monensin-1105 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

199 genes differentially expressed following the monensin-1105 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADVL acyl-CoA dehydrogenase, very long chain
ACAT2 acetyl-CoA acetyltransferase 2
ALDOC aldolase C, fructose-bisphosphate
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
AREG amphiregulin
ARMCX1 armadillo repeat containing, X-linked 1
BCL6 B-cell CLL/lymphoma 6
BHLHE40 basic helix-loop-helix family, member e40
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BTG1 B-cell translocation gene 1, anti-proliferative
C14ORF1 chromosome 14 open reading frame 1
C1ORF106 chromosome 1 open reading frame 106
CCNG2 cyclin G2
CDYL chromodomain protein, Y-like
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CYTH1 cytohesin 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DHCR7 7-dehydrocholesterol reductase
DNMBP dynamin binding protein
DPYSL2 dihydropyrimidinase-like 2
DUSP4 dual specificity phosphatase 4
DVL2 dishevelled segment polarity protein 2
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EGLN1 egl-9 family hypoxia-inducible factor 1
EGR3 early growth response 3
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ENO2 enolase 2 (gamma, neuronal)
EPM2AIP1 EPM2A (laforin) interacting protein 1
FAM114A1 family with sequence similarity 114, member A1
FAM174B family with sequence similarity 174, member B
FDFT1 farnesyl-diphosphate farnesyltransferase 1
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GMDS GDP-mannose 4,6-dehydratase
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GOLGA2 golgin A2
GRAMD3 GRAM domain containing 3
GTF2IRD1 GTF2I repeat domain containing 1
HBP1 HMG-box transcription factor 1
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HFE hemochromatosis
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HS1BP3 HCLS1 binding protein 3
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
IDI1 isopentenyl-diphosphate delta isomerase 1
ING1 inhibitor of growth family, member 1
INSIG1 insulin induced gene 1
INSIG2 insulin induced gene 2
ITCH itchy E3 ubiquitin protein ligase
KAT5 K(lysine) acetyltransferase 5
KDM3A lysine (K)-specific demethylase 3A
KLF6 Kruppel-like factor 6
KLHL24 kelch-like family member 24
LDLR low density lipoprotein receptor
LGALS8 lectin, galactoside-binding, soluble, 8
LPIN1 lipin 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGED1 melanoma antigen family D1
MARCKS myristoylated alanine-rich protein kinase C substrate
MSMO1 methylsterol monooxygenase 1
MTA1 metastasis associated 1
MVD mevalonate (diphospho) decarboxylase
MVK mevalonate kinase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEU1 sialidase 1 (lysosomal sialidase)
NOAZFP nucleolar atypical zinc finger
NPC1 Niemann-Pick disease, type C1
OSBPL2 oxysterol binding protein-like 2
PCNXL4 pecanex-like 4 (Drosophila)
PCOLCE2 procollagen C-endopeptidase enhancer 2
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PGM3 phosphoglucomutase 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PRSS8 protease, serine, 8
RRAGD Ras-related GTP binding D
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC38A2 solute carrier family 38, member 2
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SMC5 structural maintenance of chromosomes 5
SPRED2 sprouty-related, EVH1 domain containing 2
SQLE squalene epoxidase
TESK2 testis-specific kinase 2
TRIB3 tribbles pseudokinase 3
TRIM2 tripartite motif containing 2
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
VEGFA vascular endothelial growth factor A
WBP2 WW domain binding protein 2
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZNF292 zinc finger protein 292
ZNF580 zinc finger protein 580

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACOT8 acyl-CoA thioesterase 8
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ASTE1 asteroid homolog 1 (Drosophila)
C11ORF95 chromosome 11 open reading frame 95
C12ORF43 chromosome 12 open reading frame 43
C1ORF115 chromosome 1 open reading frame 115
C1ORF56 chromosome 1 open reading frame 56
C9ORF3 chromosome 9 open reading frame 3
CCDC6 coiled-coil domain containing 6
CD3EAP CD3e molecule, epsilon associated protein
CDKN2AIP CDKN2A interacting protein
CEP72 centrosomal protein 72kDa
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CLDN7 claudin 7
CPTP ceramide-1-phosphate transfer protein
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DCLRE1A DNA cross-link repair 1A
DEPDC1 DEP domain containing 1
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ERF Ets2 repressor factor
EYA2 EYA transcriptional coactivator and phosphatase 2
FAM86B1 family with sequence similarity 86, member B1
FAM86C1 family with sequence similarity 86, member C1
FBXW4 F-box and WD repeat domain containing 4
FCHSD2 FCH and double SH3 domains 2
GLB1L2 galactosidase, beta 1-like 2
GLMN glomulin, FKBP associated protein
GPATCH2 G patch domain containing 2
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H3G histone cluster 1, H3g
HOXC11 homeobox C11
HPS6 Hermansky-Pudlak syndrome 6
HSPA1A heat shock 70kDa protein 1A
IP6K2 inositol hexakisphosphate kinase 2
JADE1 jade family PHD finger 1
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LYPD3 LY6/PLAUR domain containing 3
MAMLD1 mastermind-like domain containing 1
MANSC1 MANSC domain containing 1
MAP6D1 MAP6 domain containing 1
MAVS mitochondrial antiviral signaling protein
MCM9 minichromosome maintenance complex component 9
NAP1L2 nucleosome assembly protein 1-like 2
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NME6 NME/NM23 nucleoside diphosphate kinase 6
NMU neuromedin U
NOL9 nucleolar protein 9
OPHN1 oligophrenin 1
PAK1IP1 PAK1 interacting protein 1
PCF11 PCF11 cleavage and polyadenylation factor subunit
PCTP phosphatidylcholine transfer protein
PGS1 phosphatidylglycerophosphate synthase 1
PRMT7 protein arginine methyltransferase 7
PTCD2 pentatricopeptide repeat domain 2
RBM14 RNA binding motif protein 14
RBM38 RNA binding motif protein 38
RLN2 relaxin 2
RPA2 replication protein A2, 32kDa
RPS17P5 ribosomal protein S17 pseudogene 5
RPUSD2 RNA pseudouridylate synthase domain containing 2
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SH3BGR SH3 domain binding glutamate-rich protein
SLC16A6 solute carrier family 16, member 6
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SOBP sine oculis binding protein homolog (Drosophila)
SPATA2L spermatogenesis associated 2-like
TBC1D31 TBC1 domain family, member 31
TFB1M transcription factor B1, mitochondrial
THOP1 thimet oligopeptidase 1
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM159 transmembrane protein 159
TMEM168 transmembrane protein 168
TRAPPC12 trafficking protein particle complex 12
TRAPPC2 trafficking protein particle complex 2
TRIM45 tripartite motif containing 45
TRIM52 tripartite motif containing 52
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TTC4 tetratricopeptide repeat domain 4
TXNIP thioredoxin interacting protein
UNKL unkempt family zinc finger-like
ZBTB38 zinc finger and BTB domain containing 38
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF140 zinc finger protein 140
ZNF239 zinc finger protein 239
ZNF253 zinc finger protein 253
ZNF302 zinc finger protein 302
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF611 zinc finger protein 611
ZNF629 zinc finger protein 629
ZNF721 zinc finger protein 721
ZXDC ZXD family zinc finger C