| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the monastrol-681 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOT9 | acyl-CoA thioesterase 9 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANAPC10 | anaphase promoting complex subunit 10 |
| APH1B | APH1B gamma secretase subunit |
| ARFRP1 | ADP-ribosylation factor related protein 1 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BECN1 | beclin 1, autophagy related |
| C12ORF49 | chromosome 12 open reading frame 49 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CDK17 | cyclin-dependent kinase 17 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLIC4 | chloride intracellular channel 4 |
| CRNKL1 | crooked neck pre-mRNA splicing factor 1 |
| CRYAB | crystallin, alpha B |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CTTN | cortactin |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| CYP4A11 | cytochrome P450, family 4, subfamily A, polypeptide 11 |
| DCP1A | decapping mRNA 1A |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX52 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DUSP13 | dual specificity phosphatase 13 |
| DXO | decapping exoribonuclease |
| EPS8L1 | EPS8-like 1 |
| ERCC6L | excision repair cross-complementation group 6-like |
| FAM153A | family with sequence similarity 153, member A |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FOSL1 | FOS-like antigen 1 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GRK5 | G protein-coupled receptor kinase 5 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HLA-G | major histocompatibility complex, class I, G |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IFRD1 | interferon-related developmental regulator 1 |
| INO80B | INO80 complex subunit B |
| INSIG1 | insulin induced gene 1 |
| IRF6 | interferon regulatory factor 6 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LIG3 | ligase III, DNA, ATP-dependent |
| MOB3B | MOB kinase activator 3B |
| MYL10 | myosin, light chain 10, regulatory |
| MYO1A | myosin IA |
| NADK | NAD kinase |
| NCAPH | non-SMC condensin I complex, subunit H |
| NFATC2IP | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein |
| NKIRAS2 | NFKB inhibitor interacting Ras-like 2 |
| NOC4L | nucleolar complex associated 4 homolog (S. cerevisiae) |
| NXPH3 | neurexophilin 3 |
| OSGEP | O-sialoglycoprotein endopeptidase |
| PCDH12 | protocadherin 12 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PDE6D | phosphodiesterase 6D, cGMP-specific, rod, delta |
| PLCG1 | phospholipase C, gamma 1 |
| PON2 | paraoxonase 2 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PTK2B | protein tyrosine kinase 2 beta |
| RAP1GDS1 | RAP1, GTP-GDP dissociation stimulator 1 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RNF24 | ring finger protein 24 |
| RPS2 | ribosomal protein S2 |
| S100P | S100 calcium binding protein P |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SETD2 | SET domain containing 2 |
| SH3PXD2A | SH3 and PX domains 2A |
| SIL1 | SIL1 nucleotide exchange factor |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLC22A18 | solute carrier family 22, member 18 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC35F2 | solute carrier family 35, member F2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SRR | serine racemase |
| STX7 | syntaxin 7 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TBXA2R | thromboxane A2 receptor |
| TPCN1 | two pore segment channel 1 |
| TRAC | T cell receptor alpha constant |
| TRIM3 | tripartite motif containing 3 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) |
| UST | uronyl-2-sulfotransferase |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) |
| VRK3 | vaccinia related kinase 3 |
| VWA5A | von Willebrand factor A domain containing 5A |
| ZBTB40 | zinc finger and BTB domain containing 40 |
| ZNF236 | zinc finger protein 236 |
| ZNF771 | zinc finger protein 771 |
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACKR3 | atypical chemokine receptor 3 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| ARRB2 | arrestin, beta 2 |
| ATG7 | autophagy related 7 |
| AVPR1B | arginine vasopressin receptor 1B |
| BCCIP | BRCA2 and CDKN1A interacting protein |
| BTBD2 | BTB (POZ) domain containing 2 |
| C16ORF62 | chromosome 16 open reading frame 62 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CA2 | carbonic anhydrase II |
| CASC3 | cancer susceptibility candidate 3 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) |
| CLPP | caseinolytic mitochondrial matrix peptidase proteolytic subunit |
| CMTR1 | cap methyltransferase 1 |
| CPTP | ceramide-1-phosphate transfer protein |
| CRTAC1 | cartilage acidic protein 1 |
| DENND1B | DENN/MADD domain containing 1B |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| ECHDC1 | ethylmalonyl-CoA decarboxylase 1 |
| EDAR | ectodysplasin A receptor |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| EPM2AIP1 | EPM2A (laforin) interacting protein 1 |
| ETV7 | ets variant 7 |
| EVL | Enah/Vasp-like |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FAM193A | family with sequence similarity 193, member A |
| FAM46A | family with sequence similarity 46, member A |
| FOLR2 | folate receptor 2 (fetal) |
| FOXD1 | forkhead box D1 |
| GNB3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPATCH3 | G patch domain containing 3 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HECTD3 | HECT domain containing E3 ubiquitin protein ligase 3 |
| HOOK2 | hook microtubule-tethering protein 2 |
| IL17RA | interleukin 17 receptor A |
| IRS1 | insulin receptor substrate 1 |
| ITGA10 | integrin, alpha 10 |
| KIF3B | kinesin family member 3B |
| KLHL25 | kelch-like family member 25 |
| LTBP3 | latent transforming growth factor beta binding protein 3 |
| LYRM2 | LYR motif containing 2 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) |
| MON1B | MON1 secretory trafficking family member B |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NOTCH1 | notch 1 |
| NUP62 | nucleoporin 62kDa |
| PAK1IP1 | PAK1 interacting protein 1 |
| PELP1 | proline, glutamate and leucine rich protein 1 |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PLD2 | phospholipase D2 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PODXL | podocalyxin-like |
| PRAF2 | PRA1 domain family, member 2 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RBBP5 | retinoblastoma binding protein 5 |
| RBM47 | RNA binding motif protein 47 |
| RNF141 | ring finger protein 141 |
| RNF220 | ring finger protein 220 |
| RNF38 | ring finger protein 38 |
| RNH1 | ribonuclease/angiogenin inhibitor 1 |
| RPAP1 | RNA polymerase II associated protein 1 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SLC10A3 | solute carrier family 10, member 3 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLN | sarcolipin |
| SMAD7 | SMAD family member 7 |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| STK16 | serine/threonine kinase 16 |
| SYT2 | synaptotagmin II |
| TNRC6B | trinucleotide repeat containing 6B |
| TSC22D4 | TSC22 domain family, member 4 |
| TUBA3C | tubulin, alpha 3c |
| UBQLN4 | ubiquilin 4 |
| UGDH | UDP-glucose 6-dehydrogenase |
| VIM | vimentin |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR46 | WD repeat domain 46 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF185 | zinc finger protein 185 (LIM domain) |
| ZNF408 | zinc finger protein 408 |
| ZNF574 | zinc finger protein 574 |
| ZNF587 | zinc finger protein 587 |
| ZNF611 | zinc finger protein 611 |
| ZNF652 | zinc finger protein 652 |
| ZNF669 | zinc finger protein 669 |
| ZNF710 | zinc finger protein 710 |
| ZNF74 | zinc finger protein 74 |
