 1 |
| PLCL2 | phospholipase C-like 2 |
| PLSCR3 | phospholipid scramblase 3 |
| PON3 | paraoxonase 3 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PRDM11 | PR domain containing 11 |
| PRKAA1 | protein kinase, AMP-activated, alpha 1 catalytic subunit |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| REC8 | REC8 meiotic recombination protein |
| RGS16 | regulator of G-protein signaling 16 |
| RGS3 | regulator of G-protein signaling 3 |
| RNF141 | ring finger protein 141 |
| RPL37A | ribosomal protein L37a |
| RPS2 | ribosomal protein S2 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RUNDC3A | RUN domain containing 3A |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SPN | sialophorin |
| SYT2 | synaptotagmin II |
| SZRD1 | SUZ RNA binding domain containing 1 |
| TBC1D2B | TBC1 domain family, member 2B |
| TCF4 | transcription factor 4 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TSPAN8 | tetraspanin 8 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| TXNRD3 | thioredoxin reductase 3 |
| UBQLN4 | ubiquilin 4 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| WDR18 | WD repeat domain 18 |
| WNK1 | WNK lysine deficient protein kinase 1 |
| ZGPAT | zinc finger, CCCH-type with G patch domain |
| ZNF189 | zinc finger protein 189 |
| ZNF318 | zinc finger protein 318 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| AATF | apoptosis antagonizing transcription factor |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ADCYAP1 | adenylate cyclase activating polypeptide 1 (pituitary) |
| ADORA3 | adenosine A3 receptor |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ART1 | ADP-ribosyltransferase 1 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C9ORF78 | chromosome 9 open reading frame 78 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CAMKV | CaM kinase-like vesicle-associated |
| CASD1 | CAS1 domain containing 1 |
| CCNA1 | cyclin A1 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CHN1 | chimerin 1 |
| CIC | capicua transcriptional repressor |
| CLEC16A | C-type lectin domain family 16, member A |
| CPOX | coproporphyrinogen oxidase |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DYSF | dysferlin |
| EPN3 | epsin 3 |
| ERF | Ets2 repressor factor |
| EXOSC9 | exosome component 9 |
| FAM192A | family with sequence similarity 192, member A |
| FAM63A | family with sequence similarity 63, member A |
| FDXR | ferredoxin reductase |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FMO4 | flavin containing monooxygenase 4 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HAGH | hydroxyacylglutathione hydrolase |
| HAS2 | hyaluronan synthase 2 |
| HDAC5 | histone deacetylase 5 |
| HDAC7 | histone deacetylase 7 |
| HIST1H3G | histone cluster 1, H3g |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOXC11 | homeobox C11 |
| KIFC3 | kinesin family member C3 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KLHL25 | kelch-like family member 25 |
| KLK8 | kallikrein-related peptidase 8 |
| LINC00216 | long intergenic non-protein coding RNA 216 |
| LRRC15 | leucine rich repeat containing 15 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MED23 | mediator complex subunit 23 |
| METTL22 | methyltransferase like 22 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NELL2 | NEL-like 2 (chicken) |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NUAK1 | NUAK family, SNF1-like kinase, 1 |
| NVL | nuclear VCP-like |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PAK1IP1 | PAK1 interacting protein 1 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PC | pyruvate carboxylase |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PMEL | premelanosome protein |
| PMM2 | phosphomannomutase 2 |
| POU5F1B | POU class 5 homeobox 1B |
| PRR16 | proline rich 16 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 |
| PYROXD1 | pyridine nucleotide-disulphide oxidoreductase domain 1 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RASL11B | RAS-like, family 11, member B |
| RNF39 | ring finger protein 39 |
| SASH3 | SAM and SH3 domain containing 3 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SLC6A13 | solute carrier family 6 (neurotransmitter transporter), member 13 |
| SNAI2 | snail family zinc finger 2 |
| SPON2 | spondin 2, extracellular matrix protein |
| SS18L1 | synovial sarcoma translocation gene on chromosome 18-like 1 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 |
| TFB2M | transcription factor B2, mitochondrial |
| TGS1 | trimethylguanosine synthase 1 |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TMPRSS11D | transmembrane protease, serine 11D |
| TRIP10 | thyroid hormone receptor interactor 10 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| TSPAN32 | tetraspanin 32 |
| VRK2 | vaccinia related kinase 2 |
| XPA | xeroderma pigmentosum, complementation group A |
| ZNF408 | zinc finger protein 408 |
| ZNF432 | zinc finger protein 432 |
| ZNF557 | zinc finger protein 557 |
| ZNF696 | zinc finger protein 696 |
| ZNF8 | zinc finger protein 8 |
